Centre of Research Excellence in Redefining
Antimicrobial Use to Reduce Resistance CRE REDUCE
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Professor Jason Roberts

CRE Director
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Researcher biography

National Health and Medical Research Council Career Development Fellow at the University of Queensland and Pharmacist Consultant at the Royal Brisbane and Women's Hospital. Professor Roberts has led multiple international pharmacokinetic studies and holds roles on multiple guideline committees.   

Featured projects Duration
Dose optimisation of anti-infective drugs in extracorporeal membrane oxygenation (ECMO) - co-sponsored by CRE ACTIONS
Exploring the impact of altered and variable antimicrobial pharmacokinetics on bacterial killing and emergence of bacterial resistance.
National Health and Medical Research Council
Therapeutic drug monitoring optimisation of antimicrobial exposures for critically ill, burns and transplant patients.
PK studies of antimicrobials in patients with VAP, CAP/ PK of antimicrobials
National Health and Medical Research Council
Antibiotic penetration into epithelial lining fluid of mechanically ventilated patients with VAP and CAP.
Continuous versus intermittent beta-lactams administration in critically ill patients with sepsis not receiving renal replacement therapy.
PK/PD of antimicrobials in other 'at risk patient groups
Exploring population variability of antimicrobial epithelial lining fluid penetration in patients with VAP.
Therapeutic drug monitoring and dose personalisation of antimicrobials in mechanically ventilated patients with Gram-negative pneumonia.
Therapeutic Drug Monitoring
National Health and Medical Research Council
SaMpling Antibiotics in Renal Replacement Therapy (SMARRT).
National Health and Medical Research Council
Development of clinical practice guidelines on antimicrobial dosing incorporating new knowledge generated by the CRE REDUCE.
BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients
National Health and Medical Research Council
Ex Vivo renal replacement therapy study to quantify the effect of differing RRT settings on antimicrobial clearance.  
Dose optimisation of anti-infectives in patients post-lung transplant
Clinical Microsampling Group
Antimicrobial pharmacokinetics in patients with cystic fibrosis, lung and bone marrow transplant.
National Health and Medical Research Council
Beta-lactam antibiotic dose optimisation in critically ill patients
Pharmacokinetics of Flucloxacillin and Lincomycin in burns patients.
National Health and Medical Research Council
Dose optimisation of antifungals and antivirals in post-lung transplant patients
Pharmacokinetics of antifungals in intensive care patients.
National Health and Medical Research Council
Using laboratory-based infection models to develop better antibiotic dosing regimens
Pharmacokinetics of antimicrobials in critically ill paediatric patients.
National Health and Medical Research Council
Anti-infective drugs
Pharmacokinetics of antimicrobials in critically ill obese patients
National Health and Medical Research Council
Sedatives and analgesics
Pharmacometric analysis of antimicrobial pharmacokinetics to propose novel and innovative dosing regimens.
National Health and Medical Research Council

Publications

Book Chapters (24)
Journal Articles (510)
Conference Papers (28)
Thesis (1)

Book Chapters

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical pharmacy considerations in ICU. Encyclopedia of pharmacy practice and clinical pharmacy. (pp. 849-865) edited by Zaheer-Ud-Din Babar. Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8
Sokn, Erick, Calabrese, Sam, Scheckelhoff, Douglas, Thomas, Dixon and Roberts, Jason A. (2018). Advanced clinical pharmacy practitioner. Clinical Pharmacy Education, Practice and Research: Clinical Pharmacy, Drug Information, Pharmacovigilance, Pharmacoeconomics and Clinical Research. (pp. 465-472) London, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-814276-9.00033-7
Sime, Fekade B. and Roberts, Jason A. (2018). Appropriate antimicrobial therapy in critically ill patients. Abdominal Sepsis: a multidisciplinary approach. (pp. 319-342) edited by Massimo Sartelli, Matteo Bassetti and Ignacio Martin-Loeches. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-59704-1_21
Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2018). Preface. Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically Ill. (pp. v-vii) edited by Andrew A. Udy, Jason A. Roberts and Jeffrey Lipman. Singapore, Singapore: Springer Singapore.
Sime, Fekade B. and Roberts, Jason A. (2018). Antibiotic pharmacodynamics. Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill. (pp. 17-29) edited by Andrew Udy, Jason A. Roberts and Jeffrey Lipman. Singapore, Singapore: Springer Nature. doi: 10.1007/978-981-10-5336-8_2
Geddes, Alasdair M., Gould, Ian M. and Roberts, Jason A. (2017). Phenoxypenicillins. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 92-99) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Geddes, Alasdair M., Gould, Ian M., Roberts, Jason A., Lindsay Grayson, M. and Cosgrove, Sara E. (2017). Ampicillin and amoxicillin. Kucers’ the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 100-135) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Denny, Kerina J., Lipman, Jeffrey and Roberts, Jason A. (2017). Cephalothin and cefazolin. Kucers the use of antibiotics: A clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 347-360) Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Geddes, Alasdair M., Gould, Ian M., Roberts, Jason A., Trubiano, Jason A. and Lindsay Grayson, M. (2017). Benzylpenicillin (penicillin G). Kucers’ the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs. (pp. 23-91) edited by M. Lindsay Grayson, Sara E. Cosgrove, Suzanne Crowe, William Hope, James S. McCarthy, John Mills, Johan W. Mouton and David L. Paterson. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781315152110
Sinnollareddy, Mahipal G., Cotta, Menino O. and Roberts, Jason A. (2017). Pharmacokinetic and pharmacodynamic tools to increase efficacy. Developments in emerging and existing infectious diseases: Antimicrobial stewardship. (pp. 85-98) edited by Celine Pulcini, Önder Ergönül, Füsun Can and Bojana Beović. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810477-4.00007-6
Abdul-Aziz, M. H., Shekar, Kiran and Roberts, Jason A. (2017). Antibiotic dosing during extracorporeal membrane oxygenation. Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill. (pp. 151-171) Gateway East, Singapore: Springer Singapore. doi: 10.1007/978-981-10-5336-8_8
Sinnollareddy, Mahipal G. and Roberts, Jason A. (2016). Pharmacodynamic considerations in critically ill patients. Antibiotic pharmacodynamics. (pp. 537-560) edited by John C. Rotschafer, David R. Andes and Keith A. Rodvold. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-3323-5_21
Osbert Cotta, Menino and Roberts, Jason (2016). Pharmacokinetic and pharmacodynamic principles of antimicrobials. Antimicrobial stewardship. (pp. 71-78) edited by Matthew Laundy, Mark Gilchrist and Laura Whitney. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780198758792.003.0009
Jamal, Janattul-Ain and Roberts, Jason A. (2016). Polyene antifungals. Drug Dosing in Obesity: Volume I: Antimicrobials. (pp. 109-115) edited by Syed Tabish R. Zaidi and Jason A. Roberts. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-44034-7_10
Jamal, Janattul-Ain and Roberts, Jason A. (2016). Aminoglycoside dosing in obesity. Drug Dosing in Obesity: Volume I: Antimicrobials. (pp. 39-44) edited by Syed Tabish R. Zaidi and Jason A. Roberts. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-44034-7_4
Thorley, Bruce R. and Roberts, Jason A. (2016). Isolation and characterization of poliovirus in cell culture systems. Poliovirus: methods and protocols. (pp. 29-53) edited by Javier Martin. New York, United States: Humana Press. doi: 10.1007/978-1-4939-3292-4_4
Ulldemolins, Marta and Roberts, Jason A. (2012). How do I adjust antimicrobial daily dosage in patients with MODS? a pharmacist’s contribution. Sepsis management: PIRO and MODS. (pp. 199-216) edited by Jordi Rello, Jeffrey Lipman and Thiago Lisboa. Berlin, Germany: Springer.
Ulldemolins, M., Roberts, J. A. and Rello, J. (2010). Drug distribution: is it a more important determinant of drug dosing than clearance?. Intensive care medicine: annual update 2010. (pp. 507-516) Brussels, Belgium: Springer. doi: 10.1007/978-1-4419-5562-3_47
Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. Yearbook of Intensive Care and Emergency Medicine 2010. (pp. 495-506) edited by J.-L. Vincent. Brussels, Belgium: Springer Verlag. doi: 10.1007/978-3-642-10286-8
Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. Critical Care Update 2009. (pp. 128-142) edited by Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas. Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.
Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. Patient safety and quality of care in intensive care medicine. (pp. 291-304) edited by Jean-Daniel Chiche and Leanne M. Aitken. Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.
Udy, Andrew, Roberts, Jason, Boots, Robert and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic Shock. Sepsis: New Strategies for Management. (pp. 97-136) Berlin, Heidelberg: Springer Berlin Heidelberg. doi: 10.1007/978-3-540-79001-3_8
Udy, Andrew, Roberts, Jason A., Boots, Robert J. and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock. Sepsis: New strategies for management. (pp. 97-102) edited by Jordi Rello and Marcos I. Restrepo. London: Springer-Verlag. doi: 10.1007/978-3-540-79001-3
Roberts, J. A. and Lipman, J. (2007). Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock. Infectious diseases in critical care. (pp. 122-146) edited by Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez. Berlin, Germany; New York, U.S.A.: Springer. doi: 10.1007/978-3-540-34406-3_12

Journal Articles

Roger, Claire, Louart, Benjamin, Elotmani, Loubna, Barton, Greg, Escobar, Leslie, Koulenti, Despoina, Lipman, Jeffrey, Leone, Marc, Muller, Laurent, Boutin, Caroline, Amour, Julien, Banakh, Iouri, Cousson, Joel, Bourenne, Jeremy, Constantin, Jean-Michel, Albanese, Jacques, Roberts, Jason A., Lefrant, Jean-Yves, Darchy, Bruno, Sigismond, Lasocki, Debbat, Karim, Moschietto, Sébastien, Capellier, Gilles, Biais, Matthieu, Brunin, Guillaume, Huet, Olivier, Hausermann, Marie-Hélène, Just, Bernard, Constantin, Jean-Michel ... Felton, Timothy (2021). An international survey on aminoglycoside practices in critically ill patients: the AMINO III study. Annals of Intensive Care, 11 (1) 49, 49. doi: 10.1186/s13613-021-00834-4
Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11, 667680. doi: 10.3389/fcimb.2021.667680
Chiriac, Ute, Frey, Otto R., Roehr, Anka C., Koeberer, Andreas, Gronau, Patrick, Fuchs, Thomas, Roberts, Jason A. and Brinkmann, Alexander (2021). Personalized ß-lactam dosing in patients with coronavirus disease 2019 (COVID-19) and pneumonia: A retrospective analysis on pharmacokinetics and pharmacokinetic target attainment. Medicine, 100 (22) e26253, 1-7. doi: 10.1097/MD.0000000000026253
Chiriac, Ute, Richter, Daniel C., Frey, Otto R., Röhr, Anka C., Helbig, Sophia, Preisenberger, Judit, Hagel, Stefan, Roberts, Jason A., Weigand, Markus A. and Brinkmann, Alexander (2021). Personalized piperacillin dosing for the critically ill: a retrospective analysis of clinical experience with dosing software and therapeutic drug monitoring to optimize antimicrobial dosing. Antibiotics, 10 (6) 667, 667. doi: 10.3390/antibiotics10060667
Cairns, Kelly A., Avent, Minyon, Buono, Evette, Cheah, Ron, Devchand, Misha, Khumra, Sharmila, Rawlins, Matthew, Roberts, Jason A., Xenos, Kristin and Munro, Courtney (2021). Standard of practice in infectious diseases for pharmacy services. Journal of Pharmacy Practice and Research, 51 (3), 247-264. doi: 10.1002/jppr.1744
Selby, Philip Roland, Shakib, Sepehr, Peake, Sandra L., Warner, Morgyn S., Yeung, David, Hahn, Uwe and Roberts, Jason A. (2021). A systematic review of the clinical pharmacokinetics, pharmacodynamics and toxicodynamics of ganciclovir/valganciclovir in allogeneic haematopoietic stem cell transplant patients. Clinical Pharmacokinetics, 60 (6), 727-739. doi: 10.1007/s40262-020-00982-z
Zhu, Yinggang, Monsel, Antoine, Roberts, Jason A., Pontikis, Konstantinos, Mimoz, Olivier, Rello, Jordi, Qu, Jieming, Rouby, Jean-Jacques and on behalf of the European Investigator Network for Nebulized Antibiotics in Ventilator-Associated Pneumonia (ENAVAP) (2021). Nebulized colistin in ventilator-associated pneumonia and tracheobronchitis: historical background, pharmacokinetics and perspectives. Microorganisms, 9 (6) 1154, 1-25. doi: 10.3390/microorganisms9061154
Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7
Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 1-5. doi: 10.1038/s41390-021-01586-4
Heffernan, Aaron, Alawie, Jowana, Wallis, Steven C., Naicker, Saiyuri, Adiraju, Santosh, Roberts, Jason A. and Sime, Fekade Bruck (2021). Pharmacodynamic evaluation of a single dose versus a 24-hour course of multiple doses of cefazolin for surgical prophylaxis. Antibiotics, 10 (5) 602, 602. doi: 10.3390/antibiotics10050602
Burke, Andrew, Smith, Daniel, Coulter, Chris, Bell, Scott C., Thomson, Rachel and Roberts, Jason A. (2021). Clinical pharmacokinetic and pharmacodynamic considerations in the drug treatment of non-tuberculous mycobacteria in cystic fibrosis. Clinical Pharmacokinetics. doi: 10.1007/s40262-021-01010-4
Islam, Kamrul, Heffernan, Aaron J., Naicker, Saiyuri, Henderson, Andrew, Chowdhury, Mohammed Abdul Hassan, Roberts, Jason A. and Sime, Fekade B. (2021). Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing in South Asia. Future Microbiology, 16 (7) fmb-2020-0193, 521-535. doi: 10.2217/fmb-2020-0193
Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042
Gijsen, Matthias, Annaert, Pieter, Shekar, Kiran, Roberts, Jason A., Wauters, Joost and Spriet, Isabel (2021). Ceftriaxone exposure in patients undergoing extracorporeal membrane oxygenation. International Journal of Antimicrobial Agents, 57 (5) 106326, 106326. doi: 10.1016/j.ijantimicag.2021.106326
Li, Jian and Roberts, Jason (2021). Antibiotic Pharmacokinetics/Pharmacodynamics: Where are we heading?. International Journal of Antimicrobial Agents, 58 (2) 106369, 106369. doi: 10.1016/j.ijantimicag.2021.106369
Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Zowawi, Hosam M., Roberts, Jason A. and Sime, Fekade B. (2021). Semi-mechanistic PK/PD modelling of meropenem and sulbactam combination against carbapenem-resistant strains of Acinetobacter baumannii. European Journal of Clinical Microbiology and Infectious Diseases. doi: 10.1007/s10096-021-04252-z
Mohd Sazlly Lim, S., Heffernan, A.J., Roberts, J.A. and Sime, F.B. (2021). Semi-mechanistic PK/PD modelling of fosfomycin and sulbactam combination against carbapenem-resistant Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy, 65 (5) e02472-20. doi: 10.1128/aac.02472-20
Garbez, Nicolas, Mbatchi, Litaty, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Antimicrobial Agents and Chemotherapy, 65 (7) e02307-20, e0230720. doi: 10.1128/aac.02307-20
Heffernan, Aaron J., Sime, Fekade B., Lim, Sazlyna Mohd Sazlly, Naicker, Saiyuri, Andrews, Katherine T., Ellwood, David, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2021). Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa. Drugs in R&D, 21 (2), 203-215. doi: 10.1007/s40268-021-00344-5
Johnston, Karlee, Ankravs, Melissa J., Badman, Belinda, Choo, Chui Lynn, Cree, Michele, Fyfe, Rachel, Roberts, Jason A., Xu, Jessica and Munro, Courtney (2021). Standard of ​practice in intensive care for pharmacy services. Journal of Pharmacy Practice and Research, 51 (2), 165-183. doi: 10.1002/jppr.1718
Agyeman, Akosua A., Rogers, Kate E., Tait, Jessica R., Bergen, Phillip J., Kirkpatrick, Carl M., Wallis, Steven C., Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2021). Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance. Clinical Pharmacology and Therapeutics, 109 (4), 1104-1115. doi: 10.1002/cpt.2191
Barreto, Erin F., Rule, Andrew D., Alshaer, Mohammad H., Roberts, Jason A., Abdul Aziz, Mohd Hafiz, Scheetz, Marc H., Mara, Kristin C., Jannetto, Paul J., Gajic, Ognjen, O'Horo, John C and Boehmer, Kasey R (2021). Provider perspectives on beta-lactam therapeutic drug monitoring programs in the critically ill: a protocol for a multicenter mixed-methods study. Implementation science communications, 2 (1) 34, 34. doi: 10.1186/s43058-021-00134-9
Raza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280
Heffernan, Aaron James, Sime, Fekade Bruck, Naicker, Saiyuri, Andrews, Katherine, Ellwood, David, Guerra-Valero, Yarmarly, Wallis, Steven, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason Alexander (2021). Pharmacodynamics of once- versus twice-daily dosing of nebulized amikacin in an in vitro Hollow-Fiber Infection Model against 3 clinical isolates of Pseudomonas aeruginosa. Diagnostic microbiology and infectious disease, 100 (2) 115329, 115329. doi: 10.1016/j.diagmicrobio.2021.115329
Dhanani, Jayesh A., Goodman, Steven, Ahern, Benjamin, Cohen, Jeremy, Fraser, John F., Barnett, Adrian, Diab, Sara, Bhatt, Manoj and Roberts, Jason A. (2021). Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study. International Journal of Antimicrobial Agents, 57 (2) 106232, 106232. doi: 10.1016/j.ijantimicag.2020.106232
Kato, Hideo, Parker, Suzanne L., Roberts, Jason A., Hagihara, Mao, Asai, Nobuhiro, Yamagishi, Yuka, Paterson, David L. and Mikamo, Hiroshige (2021). Population pharmacokinetics analysis of amikacin initial dosing regimen in elderly patients. Antibiotics, 10 (2) 100, 1-13. doi: 10.3390/antibiotics10020100
Sime, Fekade Bruck, Roberts, Jason A., Jeffree, Rosalind L., Pandey, Saurabh, Adiraju, Santosh, Livermore, Amelia, Butler, Jenie, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Cotta, Menino Osbert (2021). Population pharmacokinetics of levetiracetam in patients with traumatic brain injury and subarachnoid hemorrhage exhibiting augmented renal clearance. Clinical Pharmacokinetics, 60 (5), 655-664. doi: 10.1007/s40262-020-00979-8
Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284
Abbott, Iain J., Roberts, Jason A., Meletiadis, Joseph and Peleg, Anton Y. (2021). Antimicrobial pharmacokinetics and preclinical in vitro models to support optimized treatment approaches for uncomplicated lower urinary tract infections. Expert Review of Anti-infective Therapy, 19 (3), 271-295. doi: 10.1080/14787210.2020.1813567
Ho, Su Ann, Slavin, Monica, Roberts, Jason A. and Yong, Michelle (2020). Optimization of Ganciclovir use in allogeneic hematopoietic cell transplant recipients – the role of therapeutic drug monitoring. Expert Review of Anti-infective Therapy, 19 (6), 1-12. doi: 10.1080/14787210.2021.1851193
Sime, Fekade B, Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain. Antimicrobial Agents and Chemotherapy, 65 (1) e01698-20, 1-11. doi: 10.1128/aac.01698-20
Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey, Wong, Wai Tat, Joynt, Gavin M. and Cotta, Menino Osbert (2020). A systematic review of studies reporting antibiotic pharmacokinetic data in the cerebrospinal fluid of critically Ill patients with uninflamed meninges. Antimicrobial Agents and Chemotherapy, 65 (1) e01998-20, 1-19. doi: 10.1128/aac.01998-20
Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196
Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004
Liu, Jiajun, Rhodes, Nathaniel J., Roberts, Jason A., Pais, Gwendolyn M., Turner, Ben, Kiel, Patrick J. and Scheetz, Marc H. (2020). β-lactam dosing strategies: think before you push. International Journal of Antimicrobial Agents, 56 (5) 106151, 106151. doi: 10.1016/j.ijantimicag.2020.106151
Perin, Nicolas, Roger, Claire, Marin, Grégory, Molinari, Nicolas, Evrard, Alexandre, Lavigne, Jean-Philippe, Barbar, Saber, Claret, Pierre Géraud, Boutin, Caroline, Muller, Laurent, Lipman, Jeffrey, Lefrant, Jean-Yves, Jaber, Samir and Roberts, Jason A. (2020). Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit. Antibiotics, 9 (11) 793, 1-16. doi: 10.3390/antibiotics9110793
Ezure, Yukiko, Rico, Veronica, Paterson, David L., Hall, Lisa, Harris, Patrick N. A., Soriano, Alex, Roberts, Jason A., Bassetti, Matteo, Roberts, Matthew J., Righi, Elda and Wright, Hugh (2020). Efficacy and safety of carbapenems versus new antibiotics for treatment of adult patients with complicated urinary tract infections: a systematic review and meta-analysis. Open Forum Infectious Diseases. doi: 10.1093/ofid/ofaa480
Abdul-Aziz, Mohd H., Portunato, Federica and Roberts, Jason A. (2020). Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base. Current Opinion in Infectious Diseases, Publish Ahead of Print (6), 501-510. doi: 10.1097/qco.0000000000000681
Imani, Sahand, Alffenaar, Jan-Willem, Cotta, Menino O., Daveson, Kathryn, van Hal, Sebastiaan, Lau, Cindy, Marriott, Debbie, Penm, Jonathan, Roberts, Jason A., Tabah, Alexis, Trethewy, Nicholas, Williams, Paul and Sandaradura, Indy (2020). Therapeutic drug monitoring of commonly used anti-infective agents: A nationwide cross-sectional survey of Australian hospital practices. International Journal of Antimicrobial Agents, 56 (6) 106180, 106180. doi: 10.1016/j.ijantimicag.2020.106180
Heffernan, Aaron J., Curran, Rebecca A., Denny, Kerina J., Sime, Fekade B., Stanford, Claire L., McWhinney, Brett, Ungerer, Jacobus, Roberts, Jason A. and Lipman, Jeffrey (2020). Ceftriaxone dosing in patients admitted from the emergency department with sepsis. European Journal of Clinical Pharmacology, 77 (2), 207-214. doi: 10.1007/s00228-020-03001-z
Parker, Suzanne L., Abdul-Aziz, Mohd Hafiz and Roberts, Jason A. (2020). The role of antibiotic pharmacokinetic studies performed post-licensing. International Journal of Antimicrobial Agents, 56 (6) 106165, 106165. doi: 10.1016/j.ijantimicag.2020.106165
Mohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Roberts, Jason A. and Sime, Fekade B. (2020). Pharmacodynamic Analysis of Meropenem and Fosfomycin Combination Against Carbapenem-Resistant in Patients with Normal Renal Clearance: Can It Be a Treatment Option?. Microbial drug resistance (Larchmont, N.Y.), 27 (4) mdr.2020.0197, 546-552. doi: 10.1089/mdr.2020.0197
Economou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058
Coombes, Ian D., Dooley, Michael J., Townsend, Shane, Carmichael, Sinead, Poole, Susan G., Karamujic, Nermin, Richards, Brent, Ziegenfuss, Marc, Ankravs, Melissa J., Uren, Hailie, Roberts, Jason A. and Holley, Anthony (2020). Physician drug prescribing preferences and availability for ventilation of patients with COVID-19. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 22 (3), 271-274.
Marella, Prashanti, Roberts, Jason, Hay, Karen and Shekar, Kiran (2020). Effectiveness of therapeutic drug monitoring guided vancomycin dosing in adult patients receiving extra corporeal membrane oxygenation. Antimicrobial Agents and Chemotherapy, 64 (9) e01179-20. doi: 10.1128/aac.01179-20
Cotta, Menino Osbert, Abdul-Aziz, Mohd Hafiz, Frey, Otto R., Sime, Fekade Bruck, Roberts, Jason A. and Roehr, Anka C. (2020). What are the predictors for achieving therapeutic levetiracetam serum concentrations in adult neurological patients?. Therapeutic Drug Monitoring, 42 (4), 626-630. doi: 10.1097/ftd.0000000000000731
Märtson, A. G., Sturkenboom, M. G. G., Stojanova, J., Cattaneo, D., Hope, W., Marriott, D., Patanwala, A. E., Peloquin, C. A., Wicha, S. G., van der Werf, T. S., Tängdén, T., Roberts, J. A., Neely, M. N. and Alffenaar, J. W. C. (2020). How to design a study to evaluate therapeutic drug monitoring in infectious diseases?. Clinical Microbiology and Infection, 26 (8), 1008-1016. doi: 10.1016/j.cmi.2020.03.008
Zeitlinger, Markus, Koch, Birgit C. P., Bruggemann, Roger, De Cock, Pieter, Felton, Timothy, Hites, Maya, Le, Jennifer, Luque, Sonia, MacGowan, Alasdair P., Marriott, Deborah J. E., Muller, Anouk E., Nadrah, Kristina, Paterson, David L., Standing, Joseph F., Telles, João P., Wölfl-Duchek, Michael, Thy, Michael and Roberts, Jason A. (2020). Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents. Clinical Pharmacokinetics, 59 (10), 1195-1216. doi: 10.1007/s40262-020-00924-9
Dhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6
Denholm, Justin T., Davis, Joshua, Paterson, David, Roberts, Jason, Morpeth, Susan, Snelling, Thomas, Zentner, Dominica, Rees, Megan, O'Sullivan, Matthew, Price, David, Bowen, Asha, Tong, Steven Y. C., Davis, Joshua, Denholm, Justin, Tong, Steven, ASCOT Investigator Group, Rees, Megan, Paterson, David, Price, David, Morpeth, Susan, O'Sullivan, Matthew, Roberts, Jason, Snelling, Thomas, Anderson, Sue, McQuilton, Zoe, Venkatesh, Bala, Hammond, Naomi, Jha, Vivekanend, Burston, Victoria John ... Slow, Sandy (2020). The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial. Trials, 21 (1) 646. doi: 10.1186/s13063-020-04576-9
Heffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20
Cusumano, Jaclyn A., Klinker, Kenneth P., Huttner, Angela, Luther, Megan K., Roberts, Jason A. and LaPlante, Kerry L. (2020). Towards precision medicine: therapeutic drug monitoring-guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity. American Journal of Health-System Pharmacy, 77 (14), 1104-1112. doi: 10.1093/ajhp/zxaa128
Scuderi, Carla E., Parker, Suzanne L., Jacks, Margaret, John, George, McWhinney, Brett, Ungerer, Jacobus, Mallett, Andrew, Roberts, Jason A., Healy, Helen and Staatz, Christine E. (2020). Kidney transplant recipient’s perceptions of blood testing through microsampling and venepuncture. Bioanalysis, 12 (13) bio-2020-0057, 873-881. doi: 10.4155/bio-2020-0057
Mohd Sazlly Lim, S., Naicker, S., Ayfan, A. K., Zowawi, H., Roberts, J. A. and Sime, F. B. (2020). Non-polymyxin based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections. International Journal of Antimicrobial Agents, 56 (4) 106115, 106115. doi: 10.1016/j.ijantimicag.2020.106115
Dhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7). doi: 10.1128/aac.02584-19
Chai, Ming G., Cotta, Menino O., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). What are the current approaches to optimising antimicrobial dosing in the intensive care unit?. Pharmaceutics, 12 (7) 638, 1-22. doi: 10.3390/pharmaceutics12070638
Sumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211
Bilal, Hajira, Bergen, Phillip J., Tait, Jessica R., Wallis, Steven C., Peleg, Anton Y., Roberts, Jason A., Oliver, Antonio, Nation, Roger L. and Landersdorfer, Cornelia B. (2020). Clinically relevant epithelial lining fluid concentrations of meropenem with ciprofloxacin provide synergistic killing and resistance suppression of hypermutable Pseudomonas aeruginosa in a dynamic biofilm model. Antimicrobial Agents and Chemotherapy, 64 (7) e00469-20. doi: 10.1128/aac.00469-20
Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Wallis, Steven C., Pandey, Saurabh, Roberts, Jason A., Lipman, Jeffrey, De Cock, Pieter and Devreese, Mathias (2020). Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers. Frontiers in Pharmacology, 11 883, 883. doi: 10.3389/fphar.2020.00883
De Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5
Coombes, Ian, Markwell, Alexandra, Kubler, Paul, Redmond, Andrew M., McGurk, Gordon and Roberts, Jason A. (2020). Principles of ethical prescribing for self and others: hydroxychloroquine in the COVID-19 pandemic. Australian Prescriber, 43 (3), 76-77. doi: 10.18773/austprescr.2020.030
Hernández-Mitre, María Patricia, Medellín-Garibay, Susanna Edith, Rodríguez-Leyva, Ildefonso, Rodríguez-Pinal, Cristian Jazmín, Zarazúa, Sergio, Jung-Cook, Helgi Helene, Roberts, Jason A., Romano-Moreno, Silvia and Milán-Segovia, Rosa del Carmen (2020). Population pharmacokinetics and dosing recommendations of levetiracetam in adult and elderly patients with epilepsy. Journal of Pharmaceutical Sciences, 109 (6), 2070-2078. doi: 10.1016/j.xphs.2020.02.018
Eisen, Damon P., McEwen, Peter, Hansen, Regina, Pandey, Saurabh, Wallis, Steven C. and Roberts, Jason A. (2020). Low levels of salicylic acid and salicyluric acid are present in synovial fluid of patients taking aspirin at the time of knee arthroplasty surgery. Clinical and Experimental Pharmacology and Physiology, 47 (9) 1440-1681.13333, 1635-1637. doi: 10.1111/1440-1681.13333
Jager, Nynke G. L., van Hest, Reinier M., Xie, Jiao, Wong, Gloria, Ulldemolins, Marta, Brüggemann, Roger J. M., Lipman, Jeffrey and Roberts, Jason A. (2020). Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations. Journal of Antimicrobial Chemotherapy, 75 (9), 2641-2649. doi: 10.1093/jac/dkaa187
Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Wicha, Sebastian G. (2020). An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapy. Pharmaceutical Research, 37 (6) 96, 96. doi: 10.1007/s11095-020-02832-w
Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report. Pharmacotherapy, 40 (7) phar.2413, 713-717. doi: 10.1002/phar.2413
Abdul-Aziz, Mohd H., Alffenaar, Jan-Willem C., Bassetti, Matteo, Bracht, Hendrik, Dimopoulos, George, Marriott, Deborah, Neely, Michael N., Paiva, Jose-Artur, Pea, Federico, Sjovall, Fredrik, Timsit, Jean F., Udy, Andrew A., Wicha, Sebastian G., Zeitlinger, Markus, De Waele, Jan J., Roberts, Jason A., the Infection Section of European Society of Intensive Care Medicine (ESICM), Pharmacokinetic/pharmacodynamic and Critically Ill Patient Study Groups of European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Group of International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) and Infections in the ICU and Sepsis Working Group of International Society of Antimicrobial Chemotherapy (ISAC) (2020). Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#. Intensive Care Medicine, 46 (6), 1127-1153. doi: 10.1007/s00134-020-06050-1
Abbott, Iain J., van Gorp, Elke, van der Meijden, Aart, Wijma, Rixt A., Meletiadis, Joseph, Roberts, Jason A., Mouton, Johan W. and Peleg, Anton Y. (2020). Oral fosfomycin treatment for enterococcal urinary tract infections in a dynamic in vitro model. Antimicrobial Agents and Chemotherapy, 64 (6) e00342-20. doi: 10.1128/aac.00342-20
Ates, H. Ceren, Roberts, Jason A., Lipman, Jeffrey, Cass, Anthony E.G., Urban, Gerald A. and Dincer, Can (2020). On-site therapeutic drug monitoring. Trends in Biotechnology, 38 (11), 1262-1277. doi: 10.1016/j.tibtech.2020.03.001
Dhaese, Sofie A. M., Thooft, Alexander D. J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2020). Corrigendum to “Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study” [Journal of Critical Care 52 (2019) 75–79]. Journal of Critical Care, 56, 325-325. doi: 10.1016/j.jcrc.2019.09.020
Eley, Victoria A., Christensen, Rebecca, Ryan, Rochelle, Jackson, Dwane, Parker, Suzanne L., Smith, Matthew, van Zundert, Andre A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). Prophylactic cefazolin dosing in women with body mass index >35 kg·m−2 undergoing cesarean delivery : a pharmacokinetic study of plasma and interstitial fluid. Anesthesia and Analgesia, 131 (1), 1-207. doi: 10.1213/ane.0000000000004766
Rouby, J. J., Sole-Lleonart, C., Rello, J., Monsel, Antoine, Constantin, Jean-Michel, Bouglé, Adrien, Blot, Stijn, Poulakou, Garyphalia, Pontikis, Konstantinos, Kyriakoudi, Anna, Koutsoukou, Antonia, Dimopoulos, George, Routsi, Christina, Arvaniti, Kostoula, Pereira, Jose Manuel, Felton, Timothy, Dhanani, Jayesh, Roberts, Jason, Bassetti, Matteo, Welte, Tobias, Dugernier, Jonathan, Laterre, Pierre-François, Ehrmann, Stephan, Boisson, Matthieu, Mimoz, Olivier, Leone, Marc, Palmer, Lucy B., Pugin, Jérôme, Qu, Jie-ming ... Liao, Xuelian (2020). Correction to: Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin (Intensive Care Medicine, (2020), 46, 4, (766-770), 10.1007/s00134-019-05890-w). Intensive Care Medicine, 46 (4), 766-770. doi: 10.1007/s00134-020-05986-8
Roberts, Jason A., Joynt, Gavin M., Lee, Anna, Choi, Gordon, Bellomo, Rinaldo, Kanji, Salmaan, Mudaliar, M Yugan, Peake, Sandra L., Stephens, Dianne, Taccone, Fabio Silvio, Ulldemolins, Marta, Valkonen, Miia Maaria, Agbeve, Julius, Baptista, João P., Bekos, Vasileios, Boidin, Clement, Brinkmann, Alexander, Buizen, Luke, Castro, Pedro, Cole, C. Louise, Creteur, Jacques, De Waele, Jan J., Deans, Renae, Eastwood, Glenn M., Escobar, Leslie, Gomersall, Charles, Gresham, Rebecca, Jamal, Janattul Ain, Kluge, Stefan ... Young, Helen (2020). The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study. Clinical Infectious Diseases, 72 (8), 1369-1378. doi: 10.1093/cid/ciaa224
Liu, Jiajun, Neely, Michael, Lipman, Jeffrey, Sime, Fekade, Roberts, Jason A., Kiel, Patrick J., Avedissian, Sean N., Rhodes, Nathaniel J. and Scheetz, Marc H. (2020). Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime. Clinical Pharmacokinetics, 59 (8), 1027-1036. doi: 10.1007/s40262-020-00873-3
Lonsdale, Dagan Osborne, Lipman, Jeffrey, Livermore, Amelia, McWhinney, Brett, Ungerer, Jacobus P.J. and Roberts, Jason A. (2020). Amoxicillin-clavulanate dosing in the intensive care unit: the additive effect of renal replacement therapy in a patient with normal kidney function. Chemotherapy, 64 (4), 1-4. doi: 10.1159/000505057
Lai, Tony, Alffenaar, Jan-Willem, Kesson, Alison, Bandodkar, Sushil and Roberts, Jason A. (2020). Evaluation of target attainment of oral posaconazole suspension in immunocompromised children. Journal of Antimicrobial Chemotherapy, 75 (3), 726-729. doi: 10.1093/jac/dkz481
Heffernan, Aaron James, Sime, Fekade Bruck, Sun, Jing, Lipman, Jeffrey, Kumar, Anand, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason (2020). β-lactam antibiotic versus combined β-lactam antibiotic and single-daily dosing regimens of aminoglycosides for the treatment of serious infections: a meta-analysis. International Journal of Antimicrobial Agents, 55 (3) 105839, 105839. doi: 10.1016/j.ijantimicag.2019.10.020
Cogen, Jonathan D., Kahl, Barbara C., Maples, Holly, McColley, Susanna A., Roberts, Jason A., Winthrop, Kevin L., Morris, Andrew M., Holmes, Alison, Flume, Patrick A., VanDevanter, Donald R., Waters, Valerie, Muhlebach, Marianne S., Elborn, J. Stuart, Saiman, Lisa and Bell, Scott C. (2020). Finding the relevance of antimicrobial stewardship for cystic fibrosis. Journal of Cystic Fibrosis, 19 (4), 511-520. doi: 10.1016/j.jcf.2020.02.012
Wong, Gloria, Taccone, Fabio, Villois, Paola, Scheetz, Marc H., Rhodes, Nathaniel J., Briscoe, Scott, McWhinney, Brett, Nunez-Nunez, Maria, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2020). β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill. Journal of Antimicrobial Chemotherapy, 75 (2), 429-433. doi: 10.1093/jac/dkz437
Crass, Ryan L., Williams, Paul and Roberts, Jason A. (2020). The challenge of quantifying and managing pharmacokinetic variability of beta-lactams in the critically ill. Anaesthesia Critical Care and Pain Medicine, 39 (1), 27-29. doi: 10.1016/j.accpm.2019.12.008
Abbott, Iain J., van Gorp, Elke, Wijma, Rixt A., Meletiadis, Joseph, Roberts, Jason A., Mouton, Johan W. and Peleg, Anton Y. (2020). Oral fosfomycin efficacy with variable urinary exposures following single and multiple doses against Enterobacterales: the importance of heteroresistance on growth outcome. Antimicrobial Agents and Chemotherapy, 64 (3) e01982-19. doi: 10.1128/aac.01982-19
Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19
Alves, Geisa Cristina da Silva, Silva, Samuel Dutra da, Chequer, Farah Maria Drumond, Castro, Whocely Victor de, Baldoni, André Oliveira, Farkas, Andras, Daróczi, Gergely, Roberts, Jason Alexander and Sanches, Cristina (2020). Software for dose adjustment of antimicrobials. Implications for plasma concentrations and pratical limitations. Einstein, 18, 1-2. doi: 10.31744/einstein_journal/2020ce5858
Silva, Samuel Dutra da, Alves, Geisa Cristina da Silva, Chequer, Farah Maria Drumond, Farkas, Andras, Daróczi, Gergely, Roberts, Jason A. and Sanches, Cristina (2020). Linguistic and cultural adaptation to the Portuguese language of antimicrobial dose adjustment software. Einstein (São Paulo), 18, 1-8. doi: 10.31744/einstein_journal/2020ao5023
Xie, Jiao, Roberts, Jason A., Lipman, Jeffrey, Cai, Yan, Wang, Haitao, Zhao, Nuannuan, Xu, Xiaona, Yang, Shan, Li, Youjia and Zhang, Kanghuai (2020). Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations. International Journal of Antimicrobial Agents, 55 (6) 105943, 105943. doi: 10.1016/j.ijantimicag.2020.105943
Donnellan, Sine, Wright, Daniel F. B., Roberts, Jason A., Duffull, Stephen B., Schollum, John B. W., Putt, Tracey L., Wallis, Steven C. and Walker, Robert J. (2020). The pharmacokinetics of meropenem and piperacillin-tazobactam during sustained low efficiency haemodiafiltration (SLED-HDF). European Journal of Clinical Pharmacology, 76 (2), 239-247. doi: 10.1007/s00228-019-02792-0
Yadav, Rajbharan, Bergen, Phillip J., Rogers, Kate E., Kirkpatrick, Carl M. J., Wallis, Steven C., Huang, Yuling, Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2020). Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients. Antimicrobial Agents and Chemotherapy, 64 (1) e01679-19. doi: 10.1128/aac.01679-19
Raby, Edward, Naicker, Saiyuri, Sime, Fekade Bruck, Manning, Laurens, Wallis, Steven C., Pandey, Saurabh and Roberts, Jason A. (2019). Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study. European Journal of Hospital Pharmacy, 27 (e1) e19002093, e84-e86. doi: 10.1136/ejhpharm-2019-002093
Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019). Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 (6), 741-749. doi: 10.1016/j.ijantimicag.2019.08.024
Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019). Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 41 (6), 703-713. doi: 10.1097/ftd.0000000000000658
Breilh, Dominique, Honore, Patrick M., De Bels, David, Roberts, Jason A., Gordien, Jean Baptiste, Fleureau, Catherine, Dewitte, Antoine, Coquin, Julien, Roze, Hadrien, Perez, Paul, Attou, Rachid, Redant, Sebastien, Kugener, Luc, Saux, Marie-Claude, Spapen, Herbert D., Ouattare, Alexandre and Joannes-Boyau, Olivier (2019). Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial. Journal of Translational Internal Medicine, 7 (4), 155-169. doi: 10.2478/jtim-2019-0031
Luque, Sonia, Muñoz-Bermudez, Rosana, Echeverría-Esnal, Daniel, Sorli, Luisa, Campillo, Nuria, Martínez-Casanova, Javier, González-Colominas, Elena, Álvarez-Lerma, Francisco, Horcajada, Juan Pablo, Grau, Santiago and Roberts, Jason A. (2019). Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity. Therapeutic Drug Monitoring, 41 (6), 732-739. doi: 10.1097/FTD.0000000000000665
Leone, Marc, Roberts, Jason A., Bassetti, Matteo, Bouglé, Adrien, Lavigne, Jean-Philippe, Legrand, Matthieu, Neely, Michael, Paiva, José-Artur, Payen, Didier, Rello, Jordi, Roger, Claire, Sjövall, Fredrik and Jung, Boris (2019). Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium. Anaesthesia Critical Care and Pain Medicine, 38 (6), 647-656. doi: 10.1016/j.accpm.2019.09.009
Tabah, Alexis, Bassetti, Matteo, Kollef, Marin H., Zahar, Jean-Ralph, Paiva, José-Artur, Timsit, Jean-Francois, Roberts, Jason A., Schouten, Jeroen, Giamarellou, Helen, Rello, Jordi, De Waele, Jan, Shorr, Andrew F., Leone, Marc, Poulakou, Garyphallia, Depuydt, Pieter and Garnacho-Montero, Jose (2019). Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP). Intensive Care Medicine, 46 (2), 245-265. doi: 10.1007/s00134-019-05866-w
Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?. Current Opinion in Anaesthesiology, 33 (1), 1-82. doi: 10.1097/aco.0000000000000810
Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4
Baptista, João Pedro, Roberts, Jason A., Sousa, Eduardo, Freitas, Ricardo, Devesa, Nuno and Pimentel, Jorge (2019). Attainment of therapeutic vancomycin level within the first 24 h: authors' response. Critical Care, 23 (1) 354, 354. doi: 10.1186/s13054-019-2639-7
Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780
Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 (3), 1-4. doi: 10.1159/000502474
Boidin, Clément, Bourguignon, Laurent, Cohen, Sabine, Roger, Claire, Lefrant, Jean-Yves, Roberts, Jason A., Allaouchiche, Bernard, Lepape, Alain, Friggeri, Arnaud and Goutelle, Sylvain (2019). Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori pharmacokinetic/pharmacodynamic target attainments in individual patients. Antimicrobial Agents and Chemotherapy, 63 (11) e00993-19, e00993-19. doi: 10.1128/aac.00993-19
Fox, Emma, Cheng, Vesa, Rawlins, Matthew, Dyer, John, De Keulenaer, Bart, Page, Michael M., Hoad, Kirsten and Roberts, Jason (2019). Pharmacokinetics of flucloxacillin during prolonged intermittent renal replacement therapy in a 76-year-old man. Journal of Chemotherapy, 31 (7-8), 1-5. doi: 10.1080/1120009X.2019.1681622
Abdul-Aziz, Mohd H., Shekar, Kiran and Roberts, Jason A. (2019). Antimicrobial therapy during ECMO – customised dosing with therapeutic drug monitoring: the way to go?. Anaesthesia Critical Care and Pain Medicine, 38 (5), 451-453. doi: 10.1016/j.accpm.2019.07.005
Mohd Sazlly, Lim S, Zainal Abidin, A., Liew, S.M., Roberts, J.A. and Sime, FB (2019). The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A systematic review and meta-analysis. Journal of Infection, 79 (6), 593-600. doi: 10.1016/j.jinf.2019.09.012
Douville, S. E., Callaway, L. K., Amoako, A., Roberts, J. and Eley, V. A. (2019). Reducing post-caesarean delivery surgical site infections: a narrative review. International Journal of Obstetric Anesthesia, 42, 76-86. doi: 10.1016/j.ijoa.2019.08.007
Gurunathan, Usha, Parker, Suzanne L., Maguire, Richard, Ramdath, Dale, Bijoor, Manu, Wallis, Steven C. and Roberts, Jason A. (2019). Population pharmacokinetics of periarticular ketorolac in adult patients undergoing total hip or total knee replacement surgery. Anesthesia and Analgesia, 129 (3), 701-708. doi: 10.1213/ANE.0000000000003377
Dhaese, Sofie A. M., Roberts, Jason A., Carlier, Mieke, Verstraete, Alain G., Stove, Veronique and De Waele, Jan J. (2019). Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients (vol 51, pg 594, 2018). International Journal of Antimicrobial Agents, 54 (3), 380-380. doi: 10.1016/j.ijantimicag.2019.07.022
Kanji, Salmaan, Roberts, Jason A., Xie, Jiao, Zelenitsky, Sheryl, Hiremath, Swapnil, Zhang, Guijun, Watpool, Irene, Porteous, Rebecca and Patel, Rakesh (2019). Vancomycin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis. Clinical Pharmacokinetics, 59 (3), 327-334. doi: 10.1007/s40262-019-00817-6
Baptista, João Pedro, Roberts, Jason A. and Udy, Andrew A. (2019). Augmented renal clearance: A real phenomenon with an uncertain cause. Anaesthesia Critical Care and Pain Medicine, 38 (4), 335-336. doi: 10.1016/j.accpm.2019.03.002
T.P. Wan, Winnie, Guerra Valero, Yarmarly, Choi, Gordon Y.S., Ordóñez Mejia, Jenny L., Wallis, Steven C., Joynt, Gavin M., Lipman, Jeffrey, Gomersall, Charles D. and Roberts, Jason A. (2019). In-vitro adsorption and sieving coefficient of ticarcillin-clavulanate during continuous haemofiltration. International Journal of Antimicrobial Agents, 54 (2), 261-264. doi: 10.1016/j.ijantimicag.2019.03.018
Dhaese, Sofie A.M., Roberts, Jason A., Carlier, M., Verstraete, Alain G., Stove, Veronique and DeWaele, J. J. (2019). Corrigendum to ‘Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients’ (International Journal of Antimicrobial Agents (2018) 51(4) (594–600), (S0924857917304491), (10.1016/j.ijantimicag.2017.12.015)). International Journal of Antimicrobial Agents, 54 (2), 271-271. doi: 10.1016/j.ijantimicag.2019.07.007
Dhaese, Sofie A.M., Thooft, Alexander D.J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2019). Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study. Journal of Critical Care, 52, 75-79. doi: 10.1016/j.jcrc.2019.04.013
Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 (10) e01265-19. doi: 10.1128/aac.01265-19
Sumi, Chandra Datta, Heffernan, Aaron J., Lipman, Jeffery, Roberts, Jason A. and Sime, Fekade B. (2019). What Antibiotic Exposures Are Required to Suppress the Emergence of Resistance for Gram‑Negative Bacteria? A Systematic Review. Clinical Pharmacokinetics, 58 (11), 1407-1443. doi: 10.1007/s40262-019-00791-z
Weber, Nicholas, Jackson, Kathryn, McWhinney, Brett, Ungerer, Jacobus, Kennedy, Glen, Lipman, Jeffrey and Roberts, Jason A. (2019). Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia. Journal of Infection and Chemotherapy, 25 (7), 503-508. doi: 10.1016/j.jiac.2019.02.014
Economou, Caleb J. P., Xie, Jiao, Comadira, Gregory, Richards, Brent, Tallott, Mandy, Wallis, Steven C., Ordoñez, Jenny, Lipman, Jeffrey and Roberts, Jason A. (2019). Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration. International Journal of Antimicrobial Agents, 54 (3), 351-355. doi: 10.1016/j.ijantimicag.2019.06.027
Cheng, Vesa, Rawlins, Matthew, Chang, Tim, Fox, Emma, Dyer, John, Allen, Chris, Litton, Edward, Page, Michael M., Hoad, Kirsten and Roberts, Jason A. (2019). Pharmacokinetics of benzylpenicillin (penicillin G) during prolonged intermittent renal replacement therapy. Chemotherapy, 64 (1), 1-5. doi: 10.1159/000499375
Setiawan, Eko, Wibowo, Yosi I., Setiadi, Adji P., Nurpatria, Yul'aini, Sosilya, Hernycane, Wardhani, Dian K., Cotta, Menino O., Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Implementasi Antimicrobial Stewardship Program di Kawasan Asia: Sebuah Kajian Sistematis. Indonesian Journal of Clinical Pharmacy, 8 (2), 141-156. doi: 10.15416/ijcp.2019.8.2.141
Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019). Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, 23 (1) 205, 205. doi: 10.1186/s13054-019-2483-9
Hagel, Stefan, Fiedler, Sandra, Hohn, Andreas, Brinkmann, Alexander, Frey, Otto R., Hoyer, Heike, Schlattmann, Peter, Kiehntopf, Michael, Roberts, Jason A., Pletz, Mathias W., Bloos, Frank, Angermair, Stefan, Bracht, Hendrik, Barth, Eberhard, Kluge, Stefan, Nierhaus, Axel, Motsch, Johann, Brenner, Thorsten, Annecke, Thorsten, Bach, Friedhelm, Weigand, Markus, Schappacher, Markus, Von Ameln-Mayerhofer, Andreas, Michels, Guido, Roehr, Anka, Fuchs, Thomas, Eichner, Sarah, Köng, Christina, Pinder, Nadine ... Braune, Anke (2019). Therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam to improve outcome in patients with sepsis (TARGET): a prospective, multi-centre, randomised controlled trial. Trials, 20 (1) 330, 330. doi: 10.1186/s13063-019-3437-x
Dhanani, Jayesh A., Roberts, Jason and Reade, Michael C (2019). Nebulized tranexamic acid therapy for hemoptysis associated with submassive pulmonary embolism. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 32 (1) jamp.2019.1534, 12-14. doi: 10.1089/jamp.2019.1534
Colin, Pieter J., Allegaert, Karel, Thomson, Alison H., Touw, Daan J., Dolton, Michael, de Hoog, Matthijs, Roberts, Jason A., Adane, Eyob D., Yamamoto, Masato, Santos-Buelga, Dolores, Martín-Suarez, Ana, Simon, Nicolas, Taccone, Fabio S., Lo, Yoke-Lin, Barcia, Emilia, Struys, Michel M. R. F. and Eleveld, Douglas J. (2019). Vancomycin pharmacokinetics throughout life: results from a pooled population analysis and evaluation of current dosing recommendations. Clinical Pharmacokinetics, 58 (6), 767-780. doi: 10.1007/s40262-018-0727-5
Tenorio-Cañamás, Teresa, Grau, Santiago, Luque, Sonia, Fortún, Jesús, Liaño, Fernando and Roberts, Jason A. (2019). Pharmacokinetics of micafungin in critically ill patients receiving continuous venovenous hemodialysis with high cutoff membranes. Therapeutic Drug Monitoring, 41 (3), 376-382. doi: 10.1097/FTD.0000000000000595
Heffernan, A. J., Germano, A., Sime, F. B., Roberts, Jason A. and Kimura, E. (2019). Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient?. European Journal of Clinical Pharmacology, 75 (9), 1219-1226. doi: 10.1007/s00228-019-02694-1
Schetz, Miet, De Jong, Audrey, Deane, Adam M., Druml, Wilfried, Hemelaar, Pleun, Pelosi, Paolo, Pickkers, Peter, Reintam-Blaser, Annika, Roberts, Jason, Sakr, Yasser and Jaber, Samir (2019). Obesity in the critically ill: a narrative review. Intensive Care Medicine, 45 (6), 757-769. doi: 10.1007/s00134-019-05594-1
Roberts, Jason A., Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Sjövall, Fredrik (2019). Defining optimal dosing of ciprofloxacin in patients with septic shock. Journal of Antimicrobial Chemotherapy, 74 (6) dkz069, 1662-1669. doi: 10.1093/jac/dkz069
Lim, Sazlyna Mohd Sazlly, Sime, Fekade Bruck and Roberts, Jason (2019). Multidrug-resistant Acinetobacter baumannii infections: current evidence on treatment options and role of PK/PD in dose optimization. International Journal of Antimicrobial Agents, 53 (6), 726-745. doi: 10.1016/j.ijantimicag.2019.02.016
Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018
O'Brien, Daniel W., Cotta, Menino O., Choo, Lyn, Fowler, Stephen, Downey, Maria, Fisquet, Stephanie, Tan, Ivy and Roberts, Jason A. (2019). Dexmedetomidine prescribing in Australian intensive care units: an observational study. Journal of Pharmacy Practice and Research, 49 (5) jppr.1529, 477-481. doi: 10.1002/jppr.1529
Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161
Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752
Roberts, Jason A., Roger, Claire and De Waele, Jan J. (2019). Personalized antibiotic dosing for the critically ill. Intensive Care Medicine, 45 (5), 715-718. doi: 10.1007/s00134-019-05522-3
Setiawan, Eko, Widyati,, Marpaung, Ferdy Royland, Sukandar, Edy, Susaniwati,, Lukas, Dwi Lily, Wijono, Heru, Warindra, Taufin, Kurniawan, Roni, Wibowo, Tjipto, Hendradi, Wahyu, Costa, Menino Osbert, Abdul-Aziz, Mohd-Hafiz and Roberts, Jason (2019). Narrative study on pharmacokinetics of antibiotics among critically ill patients: the implication on the pharmacokinetics-pharmacodynamics target attainment. Pharmaceutical Sciences and Research, 6 (1). doi: 10.7454/psr.v6i1.4274
Zhang, Ping, Curley, Cameron I., Mudie, Kari, Nakagaki, Midori, Hill, Geoffrey R., Roberts, Jason A. and Tey, Siok-Keen (2019). Effect of plasmapheresis on ATG (Thymoglobulin) clearance prior to adoptive T cell transfer. Bone Marrow Transplantation, 54 (12), 2110-2116. doi: 10.1038/s41409-019-0505-5
Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2019). Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, 53 (3), 234-245. doi: 10.1016/j.ijantimicag.2018.11.011
Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68.
Dimopoulos, George, Koulenti, Despoina, Parker, Suzanne L, Roberts, Jason A, Arvaniti, Kostoula and Poulakou, Garyphalia (2019). Intravenous fosfomycin for the treatment of multidrug resistant pathogens: what is the evidence on dosing regimens?. Expert Review of Anti-infective Therapy, 17 (3) 14787210.2019.1573669, 201-210. doi: 10.1080/14787210.2019.1573669
Paul, Sanjoy Ketan, Roberts, Jason A., Lipman, Jeffrey, Deans, Renae and Samanta, Mayukh (2019). A robust statistical approach to analyse population pharmacokinetic data in critically ill patients receiving renal replacement therapy. Clinical Pharmacokinetics, 58 (2), 263-270. doi: 10.1007/s40262-018-0690-1
Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021
Dhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434
Cheng, Vesa, Abdul-Aziz, Mohd H., Roberts, Jason A. and Shekar, Kiran (2019). Overcoming barriers to optimal drug dosing during ECMO in critically ill adult patients. Expert Opinion on Drug Metabolism & Toxicology, 15 (2), 103-112. doi: 10.1080/17425255.2019.1563596
Williams, Paul, Beall, Gareth, Cotta, Menino Osbert and Roberts, Jason A. (2019). Antimicrobial dosing in critical care: a pragmatic adult dosing nomogram. International Journal of Antimicrobial Agents, 55 (2) 105837, 105837. doi: 10.1016/j.ijantimicag.2019.10.018
Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Maqbool, Faheem, Roberts, Jason A. and Falconer, James Robert (2019). Solid nanoparticles for oral antimicrobial drug delivery: a review. Drug Discovery Today, 24 (3), 858-866. doi: 10.1016/j.drudis.2019.01.004
Lefrant, Jean-Yves, Lorne, Emmanuel, Asehnoune, Karim, Ausset, Silvain, Beaulieu, Pierre, Biais, Matthieu, Brichant, Jean-Francois, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dadure, Christophe, Dahmani, Souhayl, David, Jean-Stephane, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Hanouz, Jean-Luc, Joannes-Boyau, Olivier, Kipnis, Eric, Laudenbach, Vincent, Le Guen, Morgan, Legrand, Matthieu, Lescot, Thomas, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sebastien, Pirracchio, Romain, Roberts, Jason ... Capdevila, Xavier (2019). Une voie originale pour une voix originale. Anesthesie & Reanimation, 5 (1), 1-3. doi: 10.1016/j.anrea.2018.11.001
Williams, Paul, Cotta, Menino Osbert and Roberts, Jason A. (2019). Pharmacokinetics/Pharmacodynamics of β-Lactams and therapeutic drug monitoring: from theory to practical issues in the intensive care unit. Seminars in Respiratory and Critical Care Medicine, 40 (4), 476-487. doi: 10.1055/s-0039-1693498
Mabilat, Claude, Gros, Marie Francoise, Nicolau, David, Mouton, Johan W., Textoris, Julien, Roberts, Jason A., Cotta, Menino O., van Belkum, Alex and Caniaux, Isabelle (2019). Diagnostic and medical needs for therapeutic drug monitoring of antibiotics. European Journal of Clinical Microbiology and Infectious Diseases, 39 (5), 791-797. doi: 10.1007/s10096-019-03769-8
Richter, Daniel C., Frey, Otto, Röhr, Anka, Roberts, Jason A., Köberer, Andreas, Fuchs, Thomas, Papadimas, Nikolaos, Heinzel-Gutenbrunner, Monika, Brenner, Thorsten, Lichtenstern, Christoph, Weigand, Markus A. and Brinkmann, Alexander (2019). Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill patients: a retrospective analysis of four years of clinical experience. Infection, 47 (6), 1001-1011. doi: 10.1007/s15010-019-01352-z
Kerz, Thomas, Von Loewenich, Friederike D., Roberts, Jason, Neulen, Axel and Ringel, Florian (2018). Cerebrospinal fluid penetration of very high-dose meropenem: a case report. Annals of Clinical Microbiology and Antimicrobials, 17 (1) 47, 47. doi: 10.1186/s12941-018-0299-0
Jamal, Janattul-Ain, Roger, Claire and Roberts, Jason A. (2018). Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics. Anaesthesia Critical Care & Pain Medicine, 37 (6), 515-517. doi: 10.1016/j.accpm.2018.10.006
Toulouse, Elisabeth, Masseguin, Christophe, Lafont, Brigitte, McGurk, Gordon, Harbonn, Anna, Roberts, Jason A., Granier, Sophie, Dupeyron, Arnaud and Bazin, Jean Etienne (2018). French legal approach to clinical research. Anaesthesia Critical Care and Pain Medicine, 37 (6), 607-614. doi: 10.1016/j.accpm.2018.10.013
Rawlins, Matthew, Cheng, Vesa, Raby, Edward, Dyer, John, Regli, Adrian, Ingram, Paul, McWhinney, Brett C., Ungerer, Jacobus P. J. and Roberts, Jason A. (2018). Pharmacokinetics of ceftolozane-tazobactam during prolonged intermittent renal replacement therapy. Chemotherapy, 63 (4), 203-206. doi: 10.1159/000493196
Heffernan, Aaron J., Sime, Fekade B., Taccone, Fabio S. and Roberts, Jason A. (2018). How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients. Current Opinion in Infectious Diseases, 31 (6), 1-565. doi: 10.1097/QCO.0000000000000494
Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration. International Journal of Antimicrobial Agents, 52 (4), 506-509. doi: 10.1016/j.ijantimicag.2018.07.008
Wong, Gloria, Briscoe, Scott, McWhinney, Brett, Ally, Mumtaz, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A (2018). Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures. Journal of Antimicrobial Chemotherapy, 73 (11), 3087-3094. doi: 10.1093/jac/dky314
Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18
Lefrant, Jean-Yves, Lorne, Emmanuel, Asehnoune, Karim, Ausset, Sylvain, Beaulieu, Pierre, Biais, Matthieu, Brichant, Jean-Francois, Charbit, Beny, Constantin, Jean-Michel, Cuvillon, Philippe, Dadure, Christophe, Dahmani, Souhayl, David, Jean-Stephane, Fuchs-Buder, Thomas, Geeraerts, Thomas, Godier, Anne, Hanouz, Jean-Luc, Joannes-Boyau, Olivier, Kipnis, Eric, Laudenbach, Vincent, Le Guen, Morgan, Legrand, Matthieu, Lescot, Thomas, Marret, Emmanuel, Mongardon, Nicolas, Ouattara, Alexandre, Pierre, Sebastien, Roberts, Jason, Schneider, Antoine ... Capdevila, Xavier (2018). Determining the editorial policy of Anaesthesia Critical Care and Pain Medicine (ACCPM). Anaesthesia Critical Care & Pain Medicine, 37 (4), 299-301. doi: 10.1016/j.accpm.2018.07.001
Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7
Jacobs, Alexandra, Taccone, Fabio Silvio, Roberts, Jason A., Jacobs, Frédérique, Wolff, Fleur, Cotton, Frederic, Creteur, Jacques, Vincent, Jean-Louis and Hites, Maya (2018). β-lactam dosage regimens in septic patients with augmented renal clearance. Antimicrobial Agents and Chemotherapy, 62 (9) e02534-17, AAC.02534-17. doi: 10.1128/AAC.02534-17
Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003
Heil, Emily L., Nicolau, David P., Farkas, Andras, Roberts, Jason A. and Thom, Kerri A. (2018). Pharmacodynamic target attainment for cefepime, meropenem and piperacillin/tazobactam using a pharmacokinetic/pharmacodynamic-based dosing calculator in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 (9) e01008-18, AAC.01008-18. doi: 10.1128/AAC.01008-18
Rhodes, Nathaniel J., Liu, Jiajun, Lipman, Jeffrey and Roberts, Jason A. (2018). The authors reply. Critical Care Medicine, 46 (7), e725-e726. doi: 10.1097/CCM.0000000000003164
Tsai, D., Stewart, P. C., Hewagama, S., Krishnaswamy, S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2018). Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis. Anaesthesia and Intensive Care, 46 (4), 374-380. doi: 10.1177/0310057X1804600405
Abdul-Aziz, Mohd H., Driver, Elicia, Lipman, Jeffrey and Roberts, Jason A. (2018). New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods. Expert Opinion on Drug Metabolism and Toxicology, 14 (7), 1-16. doi: 10.1080/17425255.2018.1484452
Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018). Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47, 15-20. doi: 10.1016/j.jcrc.2018.05.016
Kanji, Salmaan, Roberts, Jason A., Xie, Jiao, Alobaid, Abdulaziz, Zelenitsky, Sheryl, Hiremath, Swapnil, Zhang, Guijun, Watpool, Irene, Porteous, Rebecca and Patel, Rakesh (2018). Piperacillin population pharmacokinetics in critically ill adults during sustained low-efficiency dialysis. Annals of Pharmacotherapy, 52 (10), 106002801877377-973. doi: 10.1177/1060028018773771
Vickers, Mark L., Dulhunty, Joel M., Ballard, Emma, Chapman, Paul, Muller, Michael, Roberts, Jason A. and Cotta, Menino O. (2018). Risk factors for multidrug-resistant Gram-negative infection in burn patients. ANZ Journal of Surgery, 88 (5), 480-485. doi: 10.1111/ans.14144
Bukkems, Laura H., Roger, Claire, Hodiamont, Caspar J., Lefrant, Jean-Yves, Juffermans, Nicole P., Roberts, Jason A. and van Hest, Reinier M. (2018). Predictive performance of a gentamicin population pharmacokinetic model in two Western populations of critically ill patients. International Journal of Antimicrobial Agents, 52 (2), 218-225. doi: 10.1016/j.ijantimicag.2018.04.016
Maseda, Emilio, Grau, Santiago, Luque, Sonia, Castillo-Mafla, Maria-Pilar, Suárez-de-la-Rica, Alejandro, Montero-Feijoo, Ana, Salgado, Patricia, Gimenez, Maria-Jose, García-Bernedo, Carlos A., Gilsanz, Fernando and Roberts, Jason A. (2018). Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients. Critical Care, 22 (1) 94, 94. doi: 10.1186/s13054-018-2019-8
Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). Pharmacokinetics of intravenous posaconazole in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 (6) e00242-18, e00242-18. doi: 10.1128/AAC.00242-18
Heffernan, A. J., Sime, F. B., Lipman, J. and Roberts, J. A. (2018). Individualising therapy to minimize bacterial multidrug resistance. Drugs, 78 (6), 621-641. doi: 10.1007/s40265-018-0891-9
Tängdén, Thomas, Cojutti, Pier Giorgio, Roberts, Jason A. and Pea, Federico (2018). Valganciclovir pharmacokinetics in patients receiving oral prophylaxis following kidney transplantation and model-based predictions of optimal dosing regimens. Clinical Pharmacokinetics, 57 (11), 1-7. doi: 10.1007/s40262-018-0638-5
Economou, Caleb J. P., Kielstein, Jan T., Czock, David, Xie, Jiao, Field, Jonathan, Richards, Brent, Tallot, Mandy, Visser, Adam, Koenig, Christina, Hafer, Carsten, Schmidt, Julius J., Lipman, Jeffrey and Roberts, Jason A. (2018). Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy. International Journal of Antimicrobial Agents, 52 (2), 151-157. doi: 10.1016/j.ijantimicag.2018.03.001
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 (6), 1647-1650. doi: 10.1093/jac/dky057
Cheng, Vesa, Abdul-Aziz, Mohd-Hafiz, Roberts, Jason A. and Shekar, Kiran (2018). Optimising drug dosing in patients receiving extracorporeal membrane oxygenation. Journal of Thoracic Disease, 10 (Suppl 5), S629-S641. doi: 10.21037/jtd.2017.09.154
Yadav, Rajbharan, Rogers, Kate E., Bergen, Phillip J., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens againstfor patients with altered pharmacokineticsthe hollow-fiber infection model and mechanism-based modeling. Antimicrobial Agents and Chemotherapy, 62 (5) e00078, e00078-18. doi: 10.1128/AAC.00078-18
Stewart, A., Roberts, J. A., Wallis, S. C., Allworth, A. M., Legg, A. and McCarthy, K. L. (2018). Evidence of clinical response and stability of Ceftolozane/Tazobactam used to treat a carbapenem-resistant Pseudomonas Aeruginosa lung abscess on an outpatient antimicrobial program. International Journal of Antimicrobial Agents, 51 (6), 941-942. doi: 10.1016/j.ijantimicag.2018.02.008
Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018). Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 (6), 407-423. doi: 10.4155/bio-2017-0269
Minichmayr, Iris K., Roberts, Jason A., Frey, Otto R., Roehr, Anka C., Kloft, Charlotte and Brinkmann, Alexander (2018). Development of a dosing nomogram for continuous-infusion meropenem in critically ill patients based on a validated population pharmacokinetic model. The Journal of Antimicrobial Chemotherapy, 73 (5), 1330-1339. doi: 10.1093/jac/dkx526
Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul-Aziz, Mohd H., Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffery and Roberts, Jason A. (2018). Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine, 46 (2), 236-243. doi: 10.1097/CCM.0000000000002836
Roberts, Jason A. (2018). Beta-Lactam Therapeutic Drug Monitoring in the Critically Ill Children: Big Solution for Infections in Small People?. Critical Care Medicine, 46 (2), 335-337. doi: 10.1097/CCM.0000000000002862
Leguelinel-Blache, Géraldine, Nguyen, Tri-Long, Louart, Benjamin, Poujol, Hélène, Lavigne, Jean-Philippe, Roberts, Jason A, Muller, Laurent, Kinowski, Jean-Marie, Roger, Claire and Lefrant, Jean-Yves (2018). Impact of Quality Bundle Enforcement by a Critical Care Pharmacist on Patient Outcome and Costs. Critical Care Medicine, 46 (2), 199-207. doi: 10.1097/CCM.0000000000002827
Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018). A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148, 324-333. doi: 10.1016/j.jpba.2017.10.023
Braune, Stephan, König, Christina, Roberts, Jason A., Nierhaus, Axel, Steinmetz, Oliver, Baehr, Michael, Kluge, Stefan and Langebrake, Claudia (2018). Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study. Critical Care (London, England), 22 (1) 25, 1-10. doi: 10.1186/s13054-018-1940-1
Heffernan, A., Lipman, J. and Roberts, J. (2018). Re: 'Is a randomized trial of a short course of aminoglycoside added to β-lactam antibiotics for empirical treatment in critically ill patients with sepsis justified?' Pharmacokinetic/pharmacodynamic considerations. Clinical Microbiology and Infection, 24 (6), 666-667. doi: 10.1016/j.cmi.2017.12.019
Bergen, Phillip J., Bulitta, Jürgen B., Sime, Fekade B., Lipman, Jeffrey, McGregor, Megan J., Millen, Nada, Paterson, David L., Kirkpatrick, Carl M. J., Roberts, Jason A. and Landersdorfer, Cornelia B. (2018). Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli. Diagnostic Microbiology and Infectious Disease, 91 (1), 69-76. doi: 10.1016/j.diagmicrobio.2017.12.019
Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w
Tsai, D., Udy, A. A., Stewart, P. C., Gourley, S., Morick, N. M., Lipman, J. and Roberts, J. A. (2018). Prevalence of augmented renal clearance and performance of glomerular filtration estimates in Indigenous Australian patients requiring intensive care admission. Anaesthesia and Intensive Care, 46 (1), 42-50. doi: 10.1177/0310057X1804600107
König, Christina, Röhr, Anka C., Frey, Otto R., Brinkmann, Alexander, Roberts, Jason A., Wichmann, Dominic, Braune, Stephan, Kluge, Stefan and Nierhaus, Axel (2018). In vitro removal of anti-infective agents by a novel cytokine adsorbent system. International Journal of Artificial Organs, 42 (2), 57-64. doi: 10.1177/0391398818812601
De Waele, Jan J., Akova, Murat, Antonelli, Massimo, Canton, Rafael, Carlet, Jean, De Backer, Daniel, Dimopoulos, George, Garnacho-Montero, José, Kesecioglu, Jozef, Lipman, Jeffrey, Mer, Mervyn, Paiva, José-Artur, Poljak, Mario, Roberts, Jason A., Rodriguez Bano, Jesus, Timsit, Jean-François, Zahar, Jean-Ralph and Bassetti, Matteo (2017). Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Medicine, 44 (2), 189-196. doi: 10.1007/s00134-017-5036-1
Dhaese, Sofie A. M., Roberts, Jason A., Carlier, Mieke, Verstraete, Alain G., Stove, Veronique and De Waele, Jan J. (2017). Population pharmacokinetics of piperacillin continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 51 (4), 594-600. doi: 10.1016/j.ijantimicag.2017.12.015
Byrne, Catherine J., Parton, Ted, McWhinney, Brett, Fennell, Jerome P., O'Byrne, Philomena, Deasy, Evelyn, Egan, Sean, Enright, Helen, Desmond, Ronan, Ryder, Sheila A., D'Arcy, Deirdre M., McHugh, Johnny and Roberts, Jason A. (2017). Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy. The Journal of Antimicrobial Chemotherapy, 73 (4), 995-1003. doi: 10.1093/jac/dkx473
Abbott, Iain J., Meletiadis, Joseph, Belghanch, Imane, Wijma, Rixt A., Kanioura, Lamprini, Roberts, Jason A., Peleg, Anton Y. and Mouton, Johan W. (2017). Fosfomycin efficacy and emergence of resistance among Enterobacteriaceae in an in vitro dynamic bladder infection model. The Journal of Antimicrobial Chemotherapy, 73 (3), 709-719. doi: 10.1093/jac/dkx441
Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030
Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017). Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 (1) 283, 1-3. doi: 10.1186/s13054-017-1871-2
Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17
Global Alliance for Infections in Surgery Working Group and Roberts, Jason (2017). A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway. Surgical Infections, 18 (8), 846-853. doi: 10.1089/sur.2017.219
Roger, Claire, Roberts, Jason A. and Muller, Laurent (2017). Clinical pharmacokinetics and pharmacodynamics of oxazolidinones. Clinical Pharmacokinetics, 57 (5), 1-17. doi: 10.1007/s40262-017-0601-x
Sinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14.
Udy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017). The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123, 65-74. doi: 10.1016/j.addr.2017.09.019
Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3
Sjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017). Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 (1) dkx330, 191-198. doi: 10.1093/jac/dkx330
Rello, J., Rouby, J. J., Sole-Lleonart, C., Chastre, J., Blot, S., Luyt, C. E., Riera, J., Vos, M. C., Monsel, A., Dhanani, J. and Roberts, J. A. (2017). Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients. Clinical Microbiology and Infection, 23 (9), 640-646. doi: 10.1016/j.cmi.2017.03.018
Rello, J., Sole-Lleonart, C., Rouby, J. -J., Chastre, J., Blot, S., Poulakou, G., Luyt, C. -E., Riera, J., Palmer, L. B., Pereira, J. M., Felton, T., Dhanani, J., Bassetti, M., Welte, T. and Roberts, J. A. (2017). Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. Clinical Microbiology and Infection, 23 (9), 629-639. doi: 10.1016/j.cmi.2017.04.011
Sartelli, M., Weber, D. G., Ruppé, E., Bassetti, M., Wright, B. J., Ansaloni, L., Catena, F., Coccolini, F., Abu-Zidan, F. M., Coimbra, R., Moore, E. E., Moore, F. A., Maier, R. V., De Waele, J. J., Kirkpatrick, A. W., Griffiths, E. A., Eckmann, C., Brink, A. J., Mazuski, J. E., May, A. K., Sawyer, R. G., Mertz, D., Montravers, P., Kumar, A., Roberts, J. A., Vincent, J. L., Watkins, R. R., Lowman, W., Spellberg, B. ... Viale, P. (2017). Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y. World Journal of Emergency Surgery, 12 (1) 35, 35. doi: 10.1186/s13017-017-0147-0
Xie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017). Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 (8) e00345-17, e00345-17. doi: 10.1128/AAC.00345-17
Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018
Sartelli, Massimo, Labricciosa, Francesco M., Barbadoro, Pamela, Pagani, Leonardo, Ansaloni, Luca, Brink, Adrian J., Carlet, Jean, Khanna, Ashish, Chichom-Mefire, Alain, Coccolini, Federico, Di Saverio, Salomone, May, Addison K. , Viale, Pierluig, Watkins, Richard R., Scudeller, Luigia, Abbo, Lilian M., Abu-Zidan, Fikri M., Adesunkanmi, Abdulrashid K., Al-Dahir, Sara, Al-Hasan, Majdi N., Alis, Halil, Alves, Carlos, Araujo da Silva, Andre .R., Augustin, Goran, Bala, Miklosh, Barie, Philip S., Beltran, Marcelo A., Bhangu, Aneel, Bouchra, Belefquih ... Catena, Fausto (2017). The Global Alliance for Infections in Surgery: Defining a model for antimicrobial stewardship-results from an international cross-sectional survey. World Journal of Emergency Surgery, 12 (1) 34, 34. doi: 10.1186/s13017-017-0145-2
Bruggink, Leesa D., Moselen, Jean M., Roberts, Jason A. and Marshall, John A. (2017). Evolutionary changes in the capsid P2 region of Australian strains of the norovirus GII.Pe_GII.4. Journal of Medical Microbiology, 66 (7) 000531, 1014-1022. doi: 10.1099/jmm.0.000531
Roberts, Jason, Hobday, Linda, Ibrahim, Aishah, Aitken, Thomas and Thorley, Bruce (2017). Australian National Enterovirus Reference Laboratory annual report, 2014. Communicable diseases intelligence quarterly report, 41 (2), E161-E180.
Sulaiman, Helmi, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2017). Pharmacokinetic/pharmacodynamics-optimized antimicrobial therapy in patients with hospital-acquired pneumonia/ventilator-associated pneumonia. Seminars in Respiratory and Critical Care Medicine, 38 (3) 01275, 271-286. doi: 10.1055/s-0037-1602716
Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019
Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017). Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 (6), 876-882. doi: 10.1093/bja/aex026
Byrne, Catherine J., Roberts, Jason A., McWhinney, Brett, Fennell, Jerome P., O'Byrne, Philomena, Deasy, Evelyn, Egan, Sean, Desmond, Ronan, Enright, Helen, Ryder, Sheila A., D'Arcy, Deirdre M. and McHugh, Johnny (2017). Variability in trough total and unbound teicoplanin concentrations and achievement of therapeutic drug monitoring targets in adult patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 61 (6) e02466-16, e02466-16. doi: 10.1128/AAC.02466-16
Sole-Lleonart, Candela, Rouby, Jean-Jacques, Blot, Stijn, Poulakou, Garyfallia, Chastre, Jean, Palmer, Lucy B., Bassetti, Matteo, Luyt, Charles-Edouard, Pereira, Jose M., Riera, Jordi, Felton, Tim, Dhanani, Jayesh, Welte, Tobias, Garcia-Alamino, Jose M., Roberts, Jason A. and Rello, Jordi (2017). Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis. Anesthesiology, 126 (5), 890-908. doi: 10.1097/ALN.0000000000001570
Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009
Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16
Konig, Christina, Braune, Stephan, Roberts, Jason A., Nierhaus, Axel, Steinmetz, Oliver M., Baehr, Michael, Frey, Otto R., Langebrake, Claudia and Kluge, Stefan (2017). Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis. Journal of Antimicrobial Chemotherapy, 72 (5), 1433-1440. doi: 10.1093/jac/dkw592
Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x
Coulter, Sonali, Roberts, Jason A., Hajkowicz, Krispin and Halton, Kate (2017). The use of bloodstream infection mortality to measure the impact of antimicrobial stewardship interventions: assessing the evidence. Infectious Disease Reports, 9 (1), 8-12. doi: 10.4081/idr.2017.6849
Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022
Byrne, C. J., Roberts, J. A., McWhinney, B., Ryder, S. A., Fennell, J. P., O'Byrne, P., Deasy, E., Egan, S., Desmond, R., Enright, H., D'Arcy, D. M. and McHugh, J. (2017). Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy. Clinical Microbiology and Infection, 23 (9), 674.e7-674.e13. doi: 10.1016/j.cmi.2017.02.032
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16
Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017). Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 (4), 395-402. doi: 10.1016/j.ijantimicag.2016.12.014
Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017). Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 (5), 221-226. doi: 10.1089/ars.2016.6845
Roberts, Jason A., Kumar, Anand and Lipman, Jeffrey (2017). Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 (2), 331-336. doi: 10.1097/CCM.0000000000002210
Sime, Fekade Bruck, Johnson, Adam, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A. Bruce, Walters, Kathie Ann, Lipman, Jeffrey, Hope, William W. and Roberts, Jason A. (2017). Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy. Antimicrobial Agents and Chemotherapy, 61 (1) e01763-16, e01763-16. doi: 10.1128/AAC.01763-16
Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017). Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 (1), 137-144. doi: 10.1089/neu.2015.4328
Roger, C., Wallis, S.C., Muller, L., Saissi, G., Lipman, J., Bruggemann, R.J., Lefrant, J.-Y. and Roberts, J.A. (2016). Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration. Clinical Pharmacokinetics, 56 (9), 1-12. doi: 10.1007/s40262-016-0495-z
Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 (2), 231-239. doi: 10.1097/QCO.0000000000000348
Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (6), 748-752. doi: 10.1016/j.ijantimicag.2016.09.021
Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis. Antimicrobial Agents and Chemotherapy, 60 (12), 7402-7406. doi: 10.1128/AAC.01657-16
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 (11), 6550-6557. doi: 10.1128/AAC.01088-16
Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016). Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 (21), 2235-2242. doi: 10.4155/bio-2016-0159
Farkas, Andras, Daroczi, Gergely, Villasurda, Phillip, Dolton, Michael, Nakagaki, Midori and Roberts, Jason A. (2016). Comparative evaluation of the predictive performances of three different structural population pharmacokinetic models to predict future voriconazole concentrations. Antimicrobial Agents and Chemotherapy, 60 (11), 6806-6812. doi: 10.1128/AAC.00970-16
Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016). Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 (5), 542-546. doi: 10.1016/j.ijantimicag.2016.08.015
Veringa, Anette, Sturkenboom, Marieke G. G., Dekkers, Bart G. J., Koster, Remco A., Roberts, Jason A., Peloquin, Charles A., Touw, Daan J. and Alffenaar, Jan-Willem C. (2016). LC-MS/MS for therapeutic drug monitoring of anti-infective drugs. Trends in Analytical Chemistry, 84, 34-40. doi: 10.1016/j.trac.2015.11.026
Dhanani, Jayesh, Fraser, John F., Chan, Hak-Kim, Rello, Jordi, Cohen, Jeremy and Roberts, Jason A. (2016). Fundamentals of aerosol therapy in critical care. Critical Care, 20 (1) 269, 269. doi: 10.1186/s13054-016-1448-5
Zelenitsky, S. A., Lawson, C., Calic, D., Ariano, R. E., Roberts, J. A., Lipman, J. and Zhanel, G. G. (2016). Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery. Journal of Antimicrobial Chemotherapy, 71 (10) dkw247, 2902-2908. doi: 10.1093/jac/dkw247
Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2016). Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study. Critical Care Medicine, 44 (10), e923-e929. doi: 10.1097/CCM.0000000000001823
Tabah, Alexis, Lipman, Jeffrey and Roberts, Jason A. (2016). Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?. Anaesthesia, Critical Care and Pain Medicine, 35 (5), 311-312. doi: 10.1016/j.accpm.2016.08.002
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35, 231-239. doi: 10.1016/j.jcrc.2016.06.022
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Erratum: is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients? The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. Journal of Critical Care, 35, 230-230. doi: 10.1016/j.jcrc.2016.06.021
Garcia-De-Lorenzo, A., Luque, S., Grau, S., Agrifoglio, A., Cachafeiro, L., Herrero, E., Asensio, M. J., Sanchez, S. M. and Roberts, J. A. (2016). Comparative population plasma and tissue pharmacokinetics of micafungin in critically ill patients with severe burn injuries and patients with complicated intra-abdominal infection. Antimicrobial Agents and Chemotherapy, 60 (10), 5914-5921. doi: 10.1128/AAC.00727-16
Osthoff, Michael, Siegemund, Martin, Balestra, Gianmarco, Abdul-Aziz, Mohd H. and Roberts, Jason A. (2016). Prolonged administration of beta-lactam antibiotics - a comprehensive review and critical appraisal. Swiss Medical Weekly, 146, w14368-w14368. doi: 10.4414/smw.2016.14368
Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016). Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 (10), 1535-1545. doi: 10.1007/s00134-015-4188-0
Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016). Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 (6), 681-691. doi: 10.1164/rccm.201601-0024OC
Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2016). Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling. Journal of Antimicrobial Chemotherapy, 71 (9), 2509-2520. doi: 10.1093/jac/dkw153
Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016). Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 (9), 1961-1975. doi: 10.1016/j.clinthera.2016.07.093
Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016). Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 (9), 957-965.
Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A, Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratala, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L. and Brozek, Jan L. (2016). Executive summary: management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clinical Infectious Diseases, 63 (5), 575-582. doi: 10.1093/cid/ciw504
Kalil, Andre C., Metersky, Mark L., Klompas, Michael, Muscedere, John, Sweeney, Daniel A., Palmer, Lucy B., Napolitano, Lena M., O'Grady, Naomi P., Bartlett, John G., Carratala, Jordi, El Solh, Ali A., Ewig, Santiago, Fey, Paul D., File, Thomas M., Jr., Restrepo, Marcos I., Roberts, Jason A., Waterer, Grant W., Cruse, Peggy, Knight, Shandra L. and Brozek, Jan L. (2016). Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clinical Infectious Diseases, 63 (5), E61-E111. doi: 10.1093/cid/ciw353
Hanrahan, Timothy P., Lipman, Jeffrey and Roberts, Jason A. (2016). Antibiotic dosing in obesity: a BIG challenge. Critical Care, 20 (240) 240, 240. doi: 10.1186/s13054-016-1426-y
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. Journal of Critical Care, 34, 95-102. doi: 10.1016/j.jcrc.2016.04.005
Sole-Lleonart, Candela, Rouby, Jean-Jacques, Chastre, Jean, Poulakou, Garyfallia, Palmer, Lucy B., Blot, Stijn,