Preliminary Program

DAY 1 – Pharmacokinetic modelling
08:00-08:25
Registrations
08:25- 08:35
Welcome
08:35-09:00
Introduction to Pharmacometrics
09:00-10:00
Review of pre-workshop tutorial
10:00-10:30
Morning Tea
10:30-12:30
Fitting data to models in Pmetrics
12:30-13:30
Lunch
13:30-15:00
Details and plotting of Pmetrics objects
15:00-15:30
Afternoon Tea
15:30-17:30
Pmetrics modelling exercises*
18:30- 21:30
Networking Dinner
 
DAY 2 – Pharmacokinetic simulations / Pharmacodynamic modelling
9:00 – 10:30
Simulating and probability of target attainment with Pmetrics
10:30-11:00
Morning Tea
11:00-12:30
Simulation exercises*
12:30-13:30
Lunch
13:30-14:30
Pharmacodynamic principles
14:30-15:30
Building pharmacodynamic models
15:30-16:00
Afternoon Tea
16:00-17:30
Pharmacodynamic modelling exercises*

About Pmetrics pharmacometric modelling workshop

This Pmetrics pharmacometrics modelling workshop is suitable for health care practitioners involved in complex drug dosing including clinical pharmacists, infectious diseases physicians and researchers, intensive care physicians, transplant physicians and clinical pharmacologists. It is also suitable for basic researchers including pharmacologists and translational scientists wanting to learn robust methods for the analysis of data from pharmacokinetic studies.

Learning objectives

1. Using the Pmetrics package for R:

  • Define pharmacokinetic (PK) and pharmacokinetic/pharmacodynamics(PK/PD) structural models that can be solved analytically and models that require differential equations
  • Analyse PK and PK/PD datasets
  • Perform basic Monte Carlo simulations for PK and PK/PD analysis

2. With the antimicrobial dosing software tool, users will explore:

  • Application of pharmacometric methods to dose individualisation
  • Optimise dosing for an individual patient