Researcher biography
National Health and Medical Research Council Career Development Fellow at the University of Queensland and Pharmacist Consultant at the Royal Brisbane and Women's Hospital. Professor Roberts has led multiple international pharmacokinetic studies and holds roles on multiple guideline committees.
Book Chapters
Ulldemolins, Marta and Roberts, Jason A. (2012). How do I adjust antimicrobial daily dosage in patients with MODS? a pharmacist’s contribution. In Jordi Rello, Jeffrey Lipman and Thiago Lisboa (Ed.), Sepsis management: PIRO and MODS (pp. 199-216) Berlin, Germany: Springer.
Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. In Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas (Ed.), Critical Care Update 2009 (pp. 128-142) Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.
Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. In J.-L. Vincent (Ed.), Yearbook of Intensive Care and Emergency Medicine 2010 (pp. 495-506) Brussels, Belgium: Springer Verlag. doi:10.1007/978-3-642-10286-8
Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. In Jean-Daniel Chiche and Leanne M. Aitken (Ed.), Patient safety and quality of care in intensive care medicine (pp. 291-304) Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.
Udy, Andrew, Roberts, Jason A., Boots, Robert J. and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock. In Jordi Rello and Marcos I. Restrepo (Ed.), Sepsis: New strategies for management (pp. 97-102) London: Springer-Verlag. doi:10.1007/978-3-540-79001-3
Roberts, J. A. and Lipman, J. (2007). Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock. In Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez (Ed.), Infectious diseases in critical care 2nd ed. (pp. 122-146) Berlin, Germany; New York, U.S.A.: Springer.
Journal Articles
Sulaiman, Helmi, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2017) Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia. Seminars in Respiratory and Critical Care Medicine, 38 3: 271-286. doi:10.1055/s-0037-1602716
Byrne, Catherine J., Roberts, Jason A., McWhinney, Brett, Fennell, Jerome P., O'Byrne, Philomena, Deasy, Evelyn, Egan, Sean, Desmond, Ronan, Enright, Helen, Ryder, Sheila A., D'Arcy, Deirdre M. and McHugh, Johnny (2017) Variability in trough total and unbound teicoplanin concentrations and achievement of therapeutic drug monitoring targets in adult patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 61 6: . doi:10.1128/AAC.02466-16
Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017) Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 6: 876-882. doi:10.1093/bja/aex026
Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017) Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 5: 589-594. doi:10.1016/j.ijantimicag.2017.01.009
Sole-Lleonart, Candela, Rouby, Jean-Jacques, Blot, Stijn, Poulakou, Garyfallia, Chastre, Jean, Palmer, Lucy B., Bassetti, Matteo, Luyt, Charles-Edouard, Pereira, Jose M. , Riera, Jordi, Felton, Tim, Dhanani, Jayesh, Welte, Tobias, Garcia-Alamino, Jose M., Roberts, Jason A. and Rello, Jordi (2017) Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis. Anesthesiology, 126 5: 890-908. doi:10.1097/ALN.0000000000001570
Konig, Christina, Braune, Stephan, Roberts, Jason A., Nierhaus, Axel, Steinmetz, Oliver M., Baehr, Michael, Frey, Otto R., Langebrake, Claudia and Kluge, Stefan (2017) Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis. Journal of Antimicrobial Chemotherapy, 72 5: 1433-1440. doi:10.1093/jac/dkw592
Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017) Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 5: . doi:10.1128/AAC.02642-16
Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017) What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 1-3. doi:10.1007/s00134-017-4789-x
Coulter, Sonali , Roberts, Jason A., Hajkowicz, Krispin and Halton, Kate (2017) The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence. Infectious Disease Reports, 9 1: 8-12. doi:10.4081/idr.2017.6849
Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017) Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 5: 624-630. doi:10.1016/j.ijantimicag.2016.12.022
Byrne, C. J., Roberts, J. A., McWhinney, B., Ryder, S. A., Fennell, J. P., O'Byrne, P., Deasy, E., Egan, S., Desmond, R., Enright, H., D'Arcy, D. M. and McHugh, J. (2017) Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy. Clinical Microbiology and Infection, . doi:10.1016/j.cmi.2017.02.032
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017) Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 3: . doi:10.1128/AAC.01276-16
Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017) Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 4: 395-402. doi:10.1016/j.ijantimicag.2016.12.014
Silbert, Benjamin I., Ho, Kwok M. , Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017) Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 5: 221-226. doi:10.1089/ars.2016.6845
Roberts, Jason A. , Kumar, Anand and Lipman, Jeffrey (2017) Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 2: 331-336. doi:10.1097/CCM.0000000000002210
Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017) Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 1: 137-144. doi:10.1089/neu.2015.4328
Sime, Fekade Bruck, Johnson, Adam, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A. Bruce, Walters, Kathie Ann, Lipman, Jeffrey , Hope, William W. and Roberts, Jason A. (2017) Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy. Antimicrobial Agents and Chemotherapy, 61 1: . doi:10.1128/AAC.01763-16
Roger, C., Wallis, S.C., Muller, L., Saissi, G., Lipman, J., Bruggemann, R.J., Lefrant, J.-Y. and Roberts, J.A. (2016) Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration. Clinical Pharmacokinetics, 1-12. doi:10.1007/s40262-016-0495-z
Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016) Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 2: 231-239. doi:10.1097/QCO.0000000000000348
Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016) Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 6: 748-752. doi:10.1016/j.ijantimicag.2016.09.021
Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016) Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis. Antimicrobial Agents and Chemotherapy, 60 12: 7402-7406. doi:10.1128/AAC.01657-16
Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016) Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 21: 2235-2242. doi:10.4155/bio-2016-0159
Farkas, Andras, Daroczi, Gergely, Villasurda, Phillip, Dolton, Michael, Nakagaki, Midori and Roberts, Jason A. (2016) Comparative evaluation of the predictive performances of three different structural population pharmacokinetic models to predict future voriconazole concentrations. Antimicrobial Agents and Chemotherapy, 60 11: 6806-6812. doi:10.1128/AAC.00970-16
Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016) Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 5: 542-546. doi:10.1016/j.ijantimicag.2016.08.015
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016) Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 11: 6550-6557. doi:10.1128/AAC.01088-16
Dhanani, Jayesh, Fraser, John F., Chan, Hak-Kim, Rello, Jordi, Cohen, Jeremy and Roberts, Jason A. (2016) Fundamentals of aerosol therapy in critical care. Critical Care, 20 1: . doi:10.1186/s13054-016-1448-5
Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2016) Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study. Critical Care Medicine, 44 10: e923-e929. doi:10.1097/CCM.0000000000001823
Tabah, Alexis, Lipman, Jeffrey and Roberts, Jason A. (2016) Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?. Anaesthesia, Critical Care and Pain Medicine, 35 5: 311-312. doi:10.1016/j.accpm.2016.08.002
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016) Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35 231-239. doi:10.1016/j.jcrc.2016.06.022
Garcia-De-Lorenzo, A., Luque, S., Grau, S., Agrifoglio, A., Cachafeiro, L., Herrero, E., Asensio, M. J., Sanchez, S. M. and Roberts, J. A. (2016) Comparative population plasma and tissue pharmacokinetics of micafungin in critically ill patients with severe burn injuries and patients with complicated intra-abdominal infection. Antimicrobial Agents and Chemotherapy, 60 10: 5914-5921. doi:10.1128/AAC.00727-16
Zelenitsky, S. A., Lawson, C., Calic, D., Ariano, R. E., Roberts, J. A., Lipman, J. and Zhanel, G. G. (2016) Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery. Journal of Antimicrobial Chemotherapy, 71 10: 2902-2908. doi:10.1093/jac/dkw247
Osthoff, Michael, Siegemund, Martin, Balestra, Gianmarco, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2016) Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal. Swiss Medical Weekly, 146 . doi:10.4414/smw.2016.14368
Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016) Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 6: 681-691. doi:10.1164/rccm.201601-0024OC
Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016) Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 9: 957-965.
Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016) Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 9: 1961-1975. doi:10.1016/j.clinthera.2016.07.093
Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2016) Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling. Journal of Antimicrobial Chemotherapy, 71 9: 2509-2520. doi:10.1093/jac/dkw153
Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A., Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratala, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Jr., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L. and Brozek, Jan L. (2016) Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clinical Infectious Diseases, 63 5: E61-E111. doi:10.1093/cid/ciw353
Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A, Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratala, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L. and Brozek, Jan L. (2016) Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clinical Infectious Diseases, 63 5: 575-582. doi:10.1093/cid/ciw504
Hanrahan, Timothy P., Lipman, Jeffrey and Roberts, Jason A. (2016) Antibiotic dosing in obesity: a BIG challenge. Critical Care, 20 240: . doi:10.1186/s13054-016-1426-y
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016) Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 8: 4577-4584. doi:10.1128/AAC.00531-16
Sole-Lleonart, Candela, Rouby, Jean-Jacques, Chastre, Jean, Poulakou, Garyfallia, Palmer, Lucy B., Blot, Stijn, Felton, Tim, Bassetti, Matteo, Luyt, Charles-Eduard, Pereira, Joao Manuel, Riera, Jordi, Welte, Tobias, Roberts, Jason A. and Rello, Jordi (2016) Intratracheal administration of antimicrobial agents in mechanically ventilated adults: an international survey on delivery practices and safety. Respiratory Care, 61 8: 1008-1014. doi:10.4187/respcare.04519
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016) Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. Journal of Critical Care, 34 95-102. doi:10.1016/j.jcrc.2016.04.005
Cristallini, Stefano, Hites, Maya, Kabtouri, Hakim, Roberts, Jason A., Beumier, Marjorie, Cotton, Frederic, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis, Creteur, Jacques and Taccone, Fabio Silvio (2016) New regimen for continuous infusion of vancomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 8: 4750-4756. doi:10.1128/AAC.00330-16
Roger, Claire, Wallis, Steven C., Muller, Laurent, Saissi, Gilbert, Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2016) Influence of renal replacement modalities on amikacin population pharmacokinetics in critically ill patients on continuous renal replacement therapy. Antimicrobial Agents and Chemotherapy, 60 8: 4901-4909. doi:10.1128/AAC.00828-16
Sartelli, Massimo, Weber, Dieter G., Ruppe, Etienne, Bassetti, Matteo, Wright, Brian J., Ansaloni, Luca, Catena, Fausto, Coccolini, Federico, Abu-Zidan, Fikri M., Coimbra, Raul, Moore, Ernest E., Moore, Frederick A., Maier, Ronald V., De Waele, Jan J., Kirkpatrick, Andrew W., Griffiths, Ewen A., Eckmann, Christian, Brink, Adrian J., Mazuski, John E., May, Addison K., Sawyer, Rob G., Mertz, Dominik, Montravers, Philippe, Kumar, Anand, Roberts, Jason A., Vincent, Jean-Louis, Watkins, Richard R., Lowman, Warren, Spellberg, Brad, Abbott, Iain J., Adesunkanmi, Abdulrashid Kayode, Al-Dahir, Sara, Al-Hasan, Majdi N., Agresta, Ferdinando, Althani, Asma A., Ansari, Shamshul, Ansumana, Rashid, Augustin, Goran, Bala, Miklosh, Balogh, Zsolt J., Baraket, Oussama, Bhangu, Aneel, Beltran, Marcelo A., Bernhard, Michael, Biffl, Walter L., Boermeester, Marja A., Brecher, Stephen M., Cherry-Bukowiec, Jill R., Buyne, Otmar R., Cainzos, Miguel A., Cairns, Kelly A., Camacho-Ortiz, Adrian, Chandy, Sujith J., Jusoh, Asri Che, Chichom-Mefire, Alain, Colijn, Caroline, Corcione, Francesco, Cui, Yunfeng, Curcio, Daniel, Delibegovic, Samir, Demetrashvili, Zaza, De Simone, Belinda, Dhingra, Sameer, Diaz, Jose J., Di Carlo, Isidoro, Dillip, Angel, Di Saverio, Salomone, Doyle, Michael P., Dorj, Gereltuya, Dogjani, Agron, Dupont, Herve, Eachempati, Soumitra R., Enani, Mushira Abdulaziz, Egiev, Valery N., Elmangory, Mutasim M., Ferrada, Paula, Fitchett, Joseph R., Fraga, Gustavo P., Guessennd, Nathalie, Giamarellou, Helen, Ghnnam, Wagih, Gkiokas, George, Goldberg, Staphanie R., Gomes, Carlos Augusto, Gomi, Harumi, Guzman-Blanco, Manuel, Haque, Mainul, Hansen, Sonja, Hecker, Andreas, Heizmann, Wolfgang R., Herzog, Torsten, Hodonou, Adrien Montcho, Hong, Suk-Kyung, Kafka-Ritsch, Reinhold, Kaplan, Lewis J., Kapoor, Garima, Karamarkovic, Aleksandar, Kees, Martin G., Kenig, Jakub, Kiguba, Ronald, Kim, Peter K., Kluger, Yoram, Khokha, Vladimir, Koike, Kaoru, Kok, Kenneth Y. Y., Kong, Victory, Knox, Matthew C., Inaba, Kenji, Isik, Arda, Iskandar, Katia, Ivatury, Rao R., Labbate, Maurizio, Labricciosa, Francesco M., Laterre, Pierre-Francois, Latifi, Rifat, Lee, Jae Gil, Lee, Young Ran, Leone, Marc, Leppaniemi, Ari, Li, Yousheng, Liang, Stephen Y., Loho, Tonny, Maegele, Marc, Malama, Sydney, Marei, Hany E., Martin-Loeches, Ignacio, Marwah, Sanjay, Massele, Amos, McFarlane, Michael, Melo, Renato Bessa, Negoi, Ionut, Nicolau, David P., Nord, Carl Erik, Ofori-Asenso, Richard, Omari, AbdelKarim H., Ordonez, Carlos A., Ouadii, Mouaqit, Pereira Junior, Gerson Alves, Piazza, Diego, Pupelis, Guntars, Rawson, Timothy Miles, Rems, Miran, Rizoli, Sandro, Rocha, Claudio, Sakakhushev, Boris, Sanchez-Garcia, Miguel, Sato, Norio, Lohse, Helmut A. Segovia, Sganga, Gabriele, Siribumrungwong, Boonying, Shelat, Vishal G., Soreide, Kjetil, Soto, Rodolfo, Talving, Peep, Tilsed, Jonathan V., Timsit, Jean-Francois, Trueba, Gabriel, Trung, Ngo Tat, Ulrych, Jan, van Goor, Harry, Vereczkei, Andras, Vohra, Ravinder S., Wani, Imtiaz, Uhl, Waldemar, Xiao, Yonghong, Yuan, Kuo-Ching, Zachariah, Sanoop K., Zahar, Jean-Ralph, Zakrison, Tanya L., Corcione, Antonio, Melotti, Rita M., Viscoli, Claudio and Viale, Perluigi (2016) Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA). World Journal of Emergency Surgery, 11 1: . doi:10.1186/s13017-016-0089-y
Roberts, Darren M., Ranganathan, Dwarakanathan, Wallis, Steven C., Varghese, Julie M., Kark, Adrian, Lipman, Jeffrey and Roberts, Jason A. (2016) Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis. Peritoneal Dialysis International, 36 4: 415-420. doi:10.3747/pdi.2015.00008
Ranganathan, Dwarakanathan, Naicker, Saiyuri, Wallis, Steven C., Lipman, Jeffrey, Ratanjee, Sharad K. and Roberts, Jason A. (2016) Stability of antibiotics for intraperitoneal administration in extraneal 7.5% icodextrin peritoneal dialysis bags (stab study). Peritoneal Dialysis International, 36 4: 421-426. doi:10.3747/pdi.2015.00062
Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016) Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 6: 872-879. doi:10.1002/bmc.3622
Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016) We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 1: . doi:10.1186/s13054-016-1348-8
Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016) Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 6: 436-438. doi:10.1016/j.ijantimicag.2016.02.017
Roger, Claire, Wallis, Steven C., Louart, Benjamin, Lefrant, Jean-Yves, Lipman, Jeffrey, Muller, Laurent and Roberts, Jason A. (2016) Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients. Journal of Antimicrobial Chemotherapy, 71 6: 1643-1650. doi:10.1093/jac/dkw043
Calandra, Thierry, Roberts, Jason A., Antonelli, Massimo, Bassetti, Matteo and Vincent, Jean-Louis (2016) Diagnosis and management of invasive candidiasis in the ICU: an updated approach to an old enemy. Critical Care, 20 1: . doi:10.1186/s13054-016-1313-6
Vincent, Jean-Louis, Bassetti, Matteo, Francois, Bruno, Karam, George, Chastre, Jean, Torres, Antoni, Roberts, Jason A., Taccone, Fabio S., Rello, Jordi, Calandra, Thierry, De Backer, Daniel, Welte, Tobias and Antonelli, Massimo (2016) Advances in antibiotic therapy in the critically ill. Critical Care, 20 1: . doi:10.1186/s13054-016-1285-6
Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016) Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 6: 601-614. doi:10.1080/17425255.2016.1178238
Jager, Nynke G., van Hest, Reinier M., Lipman, Jeffrey, Taccone, Fabio S. and Roberts, Jason A. (2016) Therapeutic drug monitoring of anti-infective agents in critically ill patients. Expert Review of Clinical Pharmacology, 9 7: 961-979. doi:10.1586/17512433.2016.1172209
Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016) A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 8: 1009-1017. doi:10.1093/cid/civ1199
Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016) The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 5: 667-678. doi:10.1517/14740338.2016.1164690
Alobaid, Abdulaziz S., Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio and Roberts, Jason A. (2016) Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review. International Journal of Antimicrobial Agents, 47 4: 259-268. doi:10.1016/j.ijantimicag.2016.01.009
Bellapart, Judith, Roberts, Jason Alexander, Appadurai, Vinesh, Wallis, Steven C., Nunez-Nunez, Maria and Boots, Robert James (2016) Pharmacokinetics of a novel dosing regimen of oral melatonin in critically ill patients. Clinical Chemistry and Laboratory Medicine, 54 3: 467-472. doi:10.1515/cclm-2015-0323
Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016) What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 3: 696-702. doi:10.1093/jac/dkv412
Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016) SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 1: 103.1-103.8. doi:10.1186/s12879-016-1421-6
Roberts, Jason A., Cotta, Menino Osbert, Cojutti, Piergiorgio, Lugano, Manuela, Rocca, Giorgio D. and Pea, Federico (2016) Does critical illness change levofloxacin pharmacokinetics?. Antimicrobial Agents and Chemotherapy, 60 3: 1459-1463. doi:10.1128/AAC.02610-15
Veringa, Anette, Sturkenboom, Marieke G. G., Dekkers, Bart G. J., Koster, Remco A., Roberts, Jason A., Peloquin, Charles A., Touw, Daan J. and Alffenaar, Jan-Willem C. (2016) LC-MS/MS for therapeutic drug monitoring of anti-infective drugs. Trends in Analytical Chemistry, 84 34-40. doi:10.1016/j.trac.2015.11.026
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016) In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 2: 827-832. doi:10.1128/AAC.02461-15
Delgado-Valverde, Mercedes, Torres, Eva, Valiente-Mendez, Adoracion, Almirante, Benito, Gomez-Zorrilla, Silvia, Borrell, Nuria, Corzo, Juan E., Gurgui, Mercedes, Almela, Manuel, Garcia-Alvarez, Lara, Fontecoba-Sanchez, Maria Crus, Martinez-Martinez, Luis, Canton, Rafael, Praena, Julia, Causse, Manuel, Gutierrez-Gutierrez, Belen, Roberts, Jason A., Farkas, Andras, Pascual, Alvaro, Rodriguez-Bano, Jesus, de Cueto, Marina, Planes Reig, Ana Maria, Quintano, Fe Tubau, Pena, Carmen, Galan Otalora, M. Elvira, Alegria, Carlos Ruiz de, Morosini, M. Isabel, Lepe, Jose Antonio, Cisneros, Jose Miguel, Morey, Shawna and Abdul-Aziz, Mohd-Hafiz (2016) Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project. Journal of Antimicrobial Chemotherapy, 71 2: 521-530. doi:10.1093/jac/dkv362
Roger, C., Muller, L., Wallis, S. C., Louart, B., Saissi, G., Lipman, J., Lefrant, J. Y. and Roberts, J. A. (2016) Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 71 2: 464-470. doi:10.1093/jac/dkv349
Sime, Fekade Bruck and Roberts, Jason A. (2016) Antibiotic dosing in critically ill patients receiving renal replacement therapy. Expert Review of Clinical Pharmacology, 9 4: 497-499. doi:10.1586/17512433.2016.1133290
Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016) Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 1-11. doi:10.1007/s00134-015-4188-0
Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016) Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 1: 206-214. doi:10.1128/AAC.01543-15
Roger, Claire, Nucci, Bastian, Louart, Benjamin, Friggeri, Arnaud, Knani, Haroun, Evrard, Alexandre, Lavigne, Jean-Philippe, Allaouchiche, Bernard, Lefrant, Jean-Yves, Roberts, Jason A. and Muller, Laurent (2016) Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis. Journal of Antimicrobial Chemotherapy, 71 1: 208-212. doi:10.1093/jac/dkv291
Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco, Gracia-Arnillas, Maria Pilar, Fernandez, Francisco, Feijoo, Neus, Bardolet, Neus, Rovira, Assumpta, Garro, Pau, Colon, Diana, Castillo, Carlos, Fernado, Juan, Lopez, Maria Jesus, Fernandez, Jose Luis, Arribas, Ana Maria, Teja, Jose Luis, Ots, Elsa, Montejo, Juan Carlos, Catalan, Marcedes, Prieto, Isidro, Gonzalo, Gloria, Galvan, Beatriz, Blasco, Miguel Ange, Meyer, Estibaliz, Nogal, Frutos Del, Vidaur, Loreto, Sebastian, Rosa, Garde, Pila Marco, Velasco, Maria del Mar Martin, Crespo, Rafael Zaragoza, Esperatti, Mariano, Torres, Antoni, Baldesi, Olivier, Dupont, Herve, Mahjoub, Yazine, Lasocki, Sigismond, Constantin, Jean Michel, Payen, Jean Francois, Albanese, Jacques, Malledant, Yannick, Pottecher, Julien, Lefrant, Jean-Yves, Jaber,Samir, Joannes-Boyau, Olivier, Orban,Christophe, Ostermann, Marlies, McKenzie, Catherine, Berry, Willaim, Smith, John, Lei, Katie, Rubulotta, Francesca, Gordon, Anthony, Brett, Stephen, Stotz, Martin, Templeton, Maie, Ebm, Claudia, Moran, Carl, Pettila, Ville, Xristodoulou, Aglaia, Theodorou, Vassiliki, Kouliatsis, Georgios, Sertaridou, Eleni, Anthopoulos, Georgios, Choutas, George, Rantis, Thanos, Karatzas, Stylianos, Balla, Margarita, Papanikolaou, Metaxia, Myrianthefs, Pavlos, Gavala, Alexandra, Fildisis, Georgios, Koutsoukou, Antonia, Kyriakopoulou, Magdalini, Petrochilou, Kalomoira, Kompoti, Maria, Michalia, Martha, Clouva-Molyvdas, Fillis-Maria, Gkiokas, Georgios, Nikolakopoulos, Fotios, Psychogiou, Vasiliki, Malliotakis, Polychronis, Akoumianaki, Evangelia, Lilitsis, Emmanouil, Koulouras, Vassilios, Nakos, George, Kalogirou, Mihalis, Komnos, Apostolos, Zafeiridis, Tilemachos, Chaintoutis, Christos, Arvaniti, Kostoula, Matamis, Dimitrios, Kydona, Christina, Gritsi-Gerogianni, Nikoleta, Giasnetsova, Tatiana, Giannakou, Maria, Soultati, Ioanna, Chytas, Ilias, Antoniadou, Eleni, Antipa, Elli, Lathyris, Dimitrios, Koukoubani,Triantafyllia, Paraforou, Theoniki, Spiropoulou, Kyriaki, Bekos, Vasileios, Spring, Anna, Kalatzi, Theodora, Nikolaou, Hara, Laskou, Maria, Strouvalis, Ioannis, Aloizos, Stavros, Kapogiannis, Spyridon, Soldatou, Ourania, Adembri, Chiara, Villa, Gianluca, Giarratano, Antonio, Raineri, Santi Maurizio, Cortegiani, Andrea, Montalto, Francesca, Strano, Maria Teresa, Ranieri, V. Marco, Sandroni, Claudio, De Pascale, Gennaro, Molin, Alexandre, Pelosi, Paolo, Montagnani, Luca, Urbino, Rosario, Mastromauro, Ilaria, De Rosa, Francesco G., Cardoso, Teresa, Afonso, Susana, Goncalves-Pereira, Joao, Baptista, Joao Pedro and Ozveren, Arife (2016) Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DA. Journal of Antimicrobial Chemotherapy, 71 1: 196-207. doi:10.1093/jac/dkv288
Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015) The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 12: . doi:10.1371/journal.pone.0144740
Shekar, Kiran, Roberts, Jason A., Barnett, Adrian G., Diab, Sara, Wallis, Steven C., Fung, Yoke L. and Fraser, John F. (2015) Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models. Critical Care, 19 1: 1-11. doi:10.1186/s13054-015-1151-y
Cotta, M. O., Roberts, J. A. and Lipman, J. (2015) Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 9: 563-572. doi:10.1016/j.medine.2015.07.001
Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate, Thomas, Karen, Bone, Allison, Cattigan, Claire, Elderkin, Tania, Salerno, Tania, Cameron, Robert, Ellis, Katrina, Hatter, Sheridan, Davis, Joshua, Sanap, Milind, Soar, Natalie, Wood, Josette, Chan, Karen, Heffernan, Aaron, Lai, Nai An, Moss, Catherine, Sheehy, Kate, Duroux, Maree, Ratcliffe, Megan, Shone, Samantha, Warhurst, Timothy, Dunlop, Rachel, Roberts, Jason, Stuart, Janine, Udy, Andrew, Cooper, David, McAllister, Rick, Cheng, Andrew, Inskip, Deborah, Miller, Jennene, Reynolds, Claire, Rudham, Sam, Baker, Stuart, Hepburn, Kristy, Roberts, Brigit, Woods, Paul, Chatterjee, Indranil, Smith, Judy, Cullen, Martin, Kong, Jing, Nayyar, Vineet, Leung, Patricia, Whitehead, Christina, Gilder, Eileen, McCarthy, Lianne, McGuiness, Shay, Parke, Rachael, Benefield, Kirsten, Chen, Yan, McArthur, Colin, Newby, Lynette, Henderson, Seton, Mehrtens, Jan, Noble, Sascha, Chadwick, Lesley, Freebain, Ross, Hogan, Chantal, Kazemi, Alex, Rust, Laura, Song, Rima, Tilsley, Anna, Williams, Anthony, Andrews, Lynn, Dinsdale, Richard, Hunt, Anna, Hurford, Sally, Mackle, Diane, Ongley, Jessica, Young, Paul, Durning, John, Frengley, Robert, La Pine, Mary, McCracken, Geoff, Sharma, Swarna Baskar, Kollef, Marin, Turnidge, John and Paul, Sanjoy (2015) A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 11: 1298-1305. doi:10.1164/rccm.201505-0857OC
Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015) Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 12: 3178-3183. doi:10.1093/jac/dkv201
Flores, Orlando, Stockton, Kellie, Roberts, Jason A., Muller, Michael J. and Paratz, Jennifer D. (2015) The efficacy and safety of adrenergic blockade post burn injury: a systematic review and meta-analysis. Journal of Trauma and Acute Care Surgery, 80 1: 146-155. doi:10.1097/TA.0000000000000887
Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015) A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115 509-514. doi:10.1016/j.jpba.2015.07.013
Sime, F. B., Roberts, M. S. and Roberts, J. A. (2015) Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21 10: 886-893. doi:10.1016/j.cmi.2015.05.002
Sime, Fekade B., Udy, Andrew A. and Roberts, Jason A. (2015) Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization. Current Opinion in Pharmacology, 24 1-6. doi:10.1016/j.coph.2015.06.002
Iyer, Kartik K., Roberts, James A., Hellstrom-Westas, Lena, Wikstrom, Sverre, Hansen Pupp, Ingrid, Ley, David, Breakspear, Michael and Vanhatalo, Sampsa (2015) Early detection of preterm intraventricular hemorrhage from clinical electroencephalography. Critical Care Medicine, 43 10: 2219-2227. doi:10.1097/CCM.0000000000001190
Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015) Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 10: 6471-6476. doi:10.1128/AAC.01321-15
Grau, S., Luque, S., Campillo, N., Samso, E., Rodriguez, U., Garcia-Bernedo, C.A., Salas, E., Sharma, R., Hope, W.W. and Roberts, J.A. (2015) Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis. Journal of Antimicrobial Chemotherapy, 70 10: 2854-2861. doi:10.1093/jac/dkv173
Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015) Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 19: 2585-2595. doi:10.4155/bio.15.173
Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015) Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 5: 412-420. doi:10.1097/MCC.0000000000000229
Parker, Suzanne L., Sime, Fekade B. and Roberts, Jason A. (2015) Optimizing dosing of antibiotics in critically ill patients. Current Opinion in Infectious Diseases, 28 6: 497-504. doi:10.1097/QCO.0000000000000206
Roberts, Jason A., Taccone, Fabio Silvio. and Lipman, Jeffrey. (2015) Understanding PK/PD. Intensive Care Medicine, 42 11: 1797-1800. doi:10.1007/s00134-015-4032-6
Hanrahan, T. P., Kotapati, C., Roberts, M. J., Rowland, J., Lipman, J., Roberts, J. A. and Udy, A. (2015) Factors associated with vancomycin nephrotoxicity in the critically ill. Anaesthesia and Intensive Care, 43 5: 594-599.
Hanrahan, Timothy, Whitehouse, Tony, Lipman, Jeffrey and Roberts, Jason A. (2015) Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion. International Journal of Antimicrobial Agents, 46 3: 249-253. doi:10.1016/j.ijantimicag.2015.04.013
Sime, Fekade Bruck., Roberts, Michael S., Tiong, Ing Soo., Gardner, Julia H., Lehman, Sheila., Peake, Sandra L., Hahn, Uwe., Warner, Morgyn S. and Roberts, Jason A. (2015) Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59 9: 5463-5469. doi:10.1128/AAC.00389-15
Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015) The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 9: 2671-2677. doi:10.1093/jac/dkv165
Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015) An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 18: 2311-2319. doi:10.4155/bio.15.143
Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015) A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 8: 4689-4694. doi:10.1128/AAC.00409-15
Coulter, Sonali, Merollini, Katharina, Roberts, Jason A., Graves, Nicholas and Halton, Kate (2015) The need for cost-effectiveness analyses of antimicrobial stewardship programmes: a structured review. International Journal of Antimicrobial Agents, 46 2: 140-149. doi:10.1016/j.ijantimicag.2015.04.007
Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015) Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 8: 419-424. doi:10.5301/ijao.5000422
Lipman, Jeffrey and Roberts, Jason (2015) Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 8: 1773-1774. doi:10.1097/CCM.0000000000001060
Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015) Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 4: 367-375. doi:10.1016/j.ijantimicag.2015.06.016
Roger, Claire, Nucci, Bastian, Molinari, Nicolas, Bastide, Sophie, Saissi, Gilbert, Pradel, Gael, Barbar, Saber, Aubert, Clement, Lloret, Sophie, Elotmani, Loubna, Polge, Anne, Lefrant, Jean-Yves, Roberts, Jason A and Muller, Laurent (2015) Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations. International Journal of Antimicrobial Agents, 46 1: 21-27. doi:10.1016/j.ijantimicag.2015.02.009
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015) Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 1: 121-124. doi:10.1016/j.ijantimicag.2015.02.017
Lopez-Garcia, Belen, Luque, Sonia, Roberts, Jason A. and Grau, Santiago (2015) Pharmacokinetics and preliminary safety ofhigh dose linezolid for the treatment of Gram-positive bacterial infections. Journal of Infection, 71 5: 604-607. doi:10.1016/j.jinf.2015.06.007
D'Agostino, Carly, Rhodes, Nathaniel J., Skoglund, Erik, Roberts, Jason A. and Scheetz, Marc H. (2015) Microbiologic clearance following transition from standard infusion piperacillin-tazobactam to extended-infusion for persistent Gram-negative bacteremia and possible endocarditis: a case report and review of the literature. Journal of Infection and Chemotherapy, 21 10: 742-746. doi:10.1016/j.jiac.2015.05.010
Brink, A. J., Richards, G. A., Lautenbach, E. E. G., Rapeport, N., Schillack, V., van Niekerk, L., Lipman, J. and Roberts, J. A. (2015) Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis. International Journal of Antimicrobial Agents, 45 6: 647-651. doi:10.1016/j.ijantimicag.2015.01.015
Sime, Fekade B., Roberts, Michael S., Tiong, Ing S., Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S. and Roberts, Jason A. (2015) Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70 8: 2369-2375. doi:10.1093/jac/dkv123
Jamal, Janattul-Ain, Mueller, Bruce A., Choi, Gordon Y. S., Lipman, Jeffrey and Roberts, Jason A. (2015) How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?. Diagnostic Microbiology and Infectious Disease, 82 1: 92-103. doi:10.1016/j.diagmicrobio.2015.01.013
Hanrahan, Timothy P., Harlow, Georgina, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2015) Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply. Critical Care Medicine, 43 5: E154-E155. doi:10.1097/CCM.0000000000000952
Shekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Ghassabian, Sussan, Anstey, Chris, Wallis, Steven C, Mullany, Daniel V, Fung, Yoke L and Fraser, John F (2015) Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study. Critical Care, 19 164: . doi:10.1186/s13054-015-0891-z
Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015) A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 84: . doi:10.1186/s13054-015-0818-8
Donadello, Katia, Antonucci, Elio, Cristallini, Stefano, Roberts, Jason A., Beumier, Marjorie, Scolletta, Sabino, Jacobs, Frederique, Rondelet, Benoit, de Backer, Daniel, Vincent, Jean-Louis and Taccone, Fabio Silvio (2015) β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study. International Journal of Antimicrobial Agents, 45 3: 278-282. doi:10.1016/j.ijantimicag.2014.11.005
Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015) Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 3: 1411-1417. doi:10.1128/AAC.04001-14
Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015) A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105 39-45. doi:10.1016/j.jpba.2014.11.042
Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015) Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 33: 1-7. doi:10.1186/s13054-015-0758-3
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015) Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 2: 192-195. doi:10.1016/j.ijantimicag.2014.08.013
Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015) Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 2: 528-533. doi:10.1093/jac/dku413
Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015) Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 1: 136-153. doi:10.1055/s-0034-1398490
Kanji S., Hayes M., Ling A., Shamseer L., Chant C., Edwards D.J., Edwards S., Ensom M.H.H., Foster D.R., Hardy B., Kiser T.H., La Porte C., Roberts J.A., Shulman R., Walker S., Zelenitsky S. and Moher D. (2015) Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement. Clinical Pharmacokinetics, 54 7: 783-795. doi:10.1007/s40262-015-0236-8
Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015) Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 28: 1-9. doi:10.1186/s13054-015-0750-y
Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015) Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 1: 24.1-24.8. doi:10.1186/s13063-014-0541-9
De Waele, J.J., Lipman, J., Carlier, M. and Roberts, J.A. (2015) Subtleties in practical application of prolonged infusion of β-lactam antibiotics. International Journal of Antimicrobial Agents, 45 5: 461-463. doi:10.1016/j.ijantimicag.2015.01.007
Roehr, Anka C., Frey, Otto R., Koeberer, Andreas, Fuchs, Thomas, Roberts, Jason A. and Brinkmann, Alexander (2015) Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside. International Journal of Artificial Organs, 38 1: 17-22. doi:10.5301/ijao.5000377
Carlier, Mieke, Taccone, Fabio S, Beumier, Majorie, Seyler, Lucie, Cotton, Frederic, Jacobs, Grederique and Roberts, Jason A (2015) Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy. International Journal of Antimicrobial Agents, 46 4: 413-419. doi:10.1016/j.ijantimicag.2015.05.020
Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015) Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 10: 739-742. doi:10.3109/23744235.2015.1021831
Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015) Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 45 1: 41-45. doi:10.1016/j.ijantimicag.2014.09.009
Orchard, Gregory R., Paratz, Jennifer D., Blot, Stijn and Roberts, Jason A. (2014) Risk factors in hospitalized patients with burn injuries for developing heterotopic ossification—a retrospective analysis. Journal of Burn Care and Research, 36 4: 465-470. doi:10.1097/BCR.0000000000000123
Shekar, Kiran, Fraser, John F., Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C., Mullany, Daniel V., Lipman, Jeffrey and Roberts, Jason A. (2014) The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study. Critical Care, 18 6: 1-9. doi:10.1186/s13054-014-0565-2
Baptista, Joao P., Roberts, Jason A., Sousa, Eduardo, Freitas, Ricardo, Deveza, Nuno and Pimentel, Jorge (2014) Decreasing the time to achieve therapeutic vancomycin concentrations in critically ill patients: Developing and testing of a dosing nomogram. Critical Care, 18 654: 1-9. doi:10.1186/s13054-014-0654-2
De Waele, J., Carlier, M., Hoste, E., Depuydt, P., Decruyenaere, J., Wallis, S. C., Lipman, J. and Roberts, J. A. (2014) Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis. Minerva Anestesiologica, 80 12: 1302-1309.
Chau, M. M., Kong, D. C. M., van Hal, S. J., Urbancic, K., Trubiano, J. A., Cassumbhoy, M., Wilkes, J., Cooper, C. M., Roberts, J. A., Marriott, D. J. E. and Worth, L. J. (2014) Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014. Internal Medicine Journal, 44 12: 1364-1388. doi:10.1111/imj.12600
Roberts, Jason A. (2014) Therapeutic drug monitoring of antibiotics – author's reply. Lancet Infectious Diseases, 14 12: 1181-1181. doi:10.1016/S1473-3099(14)71007-2
Hanrahan, Timothy P., Harlow, Georgina, Hutchinson, James, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2014) Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis. Critical Care Medicine, 42 12: 2527-2536. doi:10.1097/CCM.0000000000000514
Udy, Andrew A., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2014) Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds. Critical Care, 18 657: 1-9. doi:10.1186/s13054-014-0657-z
Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014) How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 288: 1-11. doi:10.1186/1471-2334-14-288
Donadello, Katia, Roberts, Jason A., Cristallini, Stefano, Beumier, Marjorie, Shekar, Kiran, Jacobs, Frederique, Belhaj, Asmae, Vincent, Jean-Louis, de Backer, Daniel and Taccone, Fabio Silvio (2014) Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study. Critical Care, 18 632: 1-10. doi:10.1186/s13054-014-0632-8
Tsai, Danny, Jamal, Janattul-Ain, Davis, Joshua S., Lipman, Jeffrey and Roberts, Jason A. (2014) Interethnic differences in pharmacokinetics of antibacterials. Clinical Pharmacokinetics, 54 3: 243-260. doi:10.1007/s40262-014-0209-3
Adnan, S., Ratnam, S., Kumar, S., Paterson, D., Lipman, J., Roberts, J. and Udy, A. A. (2014) Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit. Anaesthesia And Intensive Care, 42 6: 715-722.
Roberts, Jason A. and Fraser, John F. (2014) Meeting the challenges of advanced drug delivery in critical illness. Advanced Drug Delivery Reviews, 77 1-2. doi:10.1016/j.addr.2014.11.002
Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014) Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 10: 1380-1384. doi:10.1177/1060028014540610
Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014) Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 10: 2797-2803. doi:10.1093/jac/dku195
Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014) Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 6: 907-908. doi:10.1093/cid/ciu403
Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014) Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 5: 409-415. doi:10.1016/j.ijantimicag.2014.07.001
Felton, T. W., Hope, W. W. and Roberts, J. A. (2014) How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?. Diagnostic Microbiology and Infectious Disease, 79 4: 441-447. doi:10.1016/j.diagmicrobio.2014.04.007
Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014) The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 7: 1640-1650. doi:10.1097/CCM.0000000000000317
De Rosa, Francesco G. and Roberts, Jason A. (2014) Amikacin dosing in the ICU: we now know more, but still not enough .... Intensive Care Medicine, 40 7: 1033-1035. doi:10.1007/s00134-014-3308-6
Maseda, Emilio, Grau, Santiago, Villagran, Maria-Jose, Hernandez-Gancedo, Carmen, Lopez-Tofino, Araceli, Roberts, Jason A., Aguilar, Lorenzo, Luque, Sonia, Sevillano, David, Gimenez, Maria-Jose and Gilsanz, Fernando (2014) Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration. Journal of Antimicrobial Chemotherapy, 69 6: 1624-1632. doi:10.1093/jac/dku013
Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014) Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960 134-144. doi:10.1016/j.jchromb.2014.04.029
Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014) Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 6: 572-573. doi:10.1016/j.ijantimicag.2014.03.001
Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014) Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 3: 1-11. doi:10.1186/cc13874
Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014) Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 5: 1495-1502. doi:10.1093/jac/dku564
Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014) An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 5: 1416-1423. doi:10.1093/jac/dkt523
Blot,Stijn, Lipman, Jeffrey, Roberts, Darren M. and Roberts, Jason A (2014) The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?. Diagnostic Microbiology and Infectious Disease, 79 1: 77-84. doi:10.1016/j.diagmicrobio.2014.01.015
Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014) DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 8: 1072-1083. doi:10.1093/cid/ciu027
Smits, Anne, Roberts, Jason A., Vella-Brincat, Jane W. A. and Allegaert, Karel (2014) Cefazolin plasma protein binding in different human populations: More than cefazolin-albumin interaction. International Journal of Antimicrobial Agents, 43 2: 199-200. doi:10.1016/j.ijantimicag.2013.10.008
Avent, Minyon L., Hall, Lisa, Davis, Louise, Allen, Michelle, Roberts, Jason A., Unwin, Sean, McIntosh, Kylie A., Thursky, Karin, Buising, Kirsty and Paterson, David L. (2014) Antimicrobial stewardship activities: a survey of Queensland hospitals. Australian Health Review, 38 5: 557-563. doi:10.1071/AH13137
Roberts, Jason A., Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander ., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely, Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula and Kuti, Joseph L. (2014) Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. The Lancet Infectious Diseases, 14 6: 498-509. doi:10.1016/S1473-3099(14)70036-2
Felton, T. W., Roberts, J. A., Lodise, T. P., Van Guilder, M., Boselli, E., Neely, M. N. and Hope, W. W. (2014) Individualization of piperacillin dosing for critically ill patients: Dosing software to optimize antimicrobial therapy. Antimicrobial Agents and Chemotherapy, 58 7: 4094-4102. doi:10.1128/AAC.02664-14
Roberts, Jason A., Udy, Andrew A., Bulitta, Juergen B., Stuart, Janin, Jarrett, Paul, Starr, Therese, Lassig-Smith, Melissa, Roberts, Natasha A., Dunlop, Rachel, Hayashi, Yoshiro, Wallis, Steven C. and Lipman, Jeffrey (2014) Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 69 9: 2508-2516. doi:10.1093/jac/dku177
Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014) Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 6: 3533-3537. doi:10.1128/AAC.02340-14
Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014) Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 5: 423-430. doi:10.1016/j.ijantimicag.2014.01.023
Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014) Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 5: 581-595. doi:10.1586/14787210.2014.902308
Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014) A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units. Nephrology, 19 8: 507-512. doi:10.1111/nep.12276
Escobar, Leslie, Andresen, Max, Downey, Patricio, Gai, Maria Nella, Regueira, Tomas, Borquez, Tamara, Lipman, Jeffrey and Roberts, Jason A. (2014) Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume haemofiltration. International Journal of Antimicrobial Agents, 44 2: 163-167. doi:10.1016/j.ijantimicag.2014.03.009
Varghese, Julie M., Jarrett, Paul, Boots, Robert J., Kirkpatrick, Carl M. J., Lipman, Jeffrey and Roberts, Jason A. (2014) Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 43 4: 343-348. doi:10.1016/j.ijantimicag.2014.01.009
De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C. and Roberts, J. A. (2014) Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 40 9: 1340-1351. doi:10.1007/s00134-014-3403-8
Roberts, Jason A. and Roberts, Darren M. (2014) Antibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines?. Critical Care, 18 3: . doi:10.1186/cc13939
Shekar, Kiran, Fraser, John F. and Roberts, Jason A. (2013) Can optimal drug dosing during ECMO improve outcomes?. Intensive Care Medicine, 39 12: 2237-2237. doi:10.1007/s00134-013-3080-z
Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013) Clinical implications of antibiotic pharmacokinetic principles in the critically ill. Intensive Care Medicine, 39 12: 2070-2082. doi:10.1007/s00134-013-3088-4
Adnan, Syamhanin, Paterson, David L., Lipman, Jeffrey and Roberts, Jason A. (2013) Ampicillin/sulbactam: Its potential use in treating infections in critically ill patients. International Journal of Antimicrobial Agents, 42 5: 384-389. doi:10.1016/j.ijantimicag.2013.07.012
Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013) What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 4: 289-293. doi:10.1016/j.ijantimicag.2013.05.018
Putt, M. T., Udy, A. A., Jarrett, P., Martin, J., Hennig, S., Salmon, N., Lipman, J. and Roberts, J. A. (2013) Phenytoin loading doses in adult critical care patients: does current practice achieve adequate drug levels?. Anaesthesia and Intensive Care, 41 5: 602-609.
Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Udy, Andrew A., Paul, Sanjoy K. and Lipman, Jeffrey (2013) A protocol for a multicentre randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis: the BLING II study. Critical Care and Resuscitation, 15 3: 179-185.
Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L. and Lipman, Jeffrey (2013) Reply to Soman et al. Clinical Infectious Diseases, 57 2: 323-324. doi:10.1093/cid/cit201
Adnan, Syamhanin, Li, Janice Xuanhui, Wallis, Steven C., Rudd, Michael, Jarrett, Paul, Paterson, David L., Lipman, Jeffrey, Udy, Andrew A. and Roberts, Jason A. (2013) Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains. International Journal of Antimicrobial Agents, 42 1: 90-93. doi:10.1016/j.ijantimicag.2013.02.023
Udy, Andrew A., Covajes, Cecilia, Taccone, Fabio Silvio, Jacobs, Frederique, Vincent, Jean-Louis, Lipman, Jeffrey and Roberts, Jason A. (2013) Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?. International Journal of Antimicrobial Agents, 41 6: 564-568. doi:10.1016/j.ijantimicag.2013.01.018
Carlier, Mieke, Carrette, Sofie, Roberts, Jason A., Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C. and De Waele, Jan J. (2013) Meropenem and piperacillin/tazobactam prescribing in critically ill patients: Does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?. Critical Care, 17 3: R84.1-R84.9. doi:10.1186/cc12705
Mrara, B., Roberts, J. A. and Gowardman, J. (2013) Digoxin prescription in the critically ill: an unpredictably loaded problem?. Anaesthesia and Intensive Care, 41 3: 434-436.
Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013) How should we dose antibiotics for pneumonia in the ICU?. Current Opinions in Infectious Diseases, 26 2: 189-195. doi:10.1097/QCO.0b013e32835d19e0
Shekar, Kiran, Roberts, Jason A., Smith, Maree T., Fung, Yoke L. and Fraser, John F. (2013) The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation. BMC Anesthesiology, 13 7.1-7.10. doi:10.1186/1471-2253-13-7
Hayashi, Yoshiro, Lipman, Jeffrey, Udy, Andrew A., Ng, Mandy, McWhinney, Brett, Ungerer, Jacobus, Lust, Karin and Roberts, Jason A. (2013) β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia. International Journal of Antimicrobial Agents, 41 2: 162-166. doi:10.1016/j.ijantimicag.2012.10.002
Roberts, Jason and Lipman, Jeffrey (2013) Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance and decreased bacterial susceptibility. Critical Care Medicine, 41 2: 489-495. doi:10.1097/CCM.0b013e31826ab4c4
Semark, Andrew J., Venkatesh, Karthik, McWhinney, Brett C., Pretorius, Carel, Roberts, Jason A., Cohen, Jeremy and Venkatesh, Bala (2013) The compatibility of a low concentration of hydrocortisone sodium succinate with selected drugs during a simulated Y-site administration. Critical Care and Resuscitation, 15 1: 63-66.
Wong, Gloria, Briscoe, Scott, Adnan, Syamhanin, McWhinney, Brett, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2013) Protein binding of β-lactam antibiotics in critically Ill patients: can we successfully predict unbound concentrations?. Antimicrobial Agents and Chemotherapy, 57 12: 6165-6170. doi:10.1128/AAC.00951-13
Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Lipman, Jeffrey and Roberts, Jason A. (2013) Defining antibiotic dosing in lung infections. Clinical Pulmonary Medicine, 20 3: 121-128. doi:10.1097/CPM.0b013e31828fc646
Beumier, Marjorie, Roberts, Jason A., Kabtouri, Hakim, Hites, Maya, Cotton, Frederic, Wolff, Fleur, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis and Taccone, Fabio Silvio (2013) A new regimen for continuous infusion of vancomycin during continuous renal replacement therapy. Journal of Antimicrobial Chemotherapy, 68 12: 2859-2865. doi:10.1093/jac/dkt261
Ranganathan,Dwarakanathan, John, George T., Healy, Helen, Roberts, Matthew J., Fassett, Robert G., Lipman, Jeffrey, Kubler, Paul, Ungerer, Jacobus, McWhinney, Brett C., Lim, Aaron, Purvey, Megan, Reyaldeen, Reza and Roberts, Jason A. (2013) A protocol for the pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN): An open-label, randomised controlled trial. BMJ Open, 3 8: . doi:10.1136/bmjopen-2013-003511
Carlier, Mieke, Noe, Michael, De Waele, Jan J., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2013) Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients. Journal of Antimicrobial Chemotherapy, 68 11: 2600-2608. doi:10.1093/jac/dkt240
Dulhunty, Joel M., Roberts, Jason A., Webb, Joshua S., Webb, Steve A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David and Lipman, Jeffrey (2013) Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicentre double-blind, randomised controlled trial.. Clinical Infectious Diseases, 56 2: 236-244. doi:10.1093/cid/cis856
Roberts, Jason, Pea, Federico and Lipman, Jeffrey (2013) The clinical relevance of plasma protein binding changes. Clinical Pharmacokinetics, 52 1: 1-8. doi:10.1007/s40262-012-0018-5
Udy, Andrew A., Roberts, Jason A., Shorr, Andrew F., Boots, Robert J. and Lipman, Jeffrey (2013) Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients. Critical Care, 17 1: R35.1-R35.9. doi:10.1186/cc12544
Smith, Nicholas L., Freebairn, Ross C., Park, Michael A. J., Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2012) Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime. Critical Care and Resuscitation, 14 4: 312-315.
Abbott, Iain J. and Roberts, Jason A. (2012) Infusional beta-lactam antibiotics in febrile neutropenia: has the time come?. Current Opinion in Infectious Diseases, 25 6: 619-625. doi:10.1097/QCO.0b013e32835915c2
Shekar, Kiran, Roberts, Jason A., Welsh, Susan, Buscher, Hergen, Rudham, Sam, Burrows, Fay, Ghassabian, Sussan, Wallis, Steven C., Levkovich, Bianca, Pellegrino, Vin, McGuiness, Shay, Parke, Rachael, Gilder, Eileen, Barnett, Adrian G., Walsham, James, Mullany, Daniel V., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012) ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO. BMC Anesthesiology, 12 29.1-29.9. doi:10.1186/1471-2253-12-29
Shekar, K., Roberts, J. A., Ghassabian, S., Mullany, D. V., Ziegenfuss, M., Smith, M. T., Fung, Y. L. and Fraser, J. F. (2012) Sedation during extracorporeal membrane oxygenation-why more is less. Anaesthesia and Intensive Care, 40 6: 1067-1069.
Carlier, Mieke, Stove, Veronique, Roberts, Jason A., Van de Velde, Eric, De Waele, Jan J. and Verstraete, Alain G. (2012) Quantification of seven beta-lactam antibiotics and two beta-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method. International Journal of Antimicrobial Agents, 40 5: 416-422. doi:10.1016/j.ijantimicag.2012.06.022
Shekar, Kiran, Roberts, Jason A., Ghassabian, Sussan, Mullany, Daniel V., Wallis, Steven C., Smith, Maree T. and Fraser, John F. (2012) Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?. Journal of Antimicrobial Chemotherapy, 68 3: 726-727. doi:10.1093/jac/dks435
Shekar, Kiran, Roberts, Jason A., McDonald, Charles I., Fisquet, Stephanie, Barnett, Adrian G., Mullany, Daniel V., Ghassabian, Sussan, Wallis, Steven C., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012) Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation. Critical Care, 16 5: R194.1-R194.7. doi:10.1186/cc11679
Briscoe, Scott E., McWhinney, Brett C., Lipman, Jeffrey, Roberts, Jason A. and Ungerer, Jacobus P. J. (2012) A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 907 178-184. doi:10.1016/j.jchromb.2012.09.016
Jamal, Janattul-Ain, Economou, Caleb J. P., Lipman, Jeffrey and Roberts, Jason A. (2012) Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation. Current Opinion in Critical Care, 18 5: 460-471. doi:10.1097/MCC.0b013e32835685ad
Abdul-Aziz, Mohd H., Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey and Roberts, Jason A. (2012) Continuous beta-lactam infusion in critically ill patients: the clinical evidence. Annals of Intensive Care, 2 1: . doi:10.1186/2110-5820-2-37
Varghese, Julie M., Roberts, Jason A., Wallis, Steven C., Boots, Robert J., Healy, Helen, Fassett, Robert G., Lipman, Jeffrey and Ranganathan, Dwarakanathan (2012) Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study). Clinical Journal of the American Society of Nephrology, 7 8: 1249-1256. doi:10.2215/CJN.12211211
Patel, Bhavik M., Paratz, Jennifer D., Mallet, Anthony, Lipman, Jeffrey, Rudd, Michael, Muller, Michael J., Paterson, David L. and Roberts, Jason A. (2012) Characteristics of bloodstream infections in burn patients: an 11-year retrospective study. Burns, 38 5: 685-690. doi:10.1016/j.burns.2011.12.018
Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012) Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 1: 35.1-35.11. doi:10.1186/2110-5820-2-35
Roberts, Jason, De Waele, Jan J., Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven and Lipman, Jeffrey (2012) DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic. BMC Infectious Diseases, 12 152.1-152.7. doi:10.1186/1471-2334-12-152
Udy, Andrew A., Varghese, Julie M., Altukroni, Mahdi, Briscoe, Scott, McWhinney, Brett C., Ungerer, Jacobus P., Lipman, Jeffrey and Roberts, Jason A. (2012) Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations. Chest, 142 1: 30-39. doi:10.1378/chest.11-1671
Kaur, Sukhpreet, Roberts, Jason A. and Roberts, Michael S. (2012) Evaluation of medication-related problems in medication reviews: a comparative perspective. Annals of Pharmacotherapy, 46 7-8: 972-982. doi:10.1345/aph.1Q694
Roberts, Jason A. and Lipman, Jeffrey (2012) Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling. Clinical Infectious Diseases, 54 12: 1727-1729. doi:10.1093/cid/cis311
Shekar, Kiran, Fung, Yoke L., Diab, Sara, Mullany, Daniel V., McDonald, Charles I, Dunster, Kimble R., Fisquet, Kimble R, Platts, David G., Stewart, David G, Wallis, Steven C., Smith, Maree T., Roberts, Jason A. and Fraser, John F. (2012) Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions. Critical Care and Resuscitation, 14 2: 105-111.
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012) beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 6: 489-496. doi:10.1111/j.1440-1681.2012.05715.x
Udy, Andrew A., Roberts, Jason A., De Waele, Jan J., Paterson, David L. and Lipman, Jeffrey (2012) What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance. International Journal of Antimicrobial Agents, 39 6: 455-457. doi:10.1016/j.ijantimicag.2012.02.010
Dhanani, Jayesg, Roberts, Jason A. and Lipman, Jeffrey (2012) Antibiotic therapy of pneumonia in critical care. Current Respiratory Medicine Reviews, 8 3: 228-238. doi:10.2174/157339812800493232
Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012) Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 5: 1523-1528. doi:10.1097/CCM.0b013e318241e553
Patel, Bhavik M., Paratz, Jennifer, See, Natalie C., Muller, Michael J., Rudd, Michael, Paterson, David, Briscoe, Scott E., Ungerer, Jacobus, McWhinney, Brett C., Lipman, Jeffrey and Roberts, Jason A. (2012) Therapeutic drug monitoring of beta-lactam antibiotics in burns patients-A one-year prospective study. Therapeutic Drug Monitoring, 34 2: 160-164. doi:10.1097/FTD.0b013e31824981a6
Adnan, Syamhanin, Paterson, David, Lipman, Jeffrey, Kumar, Suresh, Li, Janice, Rudd, Michael J and Roberts, Jason (2012) Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal pathologies: A structured review. Surgical Infections, 13 1: 9-17. doi:10.1089/sur.2011.046
Roberts, Jason A., Joynt, Gavin M., Choi, Gordon Y.S., Gomersall, Charles D. and Lipman, Jeffrey (2012) How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics. International Journal of Antimicrobial Agents, 39 3: 187-192. doi:10.1016/j.ijantimicag.2011.11.002
Roberts, Jason (2012) Australian clinical pharmacy award oration. Journal of Pharmacy Practice and Research, 42 4: 308-310.
Shekar, K., Roberts, J. A., Mullany, D. V., Corley, A., Fisquet, S., Bull, T. N., Barnett, A. G. and Fraser, J. F. (2012) Increased sedation requirements in patients receiving extracorporeal membrane oxygenation for respiratory and cardiorespiratory failure. Anaesthesia and Intensive Care, 40 4: 648-655.
Abdul-Aziz, Mohd Hafiz, Staatz, C. E., Kirkpatrick, C. M. J., Lipman, J. and Roberts, J. A. (2012) Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics. Minerva Anestesiologica, 78 1: 94-104.
Roberts, Jason A., Norris, Ross, Paterson, David L. and Martin, Jennifer H. (2012) Therapeutic drug monitoring of antimicrobials. British Journal of Clinical Pharmacology, 73 1: 27-36. doi:10.1111/j.1365-2125.2011.04080.x
Shekar, Kiran, Fraser, John F., Smith, Maree T. and Roberts, Jason A. (2012) Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation. Journal of Critical Care, 27 6: 741.e9-741.e18. doi:10.1016/j.jcrc.2012.02.013
Lonsdale, Dagan O., Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2012) Antibacterial therapeutic drug monitoring in cerebrospinal fluid: difficulty in achieving adequate drug concentrations. Journal of Neurosurgery, 118 2: 297-301. doi:10.3171/2012.10.JNS12883
Li, Janice, Udy, Andrew A., Kirkpatrick, Carl M.J., Lipman, Jeffrey and Roberts,Jason A. (2012) Improving vancomycin prescription in critical illness through a drug use evaluation process: a weight-based dosing intervention study. International Journal of Antimicrobial Agents, 39 1: 69-72. doi:10.1016/j.ijantimicag.2011.08.017
Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012) Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 1: 1-10. doi:10.1016/j.ijantimicag.2011.07.013
Patel, Kashyap, Roberts, Jason A., Lipman, Jeffrey, Tett, Susan E., Deldot, Megan E. and Kirkpatrick, Carl M. (2011) Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration - using Monte Carlo Simulations to predict doses for specified pharmacodynamic targets. Antimicrobial Agents and Chemotherapy, 55 12: 5868-5873. doi:10.1128/AAC.00424-11
Roberts, Jason A. (2011) Using PK/PD to Optimize Antibiotic Dosing for Critically Ill Patients. Current Pharmaceutical Biotechnology, 12 12: 2070-2079. doi:10.2174/138920111798808329
Roberts, Jason A. (2011) Importance of Antibiotic Dosing in Critically Ill Patients. Current Pharmaceutical Biotechnology, 12 12: 1981-1982. doi:10.2174/138920111798808310
Lipman, J., Udy, A. and Roberts, Jason (2011) Do we understand the impact of altered physiology, consequent interventions and resultant clinical scenarios in the intensive care unit? The antibiotic story. Anaesthesia and Intensive Care, 39 6: 999-1000.
Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011) Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 11: 5238-5242. doi:10.1128/AAC.05033-11
Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011) Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 11: 1431-1440. doi:10.1517/17425255.2011.615309
Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2011) Implications of augmented renal clearance in critically ill patients. Nature Reviews Nephrology, 7 9: 539-543. doi:10.1038/nrneph.2011.92
Martin, Jennifer H., Fay, Michael F., Udy, Andrew, Roberts, Jason, Kirkpatrick, Carl, Ungerer, Jacobus and Lipman, Jeffrey (2011) Pitfalls of using estimations of glomerular filtration rate in an intensive care population. Internal Medicine Journal, 41 7: 537-543. doi:10.1111/j.1445-5994.2009.02160.x
Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew A., Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2011) Vancomycin Dosing in Critically Ill Patients: Robust Methods for Improved Continuous-Infusion Regimens. Antimicrobial Agents and Chemotherapy, 55 6: 2704-2709. doi:10.1128/AAC.01708-10
Baptista, Joao P., Udy, Andrew A., Sousa, Eduardo, Pimentel, Jorge, Wang, Lisa, Roberts, Jason A. and Lipman, Jeffrey (2011) A comparison of estimates of glomerular filtration in critically ill patients with augmented renal clearance. Critical Care, 15 3: 1-8. doi:10.1186/cc10262
Ulldemolins, Marta, Roberts, Jason A., Lipman, Jeffrey and Rello, Jordi (2011) Antibiotic dosing in multiple organ dysfunction syndrome. Chest, 139 5: 1210-1220. doi:10.1378/chest.10-2371
Roberts, Jason A., Mehta, Ravindra L. and Lipman, Jeffrey (2011) Sustained low efficiency dialysis allows rational renal replacement therapy, but does it allow rational drug dosing?. Critical Care Medicine, 39 3: 602-603. doi:10.1097/CCM.0b013e31820e6a0d
Roberts, Jason A., Kwa, Andrea, Montakantikul, Preecha, Gomersall, Charles, Kuti, Joseph L. and Nicolau, David P. (2011) Pharmacodynamic profiling of intravenous antibiotics against prevalent Gram-negative organisms across the globe: The PASSPORT Program—Asia-Pacific Region. International Journal of Antimicrobial Agents, 37 3: 225-229. doi:10.1016/j.ijantimicag.2010.10.024
Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011) Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 3.1-3.7. doi:10.1186/1471-2253-11-3
Ulldemolins, Marta, Roberts, Jason A., Rello, Jordi, Paterson, David L. and Lipman, Jeffrey (2011) The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clinical Pharmacokinetics, 50 2: 99-110. doi:10.2165/11539220-000000000-00000
Roberts, Jason, Kirkpatrick, Carl M.J. and Lipman, Jeffrey (2011) Monte Carlo simulations: Maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients. Journal of Antimicrobial Chemotherapy, 66 2: 227-231. doi:10.1093/jac/dkq449
McGloughlin, Steven, Roberts, Jason A., O'Donoghue, Steven, Martin, Jennifer, Briscoe, Scott and Lipman, Jeffrey (2011) Ganciclovir pharmacokinetics and suggested dosing in continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 37 1: 90-92. doi:10.1016/j.ijantimicag.2010.10.003
Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011) The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 5.1-5.5. doi:10.1186/1471-2253-11-5
Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2011) Antimicrobial Pharmacokinetic and Pharmacodynamic Issues in the Critically Ill with Severe Sepsis and Septic Shock. Critical Care Clinics, 27 1: 19-34. doi:10.1016/j.ccc.2010.09.006
Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy, Banks, Merrilyn, Dulhunty, Joel, Roberts, Jason A. and Lipman, Jeffrey (2011) Effect of intravenous GLutamine supplementation in Trauma patients receiving enteral nutrition study protocol (GLINT Study): A prospective, blinded, randomised, placebo-controlled clinical trial. BMJ Open, 1 2: 1-8. doi:10.1136/bmjopen-2011-000334
Dhanani, Jayesh, Roberts, Jason A., Chew, Michelle, Lipman, Jeffrey, Boots, Robert J., Paterson, David L. and Fraser, John F. (2010) Antimicrobial chemotherapy and lung microdialysis: a review. International Journal of Antimicrobial Agents, 36 6: 491-500. doi:10.1016/j.ijantimicag.2010.08.013
Roberts, Jason, Boots, Robert J. and Lipman, Jeffrey (2010) Optimal antibiotic therapy in the management of the lung of the critically ill. Current Reviews in Respiratory Medicine, 6 4: 253-263. doi:10.2174/157339810793563749
Roberts, Jason A., Ulldemolins, Marta, Roberts, Michael S., McWhinney, Brett, Ungerer, Jacobus, Paterson, David L. and Lipman, Jeffrey (2010) Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept. International Journal of Antimicrobial Agents, 36 4: 332-339. doi:10.1016/j.ijantimicag.2010.06.008
Dulhunty, Joel, Webb, Steven, Paterson, David, Bellomo, Rinaldo, Myburgh, John, Roberts, Jason and Lipman, Jeffrey (2010) A survey of antibiotic prescribing practices in Australian and New Zealand intensive care units. Critical Care and Resuscitation, 12 3: 162-170.
Roberts, Jason A., Field, Jonathan, Visser, Adam, Whitbread, Rosemary, Tallot, Mandy, Lipman, Jeffrey and Kirkpatrick, Carl M. J. (2010) Using population pharmacokinetics to determine Gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. Antimicrobial Agents and Chemotherapy, 54 9: 3635-3640. doi:10.1128/AAC.00222-10
Ulldemolins, Marta, Roberts, Jason A., Wallis, Steven C., Rello, Jordi and Lipman, Jeffrey (2010) Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: Special emphasis on unbound pharmacokinetics. Journal of Antimicrobial Chemotherapy, 65 8: 1771-1778. doi:10.1093/jac/dkq184
Hayashi, Yoshiro, Roberts, Jason A., Paterson, David L. and Lipman, Jeffrey (2010) Pharmacokinetic evaluation of piperacillin-tazobactam. Expert Opinion on Drug Metabolism and Toxicology, 6 8: 1017-1031. doi:10.1517/17425255.2010.506187
Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2010) Pharmacokinetics and pharmacodynamics in critically ill patients. Current Opinion in Anesthesiology, 23 4: 472-478. doi:10.1097/ACO.0b013e328339ef0a
Ulldemolins, Marta, Roberts, Jason A. and Lipman, Jeffrey (2010) Optimizing antibiotic use in the intensive care unit. Clinical Pulmonary Medicine, 17 4: 162-169. doi:10.1097/CPM.0b013e3181e47953
Bilgrami, I., Roberts, J. A., Wallis, S. C., Thomas, J., Davis, J., Fowler, S., Goldrick, P. B. and Lipman, J. (2010) Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration. Antimicrobial Agents and Chemotherapy, 54 7: 2974-2978. doi:10.1128/AAC.01582-09
McWhinney, Brett C., Wallis, Steven C., Hillister, Tara, Roberts, Jason A., Lipman, Jeffrey and Ungerer, Jacobus P.J. (2010) Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 22: 2039-2043. doi:10.1016/j.jchromb.2010.05.027
Udy, Andrew A., Putt, Michael T., Shanmugathasan, Sulochana, Roberts, Jason A. and Lipman, Jeffrey (2010) Augmented renal clearance in the Intensive Care Unit: An illustrative case series. International Journal of Antimicrobial Agents, 35 6: 606-608. doi:10.1016/j.ijantimicag.2010.02.013
Roberts, Jason A., Ulldemolins, Marta and Lipman, Jeffrey (2010) Meropenem: Focus on its use in serious bacterial infections. Clinical Medicine Reviews in Therapeutics, 2 1-14. doi:10.4137/CMRT.S4598
Roberts, Jason A., Hope, William W. and Lipman, Jeffrey (2010) Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?. International Journal of Antimicrobial Agents, 35 5: 419-420. doi:10.1016/j.ijantimicag.2010.01.022
Martin, Jennifer H., Norris, Ross, Barras, Michael, Roberts, Jason, Morris, Ray, Doogue, Matthew and Jones, Graham R. D. (2010) Therapeutic monitoring of vancomycin in adult patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Clinical Biochemist Reviews, 31 1: 21-24.
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010) First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 2: 156-163. doi:10.1016/j.ijantimicag.2009.10.008
Udy, Andrew A., Roberts, Jason A., Boots, Robert J., Paterson, David L. and Lipman, Jeffrey (2010) Augmented renal clearance: Implications for antibacterial dosing in the critically Ill. Clinical Pharmacokinetics, 49 1: 1-16. doi:10.2165/11318140-000000000-00000
Ranganathan, Dwarakanathan, Varghese, Julie M., Fassett, Robert G., Lipman, Jeffrey, D'Intini, Vincent, Healy, Helen and Roberts, Jason A. (2009) Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study. BMC Nephrology, 10 1: 1-6. doi:10.1186/1471-2369-10-42
Roberts, Jason A., Udy, Andrew A., O'Donoghue, Stephen, Briscoe, Scott, Paterson, David L. and Lipman, Jeffrey (2009) Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis. International Journal of Antimicrobial Agents, 34 4: 383-384. doi:10.1016/j.ijantimicag.2009.05.005
Roberts, Jason A., Coulthard, Mark G., Addison, Russell S., Foot, Carole and Lipman, Jeffrey (2009) Midazolam metabolism: Implications for individualised dosing?. Journal of Pharmacy Practice and Research, 39 3: 198-201.
Roberts, JA and Lipman, J (2009) Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing. Journal of Pharmacy Practice and Research, 39 3: 219-222.
Roberts, Jason A. and Lipman, Jeffrey (2009) Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy. Critical Care Medicine, 37 8: 2491-2492. doi:10.1097/CCM.0b013e3181aee840
Roberts, Jason A., Webb, Steven, Paterson, David, Ho, Kwok M. and Lipman, Jeffrey (2009) A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics. Critical Care Medicine, 37 6: 2071-2078. doi:10.1097/CCM.0b013e3181a0054d
Roberts, Jason A. and Lipman, Jeffrey (2009) Pharmacokinetic issues for antibiotics in the critically ill patient. Critical Care Medicine, 37 3: 840-851. doi:10.1097/CCM.0b013e3181961bff
Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009) Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 3: 926-933. doi:10.1097/CCM.0b013e3181968e44
Udy, A., Roberts, J. A., Boots, R. J. and Lipman, J. (2009) You only find what you look for: The importance of high creatinine clearance in the critically ill. Anaesthesia and Intensive Care, 37 1: 11-13.
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009) Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 1: 142-150. doi:10.1093/jac/dkp139
Roberts, Jason A, Lipman, Jeffrey, Blot, Stijn and Rello, Jordi (2008) Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?. Current Opinion in Critical Care, 14 4: 390-396. doi:10.1097/MCC.0b013e3283021b3a
Roberts, Jason A., Kruger, Peter, Paterson, David L. and Lipman, Jeffrey (2008) Antibiotic resistance - what's dosing got to do with it?. Critical Care Medicine, 36 8: 2433-2440. doi:10.1097/CCM.0b013e318180fe62
D. M. Roberts, J. A. Roberts, R. J. Boots, R. Mason and J. Lipman (2008) Lessons learnt in the pharmacokinetic analysis of the effect of haemoperfusion for acute overdose with sustained-release diltiazem. Anaesthesia, 63 7: 714-718. doi:10.1111/j.1365-2044.2008.05477.x
Roberts, Jason A., Paratz, Jennifer D., Paratz, Elizabeth D., Boots, Rob J. and Jeffrey Lipman (2008) Continuous infusion of time-dependent antibiotics: lung pharmacokinetics and pharmacodynamics. Clinical Pulmonary Medicine, 15 3: 167-172. doi:10.1097/CPM.0b013e3181729d3d
Jason A. Roberts, Jennifer D. Paratz and Jeffrey Lipman (2008) Continuous infusion of [beta]-lactams in the intensive care unit—Best way to hit the target?. Critical Care Medicine, 36 5: 1663-1664. doi:10.1097/CCM.0b013e3181704625
Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008) A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 3: 240-244. doi:10.1016/j.ijantimicag.2007.09.013
Roberts, Jason A. (2007) Expanding horizons - needs you to travel over them!. Journal of Pharmacy Practice and Research, 37 4: 333-333.
Roberts, Darren M. and Roberts, Jason A. (2007) Conclusions regarding the efficacy of treatments for neuroleptic malignant syndrome should be tempered given poor quality data, regardless of the analysis conducted. Critical Care, 11 3: 1-2. doi:10.1186/cc5786
Roberts, Jason A., Webb, Steven A. R. and Lipman, Jeffrey (2007) Cefepime versus ceftazidime: Considerations for empirical use in critically ill patients. International Journal of Antimicrobial Agents, 29 2: 117-128. doi:10.1016/j.ijantimicag.2006.08.031
Roberts, J. A., Boots, R., Rickard, C. M., Thomas, P., Quinn, J., Roberts, D. M., Richards, B. and Lipman, J. (2007) Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study. Journal of Antimicrobial Chemotherapy, 59 2: 285-291. doi:10.1093/jac/dkl478
Roberts, Jason A., Hsu, Millie, Allen, Karen, Willis, Jennifer and Barras, Michael (2007) Pharmacists investigating adverse penicillin responses - Pilot Study. Journal of Pharmacy Practice and Research, 37 3: 200-203.
Roberts, Jason A. and Lipman, Jeffrey (2007) Optimizing use of ß-lactum antibiotics in the critically ill. Seminars in Respiratory and Critical Care Medicine, 28 6: 579-585. doi:10.1055/s-2007-996404
Roberts, Jason A., Paratz, Jennifer, Paratz, Elizabeth, Krueger, Wolfgang A. and Lipman, Jeffrey (2007) Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role. International Journal of Antimicrobial Agents, 30 1: 11-18. doi:10.1016/j.ijantimicag.2007.02.002
Roberts, J. A. and Lipman, J. (2006) Antibacterial dosing in intensive care: Pharmacokinetics, degree of disease and pharmacodynamics of sepsis. Clinical Pharmacokinetics, 45 8: 755-773. doi:10.2165/00003088-200645080-00001
Graves, N, Weinhold, D and Roberts, JA (2005) Correcting for bias when estimating the cost of hospital-acquired infection: An analysis of lower respiratory tract infections in non-surgical patients. Health Economics, 14 7: 755-761. doi:10.1002/hec.967
Conference Papers
Adnan, Syamhanin, Li, Janice X., Lipman, Jeffrey, Wallis, Steve C. and Roberts, Jason A. (2012). Pharmacokinetics of meropenem in critically ill patients with indwelling surgical drains. In: 13th Annual Scientific Meeting Antimicrobials 2012, Brisbane Convention and Exhibition Centre, Brisbane, (). 23 - 25 February 2012.
Fraser, F., Fung, L., Diab, S., Shekar, S., Platts, D., McDonald, C., I, Panavello, M. S. and Roberts, J. (2012). ECMO: The clinician's view. In: Abstracts of the 32nd International Congress of the International Society of Blood Transfusion in joint cooperation with the 10th Congress of AMMTAC. 32nd International Congress of the International Society of Blood Transfusion in joint cooperation with the 10th Congress of AMMTAC, Cancun, Mexico, (10-10). 7-12 July 2012.
Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew, Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2010). Vancomycin Dosing in Critically Ill Patients Using Population Pharmacokinetics to Develop Personalised Dosing Regimens to Achieve Target Concentrations by Continuous Infusion. In: Critical Care Medicine. 40th Critical Care Congress, San Diego Ca, (U24-U24). Jan 15-19, 2011.
Putt, M. T., Roberts, J. A., Udy, A. A., Martin, J. H., Jarrett, P., Salmon, N. and Lipman, J. (2010). Assessment of adequacy of loading dose of phenytoin (PTN) in adult intensive care patients using population pharmacokinetics. In: ESICM 2010: Abstracts of Oral Presentations and Poster Sessions, 23rd Annual ESICM Congress. 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, (S-413-S-413). 9-13 October 2010. doi:10.1007/s00134-010-2001-7
Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. In: ESICM 2010: Abstracts of Oral Presentations and Poster Sessions, 23rd Annual ESICM Congress. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, (S200-S200). 9-13 October, 2010. doi:10.1007/s00134-010-1999-x
Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. In: ANZSN 46th Annual Scientific Meeting: Abstracts. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, (87-87). 12-15 September 2010. doi:10.1111/j.1440-1797.2010.01377_1.x
Roberts, J. A., Field, J., Visser, A., Whitbread, R., Lipman, J. and Kirkpatrick, C. (2009). Using Population Pharmacokinetics To Determine Gentamicin Dosing during Extended Daily Diafiltration in Critically Ill Patients with Acute Kidney Injury. In: Intensive Care Medicine. 22nd Annual Congress of the European Society of Intensive Care Medicine, Vienna, Austria, (265-265). 11-14 October 2009.
Greenup, L.C., Roberts, J. and Kirkpatrick, C. M. J. (2005). A comparative study of Nomogram vs Bayesian approaches to monitoring aminoglycosides. In: E.A. Davis and C.G. Sobey, Program & Abstracts: Joint Meeting of ASCEPT and APSA 2005. Joint Meeting of ASCEPT and APSA, Melbourne, (102-102). 4-7 December, 2005.
Thesis
Jason Roberts (2008). Beta-lactam antibiotic dosing in critical care units: bolus vs continuous dosing PhD Thesis, School of Medicine, The University of Queensland.