Advanced Antimicrobial Population PK/PD Modelling workshop

 

You are invited to an exciting workshop held in Liverpool, United Kingdom from the 14th to 16th April 2020 focused on population pharmacokinetics/pharmacodynamics modelling of antimicrobials.

This workshop is suitable for health care practitioners involved in complex drug dosing including clinical pharmacists, infectious diseases physicians, intensive care physicians, transplant physicians and clinical pharmacologists with a background in pharmacokinetic analysis. Also suitable for basic researchers including pharmacologists and translational scientists. 

The 2.5 day workshop will be held In collaboration with the University of Liverpool, Laboratory of Applied Pharmacokinetics and Bioinformatics, Los Angeles and the Centre Hospitalier Universitaire de Nîmes, France

As part of this workshop we will look at complex models including those that investigate the impact of protein binding and renal replacement therapy (dialysis) and models that explore PK changes across a lifetime, as well as optimal design methodology. Pharmacodynamic modelling will explore the effect of antimicrobial exposure on bacterial killing and emergence of resistance, immune system function and effect of combination antimicrobial therapy.

Please join us and our guest speakers and tutors from centres in the United States, Spain, France, the United Kingdom and our own Prof Jason Roberts.

Advanced Antimicrobial Population PK/PD Modelling workshop

Tue 14 Apr 2020 8:00am

Venue

Hope Street Hotel
40 Hope St, Liverpool L1 9DA, United Kingdom

 

ANTIMICROBIAL POPULATION PK/PD MODELLING AND SIMULATION

Using the Pmetrics package for R and the BestDose web-based tool

Venue: Liverpool, UK

April 14-16, 2020

 

Faculty & Tutors

 

  • Prof Michael Neely, University of Southern California, USA
  • Prof George Drusano, University of Florida, USA
  • Prof William Hope, University of Liverpool, UK
  • Dr Clement Boidin, Claude Bernard University, France
  • Dr Claire Roger, CHU Nimes, France
  • Dr Fernando Docobo-Perez, University of Sevilla, Spain
  • Dr Catherine Byrne, Trinity College, Ireland
  • Dr Suzanne Parker, The University of Queensland, Australia
  • Prof Jason Roberts, The University of Queensland, Australia

 

Course Objectives

Using the Pmetrics package for R, users will be able to:

  • Define complex pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/PD) structural models.
  • Analyse complex PK and PK/PD datasets (including presence of immune system, biomarker response and/or emergence of bacterial resistance).
  • Perform basic Monte Carlo simulations for PK and PK/PD analysis.

With the BestDose web-based software tool, users will explore:

  • Perform optimal design analyses for development of PK sampling schedules
  • Application of pharmacometric methods to dose individualization
  • Optimise dosing for an individual patient.

 

A working version of Pmetrics on all attendees laptops is required. This workshop is suitable for health care practitioners involved in complex drug dosing including clinical pharmacists, infectious diseases physicians, intensive care physicians, transplant physicians and clinical pharmacologists. Also suitable for basic researchers including pharmacologists and translational scientists.

 

Workshop Program

Antimicrobial Population PK/PD Modelling and Simulation
DAY 1 Tuesday April 14 - Pharmacokinetic modelling
1200-1300 Lunch and Registration 
1300-1330 What's new in Pmetrics and pharmacometrics? Prof Michael Neely
1330-1400 Review of pre-workshop tutorial Dr Suzanne Parker
1400-1500 Modelling drug protein binding Dr Catherine Byrne
1500-1530 Afternoon Tea
1530-1630 Modelling complex renal replacement therapy data Dr Clement Boidin
1630-1730 Modelling extravascular non-oral drug administration Dr Clement Boidin
1830-2130 Networking dinner
Antimicrobial Population PK/PD Modelling and Simulation
DAY 2 Wednesday April 15 - Pharmacokinetic/Pharmacodynamic modelling
0900-1030 Building models for your data Tutors
1030-1100 Morning tea
1100-1130 Pharmacodynamics (PD) principles Dr Fernando Docobo-Perez
1130-1230 Modelling antibiotic PK/PD - monotherapy Dr Fernando Docobo-Perez
1230-1330 Lunch
1330-1430 Modelling antibiotic PK/PD - combination therapy Prof Michael Neely
1430-1530 Modelling effect of immune system on bacterial killing Prof George Drusano
1530-1600 Afternoon tea
1600-1730 Building models for your data Tutors
Antimicrobial Population PK/PD Modelling and Simulation
DAY 3 - Thursday April 16 - Optimal Design of PK Studies
0900-1030 Modelling PK with biomarker data Prof William Hope
1030-1100 Morning tea
1100-1230 Building models for your data Tutors
1230-1330 Lunch
1330-1430 Optimal design of PK studies Prof Michael Neely
1430-1530 Dose optimisation using BestDose Prof Michael Neely
1530-1600 Afternoon Tea
1600-1730 Dose optimisation using BestDose or Building models for your data Prof Michael Neely
1730 Closing Prof Jason Roberts

 

AU $880.00

Contacts

Nermin Karamujic