Professor Jeffrey Lipman

Featured projects	Duration
Exploring the impact of altered and variable antimicrobial pharmacokinetics on bacterial killing and emergence of bacterial resistance. National Health and Medical Research Council
Develop informed consumer groups whose members participate as partners in CRE research projects and processes
Antibiotic penetration into epithelial lining fluid of mechanically ventilated patients with VAP and CAP.
Development of clinical practice guidelines on antimicrobial dosing incorporating new knowledge generated by the CRE REDUCE.
Exploring population variability of antimicrobial epithelial lining fluid penetration in patients with VAP.
PK studies of antimicrobials in patients with VAP, CAP/ PK of antimicrobials National Health and Medical Research Council
SaMpling Antibiotics in Renal Replacement Therapy (SMARRT). National Health and Medical Research Council
Therapeutic Drug Monitoring National Health and Medical Research Council
Antimicrobial pharmacokinetics in patients with cystic fibrosis, lung and bone marrow transplant. National Health and Medical Research Council
BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients National Health and Medical Research Council
Pharmacokinetics of Flucloxacillin and Lincomycin in burns patients. National Health and Medical Research Council
Pharmacokinetics of antifungals in intensive care patients. National Health and Medical Research Council
Pharmacokinetics of antimicrobials in critically ill paediatric patients. National Health and Medical Research Council
Pharmacokinetics of antimicrobials in critically ill obese patients National Health and Medical Research Council
Therapeutic drug monitoring optimisation of antimicrobial exposures for critically ill, burns and transplant patients.
Continuous versus intermittent beta-lactams administration in critically ill patients with sepsis not receiving renal replacement therapy.

Rello, Jordi, Lipman, Jeffrey and Lisboa, Thiago Sepsis management: PIRO and MODS. Springer-Verlag Berlin Heidelberg, 2012. doi:10.1007/978-3-642-03519-7

Denny, Kerina J., Lipman, Jeffrey and Roberts, Jason A. (2017). Cephalothin and cefazolin. In Kucers the use of antibiotics: a clinical review of antibacterial, antifungal, antiparasitic, and antiviral drugs, seventh edition (pp. 347-360) Boca Raton, FL, United States: CRC Press. doi:10.1201/9781315152110

Udy, Andrew and Lipman, Jeffrey (2012). Importance of high creatinine clearance for antibacterial treatment in sepsis. In Jordi Rello, Jeffrey Lipman and Thiago Lisboa (Ed.), Sepsis management: PIRO and MODS (pp. 171-197) Berlin, Germany: Springer. doi:10.1007/978-3-642-03519-7_12

Carvajal, Carlos, Rello, Jordi and Lipman, Jeffrey (2011). Candida pneumonia in patients with hematological neoplasia. In Elie Azoulay (Ed.), Pulmonary involvement in patients with hematological malignancies (pp. 349-356) Berlin, Germany: Springer - Verlag. doi:10.1007/978-3-642-15742-4_28

Ulldemolins, Marta, Roberts, Jason, Varghese, Julie and Lipman, Jeffrey (2010). Antibiotic dosing in critically ill patients. In Vineet Nayar, J. V. Peter, Roop Kishen and S. Srinivas (Ed.), Critical Care Update 2009 (pp. 128-142) Daryaganj, New Delhi, India: Jaypee Brothers Medical Publishers.

Udy, Andrew, Roberts, Jason and Lipman, Jeffrey (2010). Augmented renal clearance: Unraveling the mystery of elevated antibiotic clearance. In J.-L. Vincent (Ed.), Yearbook of Intensive Care and Emergency Medicine 2010 (pp. 495-506) Brussels, Belgium: Springer Verlag. doi:10.1007/978-3-642-10286-8

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2009). Avoiding toxicity of antibiotics. In Jean-Daniel Chiche and Leanne M. Aitken (Ed.), Patient safety and quality of care in intensive care medicine (pp. 291-304) Berlin, Germany: Medizinisch Wissenschaftliche Verlagsgesellschaft.

Brown, Anthony F.T. and Lipman, Jeffrey (2008). Prehospital Care. In Mechanical Ventilation: Clinical Applications and Pathophysiology (pp. 307-319) : Elsevier Inc.. doi:10.1016/B978-0-7216-0186-1.50032-6

Cohen, Jeremy and Lipman, Jeffrey (2008). Use and abuse of antibiotics. In Nigel R. Webster and Helen F. Galley (Ed.), Anaesthesia science (pp. 128-136) Malden, MA, United States: Blackwell Publishing . doi:10.1002/9780470755297.ch10

Udy, Andrew, Roberts, Jason A., Boots, Robert J. and Lipman, Jeffrey (2008). Dose adjustment and pharmacodynamic considerations for antibiotics in severe sepsis and septic shock. In Jordi Rello and Marcos I. Restrepo (Ed.), Sepsis: New strategies for management (pp. 97-102) London: Springer-Verlag. doi:10.1007/978-3-540-79001-3

Brown, Anthony F. and Lipman, Jeffrey (2008). Pre-hospital Care. In P. J. Papadakos and B. Lachmann (Ed.), Mechanical ventilation: clinical applications and pathophysiology (pp. 307-319) Philadelphia, United States: Saunders.

Roberts, J. A. and Lipman, J. (2007). Dose adjustment and pharmacokinetics of antibiotics in severe sepsis and septic shock. In Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez (Ed.), Infectious diseases in critical care 2nd ed. (pp. 122-146) Berlin, Germany; New York, U.S.A.: Springer. doi:10.1007/978-3-540-34406-3_12

Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. In Infectious diseases in critical care (pp. 147-158) Berlin, Germany: Springer. doi:10.1007/978-3-540-34406-3_13

Freebairn, R., Cohen, J. and Lipman, J. (2007). Prescription of antimicrobial agents in patients undergoing continuous renal replacement therapy. In Jordi Rello, Marin Kollef, Emili Diaz and Alejandro Rodriguez (Ed.), Infectious diseases in critical care 2nd ed. (pp. 147-159) Berlin & Heidelberg, Germany; New York, USA: Springer - Verlag.

Cohen, Jeremy and Lipman, Jeffrey (2006). Use and Abuse of antibiotics. In Nigel R. Webster and Helen F. Galley (Ed.), Anesthesia science (pp. 128-139) Malden, Mass.: Blackwell Pub.

Lipman, J. and Saadia, R. (1999). Acute Respiratory Distress Syndrome. In Stephen Westaby and John A. Odell (Ed.), Cardiothoracic Trauma (pp. 295-303) New York US: Oxford Univ. Press.

Hon, H. and Lipman, J. (1999). Tetanus - Prevention and management. In Webb, A. R., Shapiro, M. J., Singer, M. and Suter, P. M. (Ed.), Oxford Textbook of Critical Care (pp. 512-514) Oxford UK: Oxford Univ. Press.

Hopley, M. and Lipman, J. (1999). Tetanus - Pathophysiology. In Webb, A. R., Shapiro, M. J., Singer, M. and Suter, P. M. (Ed.), Oxford Textbook of Critical Care (pp. 510-512) Oxford UK: Oxford University press.

Yadav, Rajbharan, Bergen, Phillip J., Rogers, Kate E., Kirkpatrick, Carl M. J., Wallis, Steven C., Huang, Yuling, Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2020) Meropenem-tobramycin combination regimens combat carbapenem-resistant Pseudomonas aeruginosa in the hollow-fiber infection model simulating augmented renal clearance in critically ill patients. Antimicrobial Agents and Chemotherapy, 64 1: . doi:10.1128/aac.01679-19

Lonsdale, Dagan O. and Lipman, Jeffrey (2019) Antimicrobial resistance: we must pursue a collaborative, global approach and use a “one health” approach. Antibiotics, 8 4: . doi:10.3390/antibiotics8040237

Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019) Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 6: 741-749. doi:10.1016/j.ijantimicag.2019.08.024

Holley, Anthony D., Reade, Michael C., Lipman, Jeffrey, Delaney, Anthony, Udy, Andrew, Lee, Richard, Litton, Edward, Cheung, Winston, Turner, Andrew, Garside, Tessa, Macken, Lewis, Reddi, Benjamin, Kol, Mark, Kazemi, Alex, Shah, Asim, Townsend, Shane and Cohen, Jeremy (2019) Survey of critical care practice in Australian and New Zealand burn referral centres. Critical Care and Resuscitation, 21 4: 303-304.

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019) A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, . doi:10.1007/s00216-019-02184-4

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019) Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, . doi:10.1515/cclm-2019-0780

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019) Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 3: 1-4. doi:10.1159/000502474

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019) A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, . doi:10.1128/aac.01655-19

Ho, Kwok M., Rogers, Frederick B. and Lipman, Jeffrey (2019) The authors reply to: A multicenter trial of vena cava filters in severely injured patients. The New England Journal of Medicine, 381 15: 1496-1497. doi:10.1056/NEJMc1911302

Koulenti, Despoina, Xu, Elena, Yin Sum Mok, Isaac, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019) Lefamulin. Comment on: “Novel Antibiotics for Multidrug-Resistant Gram-Positive Microorganisms. Microorganisms, 2019, 7, 270”. Microorganisms, 7 10: 386. doi:10.3390/microorganisms7100386

Ballot, Daynia E., Bandini, Rosella, Nana, Trusha, Bosman, Noma, Thomas, Teena, Davies, Victor A., Cooper, Peter A., Mer, Mervyn and Lipman, Jeffrey (2019) A review of -multidrug-resistant Enterobacteriaceae in a neonatal unit in Johannesburg, South Africa. BMC Pediatrics, 19 1: 320. doi:10.1186/s12887-019-1709-y

Ho, Kwok M., Holley, Anthony and Lipman, Jeffrey (2019) Vena Cava filters in severely-injured patients: one size does not fit all. Anaesthesia Critical Care and Pain Medicine, 38 4: 305-307. doi:10.1016/j.accpm.2019.07.003

T.P. Wan, Winnie, Guerra Valero, Yarmarly, Choi, Gordon Y.S., Ordóñez Mejia, Jenny L., Wallis, Steven C., Joynt, Gavin M., Lipman, Jeffrey, Gomersall, Charles D. and Roberts, Jason A. (2019) In-vitro adsorption and sieving coefficient of ticarcillin-clavulanate during continuous haemofiltration. International Journal of Antimicrobial Agents, 54 2: 261-264. doi:10.1016/j.ijantimicag.2019.03.018

Laupland, Kevin B., Tabah, Alexis, Kelway, Charlotte and Lipman, Jeffrey (2019) Does intermittent pneumatic compression PREVENT deep vein thrombosis in the ICU?. Anaesthesia Critical Care and Pain Medicine, 38 4: 303-304. doi:10.1016/j.accpm.2019.05.006

Koulenti, Despoina, Xu, Elena, Mok, Isaac Yin Sum, Song, Andrew, Karageorgopoulos, Drosos E., Armaganidis, Apostolos, Lipman, Jeffrey and Tsiodras, Sotirios (2019) Novel antibiotics for multidrug-resistant gram-positive microorganisms. Microorganisms, 7 8: 270. doi:10.3390/microorganisms7080270

Dhaese, Sofie A.M., Thooft, Alexander D.J., Farkas, Andras, Lipman, Jeffrey, Verstraete, Alain G., Stove, Veronique, Roberts, Jason A. and De Waele, Jan J. (2019) Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: a prospective observational study. Journal of Critical Care, 52 75-79. doi:10.1016/j.jcrc.2019.04.013

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2019) Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction. Antimicrobial Agents and Chemotherapy, 63 10: . doi:10.1128/aac.01265-19

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth, Corcoran, Tomas, Misur, Philip, Edibam, Cyrus, Baker, Ross I., Chamberlain, Jenny, Forsdyke, Claire and Rogers, Frederick B. (2019) A multicenter trial of vena cava filters in severely injured patients. The New England Journal of Medicine, 381 4: 328-337. doi:10.1056/NEJMoa1806515

Sumi, Chandra Datta, Heffernan, Aaron J., Lipman, Jeffery, Roberts, Jason A. and Sime, Fekade B. (2019) What Antibiotic Exposures Are Required to Suppress the Emergence of Resistance for Gram‑Negative Bacteria? A Systematic Review. Clinical Pharmacokinetics, . doi:10.1007/s40262-019-00791-z

Denny, Kerina J., De Waele, Jan, Laupland, Kevin B., Harris, Patrick N. A. and Lipman, Jeffrey (2019) When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit. Clinical Microbiology and Infection, . doi:10.1016/j.cmi.2019.07.007

Weber, Nicholas, Jackson, Kathryn, McWhinney, Brett, Ungerer, Jacobus, Kennedy, Glen, Lipman, Jeffrey and Roberts, Jason A. (2019) Evaluation of pharmacokinetic/pharmacodynamic and clinical outcomes with 6-hourly empiric piperacillin-tazobactam dosing in hematological malignancy patients with febrile neutropenia. Journal of Infection and Chemotherapy, 25 7: 503-508. doi:10.1016/j.jiac.2019.02.014

Economou, Caleb J. P., Xie, Jiao, Comadira, Gregory, Richards, Brent, Tallott, Mandy, Wallis, Steven C., Ordoñez, Jenny, Lipman, Jeffrey and Roberts, Jason A. (2019) Population pharmacokinetics of ticarcillin in critically ill patients receiving extended daily diafiltration. International Journal of Antimicrobial Agents, 54 3: 351-355. doi:10.1016/j.ijantimicag.2019.06.027

Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019) Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 1. doi:10.1097/ftd.0000000000000658

Sime, Fekade B., Byrn, Catherine J., Parker, Suzanne, Stuart, Janine, Butler, Jenie, Starr, Therese, Pandey, Saurabh, Wallis, Steven C., Lipman, Jeffery and Roberts, Jason A. (2019) Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients. Critical Care, . doi:10.1186/s13054-019-2483-9

Roberts, Jason A., Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Sjövall, Fredrik (2019) Defining optimal dosing of ciprofloxacin in patients with septic shock. Journal of Antimicrobial Chemotherapy, 74 6: 1662-1669. doi:10.1093/jac/dkz069

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019) Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169 288-292. doi:10.1016/j.jpba.2019.03.018

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019) Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 7: 623-634. doi:10.1080/17512433.2019.1621161

De Backer, Daniel, Cecconi, Maurizio, Lipman, Jeffrey, Machado, Flavia, Myatra, Sheila Nainan, Ostermann, Marlies, Perner, Anders, Teboul, Jean-Louis, Vincent, Jean-Louis and Walley, Keith R. (2019) Challenges in the management of septic shock: a narrative review. Intensive Care Medicine, 45 4: 420-433. doi:10.1007/s00134-019-05544-x

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019) The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?. European Journal of Clinical Microbiology & Infectious Diseases, 38 4: 637-647. doi:10.1007/s10096-019-03486-2

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019) Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2). European Journal of Clinical Microbiology and Infectious Diseases, 38 4: 649-649. doi:10.1007/s10096-019-03518-x

Dhaese, Sofie A M, Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G, Roberts, Jason A and De Waele, Jan J (2019) Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 2: 432-441. doi:10.1093/jac/dky434

Koulenti, Despoina, Song, Andrew, Ellingboe, Aaron, Abdul-Aziz, Mohd Hafiz, Harris, Patrick, Gavey, Emile and Lipman, Jeffrey (2019) Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?. International Journal of Antimicrobial Agents, 53 3: 211-224. doi:10.1016/j.ijantimicag.2018.10.011

McCullough, James P.A., Lipman, Jeffrey and Presneill, Jeffrey J. (2018) The statistical curriculum within randomized controlled trials in critical illness. Critical Care Medicine, 46 12: 1985-1990. doi:10.1097/CCM.0000000000003380

Sakr, Yasser, Jaschinski, Ulrich, Wittebole, Xavier, Szakmany, Tamas, Lipman, Jeffrey, Namendys-Silva, Silvio A., Martin-Loeches, Ignacio, Leone, Marc, Lupu, Mary-Nicoleta and Vincent, Jean-Louis (2018) Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit. Open Forum Infectious Diseases, 5 12: ofy313. doi:10.1093/ofid/ofy313

Ballot, Daynia Elizabeth, Ramdin, Tanusha, White, Debbie Ann and Lipman, Jeffrey (2018) A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa. BMC Research Notes, 11 829. doi:10.1186/s13104-018-3946-9

Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2018) Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, . doi:10.1016/j.ijantimicag.2018.11.011

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2018) Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, . doi:10.1016/j.ijantimicag.2018.09.021

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018) A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminaemia receiving continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 52 4: 506-509. doi:10.1016/j.ijantimicag.2018.07.008

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018) Ex vivo characterization of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 10: . doi:10.1128/AAC.01306-18

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018) Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 10: AAC.01306-18. doi:10.1128/AAC.01306-18

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018) A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration. International Journal of Antimicrobial Agents, . doi:10.1016/j.ijantimicag.2018.07.008

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018) A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 1: 17. doi:10.1186/s40635-018-0180-7

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018) Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, . doi:10.1016/j.jpha.2018.07.003

Rhodes, Nathaniel J., Liu, Jiajun, Lipman, Jeffrey and Roberts, Jason A. (2018) The authors reply. Critical Care Medicine, 46 7: e725-e726. doi:10.1097/CCM.0000000000003164

Tsai, D., Stewart, P. C., Hewagama, S., Krishnaswamy, S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2018) Optimised dosing of vancomycin in critically ill Indigenous Australian patients with severe sepsis. Anaesthesia and Intensive Care, 46 4: 374-380.

Abdul-Aziz, Mohd H., Driver, Elicia, Lipman, Jeffrey and Roberts, Jason A. (2018) New paradigm for rapid achievement of appropriate therapy in special populations: coupling antibiotic dose optimisation rapid microbiological methods. Expert Opinion on Drug Metabolism and Toxicology, 14 7: 1-16. doi:10.1080/17425255.2018.1484452

Parker, Suzanne L, Saxena, Manoj, Gowardman, John, Lipman, Jeffrey, Myburgh, John and Roberts, Jason A. (2018) Population pharmacokinetics of intravenous paracetamol in critically ill patients with traumatic brain injury. Journal of Critical Care, 47 15-20. doi:10.1016/j.jcrc.2018.05.016

Dhanani, J. A., Barnett, A. G., Lipman, J. and Reade, M. C. (2018) Strategies to reduce inappropriate laboratory blood test orders in intensive care are effective and safe: a before-and-after quality improvement study. Anaesthesia and Intensive Care, 46 3: 313-320.

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018) Pharmacokinetics of intravenous posaconazole in critically ill patients. Antimicrobial Agents and Chemotherapy, 62 6: e00242-18. doi:10.1128/AAC.00242-18

Heffernan, A. J., Sime, F. B., Lipman, J. and Roberts, J. A. (2018) Individualising therapy to minimize bacterial multidrug resistance. Drugs, 78 6: 621-641. doi:10.1007/s40265-018-0891-9

Economou, Caleb J. P., Kielstein, Jan T., Czock, David, Xie, Jiao, Field, Jonathan, Richards, Brent, Tallot, Mandy, Visser, Adam, Koenig, Christina, Hafer, Carsten, Schmidt, Julius J., Lipman, Jeffrey and Roberts, Jason A. (2018) Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy. International Journal of Antimicrobial Agents, 52 2: 151-157. doi:10.1016/j.ijantimicag.2018.03.001

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018) Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 6: 1647-1650. doi:10.1093/jac/dky057

Yadav, Rajbharan, Rogers, Kate E., Bergen, Phillip J., Bulitta, Jürgen B., Kirkpatrick, Carl M. J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2018) Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens againstfor patients with altered pharmacokineticsthe hollow-fiber infection model and mechanism-based modeling. Antimicrobial Agents and Chemotherapy, 62 5: e00078-18. doi:10.1128/AAC.00078-18

Guerra Valero, Yarmarly C., Wallis, Steven C., Lipman, Jeffrey, Stove, Christophe, Roberts, Jason A. and Parker, Suzanne L. (2018) Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis, 10 6: 407-423. doi:10.4155/bio-2017-0269

Dahyot-Fizelier, Claire, Marchand, Sandrine and Lipman, Jeffrey (2018) Is augmented renal clearance the Holy Grail of antibiotic therapy failure in ventilator-acquired pneumonia?. Anaesthesia Critical Care & Pain Medicine, 37 1: 5-6. doi:10.1016/j.accpm.2017.12.003

Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul-Aziz, Mohd H., Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffery and Roberts, Jason A. (2018) Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis. Critical Care Medicine, 46 2: 236-243. doi:10.1097/CCM.0000000000002836

Naicker, Saiyuri, Guerra Valero, Yarmarly C., Ordenez Meija, Jenny L., Lipman, Jeffrey, Roberts, Jason A., Wallis, Steven C. and Parker, Suzanne L. (2018) A UHPLC–MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of Pharmaceutical and Biomedical Analysis, 148 324-333. doi:10.1016/j.jpba.2017.10.023

Bergen, Phillip J., Bulitta, Jürgen B., Sime, Fekade B., Lipman, Jeffrey, McGregor, Megan J., Millen, Nada, Paterson, David L., Kirkpatrick, Carl M. J., Roberts, Jason A. and Landersdorfer, Cornelia B. (2018) Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli. Diagnostic Microbiology and Infectious Disease, 91 1: 69-76. doi:10.1016/j.diagmicrobio.2017.12.019

De Waele, Jan J., Akova, Murat, Antonelli, Massimo, Canton, Rafael, Carlet, Jean, De Backer, Daniel, Dimopoulos, George, Garnacho-Montero, José, Kesecioglu, Jozef, Lipman, Jeffrey, Mer, Mervyn, Paiva, José-Artur, Poljak, Mario, Roberts, Jason A., Rodriguez Bano, Jesus, Timsit, Jean-François, Zahar, Jean-Ralph and Bassetti, Matteo (2017) Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. a position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Medicine, 44 2: 189-196. doi:10.1007/s00134-017-5036-1

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017) A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 12: e4030. doi:10.1002/bmc.4030

Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017) Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 1: 1-3. doi:10.1186/s13054-017-1871-2

Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017) Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 11: e00311-17. doi:10.1128/AAC.00311-17

de Prost, Nicholas, Lipman, Jeffrey and Mimoz, Olivier (2017) Therapeutic targets in necrotizing soft tissue infections. Intensive Care Medicine, 43 11: 1717-1719. doi:10.1007/s00134-017-4813-1

Udy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017) The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123 65-74. doi:10.1016/j.addr.2017.09.019

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017) Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 4: 439-454. doi:10.1007/s40262-017-0588-3

Sjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017) Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 1: 191-198. doi:10.1093/jac/dkx330

Xie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017) Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 8: e00345-17. doi:10.1128/AAC.00345-17

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017) Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 2: 227-231. doi:10.1016/j.ijantimicag.2017.03.018

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth and Corcoran, Tomas (2017) Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol. Bmj Open, 7 7: e016747. doi:10.1136/bmjopen-2017-016747

Badenes, Rafael, Oddo, Mauro, Suarez, Jose I., Antonelli, Massimo, Lipman, Jeffrey, Citerio, Giuseppe and Taccone, Fabio Silvio (2017) Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey. Critical Care, 21 1: 159. doi:10.1186/s13054-017-1748-4

Druery, Martha, Newcombe, Peter A., Cameron, Cate M. and Lipman, Jeffrey (2017) Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol. BMJ Open, 7 6: e017545. doi:10.1136/bmjopen-2017-017545

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017) An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 12: 911-924. doi:10.4155/bio-2017-0019

Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017) Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 6: 876-882. doi:10.1093/bja/aex026

Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017) Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 5: 589-594. doi:10.1016/j.ijantimicag.2017.01.009

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017) Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 5: e02642-16. doi:10.1128/AAC.02642-16

Poulakou, Garyfallia, Matthaiou, Dimitrios K., Bassetti, Matteo, Erdem, Hakan, Dimopoulos, George, Curcio, Daniel J., Carlet, Jean, Lipman, Jeffrey, Timsit, Jean‑François, Giamarellou, Helen, Arfaras-Melainis, Angelos and Rello, Jordi (2017) “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal. Intensive Care Medicine, 43 8: 1164-1166. doi:10.1007/s00134-017-4796-y

Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017) What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 6: 1-3. doi:10.1007/s00134-017-4789-x

Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017) Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 5: 624-630. doi:10.1016/j.ijantimicag.2016.12.022

Pretorius, Carel J., Reade, Michael C., Warnholtz, Chris, McWhinney, Brett, Phua, Meng Mei, Lipman, Jeffrey and Ungerer, Jacobus P. J. (2017) Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients. Clinica Chimica Acta, 466 72-77. doi:10.1016/j.cca.2017.01.012

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017) Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 3: e01276-16. doi:10.1128/AAC.01276-16

Williams, Julian M., Greenslade, Jaimi H., McKenzie, Juliet V., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2017) Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients with infection. Chest, 151 3: 586-596. doi:10.1016/j.chest.2016.10.057

Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017) Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 4: 395-402. doi:10.1016/j.ijantimicag.2016.12.014

Kollef, Marin H., Bassetti, Matteo, Francois, Bruno, Burnham, Jason, Dimopoulos, George, Garnacho-Montero, Jose, Lipman, Jeffrey, Luyt, Charles‑Edouard, Nicolau, David P., Postma, Maarten J., Torres, Antonio, Welte, Tobias and Wunderink, Richard G. (2017) The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship. Intensive Care Medicine, 43 9: 1-11. doi:10.1007/s00134-017-4682-7

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2017) Does furosemide increase oxidative stress in acute kidney injury?. Antioxidants & Redox Signaling, 26 5: 221-226. doi:10.1089/ars.2016.6845

Roberts, Jason A., Kumar, Anand and Lipman, Jeffrey (2017) Right dose, right now: customized drug dosing in the critically ill. Critical Care Medicine, 45 2: 331-336. doi:10.1097/CCM.0000000000002210

Sime, Fekade Bruck, Johnson, Adam, Whalley, Sarah, Santoyo-Castelazo, Anahi, Montgomery, A. Bruce, Walters, Kathie Ann, Lipman, Jeffrey, Hope, William W. and Roberts, Jason A. (2017) Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection model: experimental basis for combination therapy. Antimicrobial Agents and Chemotherapy, 61 1: e01763-16. doi:10.1128/AAC.01763-16

Udy, Andrew A., Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Starr, Therese, Dunlop, Rachel, Deans, Renae, Roberts, Jason A., Senthuran, Siva, Boots, Robert, Bisht, Kavita, Bulmer, Andrew C. and Lipman, Jeffrey (2017) Augmented renal clearance in traumatic brain injury: a single-center observational study of atrial natriuretic peptide, cardiac output, and creatinine clearance. Journal of Neurotrauma, 34 1: 137-144. doi:10.1089/neu.2015.4328

Roger, C., Wallis, S.C., Muller, L., Saissi, G., Lipman, J., Bruggemann, R.J., Lefrant, J.-Y. and Roberts, J.A. (2016) Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration. Clinical Pharmacokinetics, 56 9: 1-12. doi:10.1007/s40262-016-0495-z

Abdul-Aziz, Mohd. H., Lipman, Jeffrey and Roberts, Jason A. (2016) Antibiotic dosing for multidrug-resistant pathogen pneumonia. Current Opinion in Infectious Diseases, 30 2: 231-239. doi:10.1097/QCO.0000000000000348

Playford, E. Geoffrey, Lipman, Jeffrey, Jones, Michael, Lau, Anna F., Kabir, Masrura, Chen, Sharon C. -A., Marriott, Deborah J., Seppelt, Ian, Gottlieb, Thomas, Cheung, Winston, Iredell, Jonathan R., McBryde, Emma S. and Sorrell, Tania C. (2016) Problematic dichotomization of risk for Intensive Care Unit (ICU)-acquired invasive candidiasis: results using a risk-predictive model to categorize 3 levels of risk from a multicenter prospective cohort of Australian ICU patients. Clinical Infectious Diseases, 63 11: 1463-1469. doi:10.1093/cid/ciw610

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016) Pharmacokinetics of piperacillin in critically ill Australian Indigenous patients with severe sepsis. Antimicrobial Agents and Chemotherapy, 60 12: 7402-7406. doi:10.1128/AAC.01657-16

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016) Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 6: 748-752. doi:10.1016/j.ijantimicag.2016.09.021

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016) Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 11: 6550-6557. doi:10.1128/AAC.01088-16

Tsai, Danny, Stewart, Penelope, Goud, Rajendra, Gourley, Stephen, Hewagama, Saliya, Krishnaswamy, Sushena, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2016) Optimising meropenem dosing in critically ill Australian Indigenous patients with severe sepsis. International Journal of Antimicrobial Agents, 48 5: 542-546. doi:10.1016/j.ijantimicag.2016.08.015

Parker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016) Effect of time on recovery of plasma microsamples for the quantitative determination of vancomycin. Bioanalysis, 8 21: 2235-2242. doi:10.4155/bio-2016-0159

Zelenitsky, S. A., Lawson, C., Calic, D., Ariano, R. E., Roberts, J. A., Lipman, J. and Zhanel, G. G. (2016) Integrated pharmacokinetic-pharmacodynamic modelling to evaluate antimicrobial prophylaxis in abdominal surgery. Journal of Antimicrobial Chemotherapy, 71 10: 2902-2908. doi:10.1093/jac/dkw247

Tabah, Alexis, Lipman, Jeffrey and Roberts, Jason A. (2016) Are new gentamicin dosing guidelines suitable for achieving target concentrations in patients with sepsis and septic shock?. Anaesthesia, Critical Care and Pain Medicine, 35 5: 311-312. doi:10.1016/j.accpm.2016.08.002

Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016) Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35 231-239. doi:10.1016/j.jcrc.2016.06.022

Silbert, Benjamin I., Ho, Kwok M., Lipman, Jeffrey, Roberts, Jason A., Corcoran, Tomas B., Morgan, David J., Pavey, Warren, Mas, Emilie, Barden, Anne E. and Mori, Trevor A. (2016) Determinants of urinary output response to IV furosemide in acute kidney injury: a pharmacokinetic/pharmacodynamic study. Critical Care Medicine, 44 10: e923-e929. doi:10.1097/CCM.0000000000001823

Perner, Anders, Gordon, Anthony C., de Backer, Daniel, Dimopoulos, George, Russell, James A., Lipman, Jeffrey, Jensen, Jens‑Ulrik, Myburgh, John, Singer, Mervyn, Bellomo, Rinaldo and Walsh, Timothy (2016) Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy. Intensive Care Medicine, 42 12: 1-12. doi:10.1007/s00134-016-4577-z

Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016) Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 10: 1535-1545. doi:10.1007/s00134-015-4188-0

Roberts, Jason A., Abdul-Aziz, Mohd-Hafiz, Davis, Joshua S., Dulhunty, Joel M., Cotta, Menino O., Myburgh, John, Bellomo, Rinaldo and Lipman, Jeffrey (2016) Continuous versus intermittent β-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials. American Journal of Respiratory and Critical Care Medicine, 194 6: 681-691. doi:10.1164/rccm.201601-0024OC

Eley, Victoria, Callaway, Leonie, van Zundert, Andre, Lipman, Jeffrey and Gallois, Cindy (2016) Interpretation of care guidelines for obese women in labor: intergroup language and social identity. Journal of Language and Social Psychology, 36 4: 388-414. doi:10.1177/0261927X16668564

Eley, V. A., Van Zundert, A. A. J., Lipman, J. and Callaway, L. K. (2016) Anaesthetic management of obese parturients: what is the evidence supporting practice guidelines?. Anaesthesia and Intensive Care, 44 5: 552-559.

Eley, V. A., Callaway, L.K., Van Zundert, A. A. J., Lipman, J. and Gallois, C. (2016) Anaesthetists' experiences with the early labour epidural recommendation for obese parturients: a qualitative study. Anaesthesia and Intensive Care, 44 5: 620-626.

Labeau, Sonia O., Rello, Jordi, Dimopoulos, George, Lipman, Jeffrey, Sarikaya, Aklime, Ozturk, Candan, Vandijck, Dominique M., Vogelaers, Dirk, Vandewoude, Koenraad and Blot, Stijn I. (2016) The value of e-learning for the prevention of healthcare-associated infections. Infection Control and Hospital Epidemiology, 37 9: 1052-1059. doi:10.1017/ice.2016.107

Mcdonald, Craig, Cotta, Menino O., Little, Peter J., Mcwhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2016) Is high-dose beta-lactam therapy associated with excessive drug toxicity in critically ill patients?. Minerva Anestesiologica, 82 9: 957-965.

Dorofaeff, Tavey, Bandini, Rossella M., Lipman, Jeffrey, Ballot, Daynia E., Roberts, Jason A. and Parker, Suzanne L. (2016) Uncertainty in antibiotic dosing in critically ill neonate and pediatric patients: can microsampling provide the answers?. Clinical Therapeutics, 38 9: 1961-1975. doi:10.1016/j.clinthera.2016.07.093

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2016) Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling. Journal of Antimicrobial Chemotherapy, 71 9: 2509-2520. doi:10.1093/jac/dkw153

Harris P.N.A., McNamara J.F., Lye D.C., Davis J.S., Bernard L., Cheng A.C., Doi Y., Fowler V.G., Kaye K.S., Leibovici L., Lipman J., Llewelyn M.J., Munoz-Price S., Paul M., Peleg A.Y., Rodriguez-Bano J., Rogers B.A., Seifert H., Thamlikitkul V., Thwaites G., Tong S.Y.C., Turnidge J., Utili R., Webb S.A.R. and Paterson D.L. (2016) Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: A consensus definition. Clinical Microbiology and Infection, 23 8: 533-541. doi:10.1016/j.cmi.2016.10.023

Hanrahan, Timothy P., Lipman, Jeffrey and Roberts, Jason A. (2016) Antibiotic dosing in obesity: a BIG challenge. Critical Care, 20 240: 240. doi:10.1186/s13054-016-1426-y

Cristallini, Stefano, Hites, Maya, Kabtouri, Hakim, Roberts, Jason A., Beumier, Marjorie, Cotton, Frederic, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis, Creteur, Jacques and Taccone, Fabio Silvio (2016) New regimen for continuous infusion of vancomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 8: 4750-4756. doi:10.1128/AAC.00330-16

Roger, Claire, Wallis, Steven C., Muller, Laurent, Saissi, Gilbert, Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2016) Influence of renal replacement modalities on amikacin population pharmacokinetics in critically ill patients on continuous renal replacement therapy. Antimicrobial Agents and Chemotherapy, 60 8: 4901-4909. doi:10.1128/AAC.00828-16

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016) Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 8: 4577-4584. doi:10.1128/AAC.00531-16

Denny, Kerina Jane and Lipman, Jeffrey (2016) Bugs, genes, and the intensive care unit. Journal of Thoracic Disease, 8 8: E788-E790. doi:10.21037/jtd.2016.06.19

Ranganathan, Dwarakanathan, Naicker, Saiyuri, Wallis, Steven C., Lipman, Jeffrey, Ratanjee, Sharad K. and Roberts, Jason A. (2016) Stability of antibiotics for intraperitoneal administration in extraneal 7.5% icodextrin peritoneal dialysis bags (stab study). Peritoneal Dialysis International, 36 4: 421-426. doi:10.3747/pdi.2015.00062

Roberts, Darren M., Ranganathan, Dwarakanathan, Wallis, Steven C., Varghese, Julie M., Kark, Adrian, Lipman, Jeffrey and Roberts, Jason A. (2016) Pharmacokinetics of intraperitoneal cefalothin and cefazolin in patients being treated for peritoneal dialysis-associated peritonitis. Peritoneal Dialysis International, 36 4: 415-420. doi:10.3747/pdi.2015.00008

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016) Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 6: 436-438. doi:10.1016/j.ijantimicag.2016.02.017

Roger, Claire, Wallis, Steven C., Louart, Benjamin, Lefrant, Jean-Yves, Lipman, Jeffrey, Muller, Laurent and Roberts, Jason A. (2016) Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients. Journal of Antimicrobial Chemotherapy, 71 6: 1643-1650. doi:10.1093/jac/dkw043

Parker, Suzanne L., Guerra Valero, Yarmarly C., Roberts, Darren M., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2016) Determination of cefalothin and cefazolin in human plasma, urine and peritoneal dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical Chromatography, 30 6: 872-879. doi:10.1002/bmc.3622

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016) We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 1: . doi:10.1186/s13054-016-1348-8

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016) Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 6: 601-614. doi:10.1080/17425255.2016.1178238

Barbier, Francois, Lipman, Jeffrey and Bonten, Marc J. M. (2016) In 2035, will all bacteria be multidrug-resistant? No. Intensive Care Medicine, 42 12: 1-4. doi:10.1007/s00134-016-4348-x

Jager, Nynke G., van Hest, Reinier M., Lipman, Jeffrey, Taccone, Fabio S. and Roberts, Jason A. (2016) Therapeutic drug monitoring of anti-infective agents in critically ill patients. Expert Review of Clinical Pharmacology, 9 7: 961-979. doi:10.1586/17512433.2016.1172209

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016) The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 5: 667-678. doi:10.1517/14740338.2016.1164690

Alobaid, Abdulaziz S., Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio and Roberts, Jason A. (2016) Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review. International Journal of Antimicrobial Agents, 47 4: 259-268. doi:10.1016/j.ijantimicag.2016.01.009

Tong, Steven Y. C., Nelson, Jane, Paterson, David L., Fowler, Vance G., Jr., Howden, Benjamin P., Cheng, Allen C., Chatfield, Mark, Lipman, Jeffrey, Van Hal, Sebastian, O'Sullivan, Matthew, Robinson, James O., Yahav, Dafna, Lye, David and Davis, Joshua S. (2016) CAMERA2-combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial. Trials, 17 1: 170. doi:10.1186/s13063-016-1295-3

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016) What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 3: 696-702. doi:10.1093/jac/dkv412

Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016) SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 1: 103.1-103.8. doi:10.1186/s12879-016-1421-6

Dodds, Michelle M., Frazer, Callum D., Lipman, Jeffrey and Reade, Michael (2016) Use of neostigmine for acute colonic pseudo-obstruction in a patient receiving dexmedetomidine. Critical Care and Resuscitation, 18 1: 59-61.

Williams, Julian M., Greenslade, Jaimi H., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2016) Severity scores in emergency department patients with presumed infection: a prospective validation study. Critical Care Medicine, 44 3: 539-547. doi:10.1097/CCM.0000000000001427

Woodruff, Trent M., Wu, Mike C.-L., Morgan, Michael, Bain, Nathan T., Jeanes, Angela, Lipman, Jeffrey, Ting, Michael J., Boyd, Andrew W., Taylor, Stephen M. and Coulthard, Mark G. (2016) EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability. Shock, 45 2: 184-191. doi:10.1097/SHK.0000000000000494

Roger, C., Muller, L., Wallis, S. C., Louart, B., Saissi, G., Lipman, J., Lefrant, J. Y. and Roberts, J. A. (2016) Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 71 2: 464-470. doi:10.1093/jac/dkv349

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016) In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 2: 827-832. doi:10.1128/AAC.02461-15

Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016) Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 1: 206-214. doi:10.1128/AAC.01543-15

Williams, Julian M., Greenslade, Jaimi H., Dymond, Chelsea A., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffery (2016) Characteristics, treatment and outcomes for all emergency department patients fulfilling criteria for septic shock: a prospective observational study. European Journal of Emergency Medicine, 25 2: 1-104. doi:10.1097/MEJ.0000000000000419

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco, Gracia-Arnillas, Maria Pilar, Fernandez, Francisco, Feijoo, Neus, Bardolet, Neus, Rovira, Assumpta, Garro, Pau, Colon, Diana, Castillo, Carlos, Fernado, Juan, Lopez, Maria Jesus, Fernandez, Jose Luis, Arribas, Ana Maria, Teja, Jose Luis, Ots, Elsa, Montejo, Juan Carlos, Catalan, Marcedes, Prieto, Isidro, Gonzalo, Gloria, Galvan, Beatriz, Blasco, Miguel Ange, Meyer, Estibaliz, Nogal, Frutos Del, Vidaur, Loreto, Sebastian, Rosa, Garde, Pila Marco, Velasco, Maria del Mar Martin, Crespo, Rafael Zaragoza, Esperatti, Mariano, Torres, Antoni, Baldesi, Olivier, Dupont, Herve, Mahjoub, Yazine, Lasocki, Sigismond, Constantin, Jean Michel, Payen, Jean Francois, Albanese, Jacques, Malledant, Yannick, Pottecher, Julien, Lefrant, Jean-Yves, Jaber,Samir, Joannes-Boyau, Olivier, Orban,Christophe, Ostermann, Marlies, McKenzie, Catherine, Berry, Willaim, Smith, John, Lei, Katie, Rubulotta, Francesca, Gordon, Anthony, Brett, Stephen, Stotz, Martin, Templeton, Maie, Ebm, Claudia, Moran, Carl, Pettila, Ville, Xristodoulou, Aglaia, Theodorou, Vassiliki, Kouliatsis, Georgios, Sertaridou, Eleni, Anthopoulos, Georgios, Choutas, George, Rantis, Thanos, Karatzas, Stylianos, Balla, Margarita, Papanikolaou, Metaxia, Myrianthefs, Pavlos, Gavala, Alexandra, Fildisis, Georgios, Koutsoukou, Antonia, Kyriakopoulou, Magdalini, Petrochilou, Kalomoira, Kompoti, Maria, Michalia, Martha, Clouva-Molyvdas, Fillis-Maria, Gkiokas, Georgios, Nikolakopoulos, Fotios, Psychogiou, Vasiliki, Malliotakis, Polychronis, Akoumianaki, Evangelia, Lilitsis, Emmanouil, Koulouras, Vassilios, Nakos, George, Kalogirou, Mihalis, Komnos, Apostolos, Zafeiridis, Tilemachos, Chaintoutis, Christos, Arvaniti, Kostoula, Matamis, Dimitrios, Kydona, Christina, Gritsi-Gerogianni, Nikoleta, Giasnetsova, Tatiana, Giannakou, Maria, Soultati, Ioanna, Chytas, Ilias, Antoniadou, Eleni, Antipa, Elli, Lathyris, Dimitrios, Koukoubani,Triantafyllia, Paraforou, Theoniki, Spiropoulou, Kyriaki, Bekos, Vasileios, Spring, Anna, Kalatzi, Theodora, Nikolaou, Hara, Laskou, Maria, Strouvalis, Ioannis, Aloizos, Stavros, Kapogiannis, Spyridon, Soldatou, Ourania, Adembri, Chiara, Villa, Gianluca, Giarratano, Antonio, Raineri, Santi Maurizio, Cortegiani, Andrea, Montalto, Francesca, Strano, Maria Teresa, Ranieri, V. Marco, Sandroni, Claudio, De Pascale, Gennaro, Molin, Alexandre, Pelosi, Paolo, Montagnani, Luca, Urbino, Rosario, Mastromauro, Ilaria, De Rosa, Francesco G., Cardoso, Teresa, Afonso, Susana, Goncalves-Pereira, Joao, Baptista, Joao Pedro and Ozveren, Arife (2016) Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DA. Journal of Antimicrobial Chemotherapy, 71 1: 196-207. doi:10.1093/jac/dkv288

Saxena, Manoj K., Taylor, Colman, Billot, Laurent, Bompoint, Severine, Gowardman, John, Roberts, Jason A., Lipman, Jeffery and Myburgh, John (2015) The effect of paracetamol on core body temperature in acute traumatic brain injury: a randomised, controlled clinical trial. PloS One, 10 12: e0144740. doi:10.1371/journal.pone.0144740

Cotta, M. O., Roberts, J. A. and Lipman, J. (2015) Antibiotic dose optimization in critically ill patients / Optimización de la dosis de antibióticos en pacientes críticamente enfermos. Medicina Intensiva (English Edition), 39 9: 563-572. doi:10.1016/j.medine.2015.07.001

Huttner, Angela, Harbarth, Stephan, Hope, William W., Lipman, Jeffrey and Roberts, Jason A. (2015) Therapeutic drug monitoring of the beta-lactam antibiotics: what is the evidence and which patients should we be using it for?. Journal of Antimicrobial Chemotherapy, 70 12: 3178-3183. doi:10.1093/jac/dkv201

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A.R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K., Lipman, Jeffrey, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Boschert , Catherine, Fletcher, Jason, Smith, Julie, Nand, Kiran, Sara, Treena, Harney, Amy, Rodgers, Helen, Van Haren, Frank, Clarke, Sally, Durham, David, Hannan, Catherine, Matheson, Elisha, Schwartz, Kate, Thomas, Karen, Bone, Allison, Cattigan, Claire, Elderkin, Tania, Salerno, Tania, Cameron, Robert, Ellis, Katrina, Hatter, Sheridan, Davis, Joshua, Sanap, Milind, Soar, Natalie, Wood, Josette, Chan, Karen, Heffernan, Aaron, Lai, Nai An, Moss, Catherine, Sheehy, Kate, Duroux, Maree, Ratcliffe, Megan, Shone, Samantha, Warhurst, Timothy, Dunlop, Rachel, Roberts, Jason, Stuart, Janine, Udy, Andrew, Cooper, David, McAllister, Rick, Cheng, Andrew, Inskip, Deborah, Miller, Jennene, Reynolds, Claire, Rudham, Sam, Baker, Stuart, Hepburn, Kristy, Roberts, Brigit, Woods, Paul, Chatterjee, Indranil, Smith, Judy, Cullen, Martin, Kong, Jing, Nayyar, Vineet, Leung, Patricia, Whitehead, Christina, Gilder, Eileen, McCarthy, Lianne, McGuiness, Shay, Parke, Rachael, Benefield, Kirsten, Chen, Yan, McArthur, Colin, Newby, Lynette, Henderson, Seton, Mehrtens, Jan, Noble, Sascha, Chadwick, Lesley, Freebain, Ross, Hogan, Chantal, Kazemi, Alex, Rust, Laura, Song, Rima, Tilsley, Anna, Williams, Anthony, Andrews, Lynn, Dinsdale, Richard, Hunt, Anna, Hurford, Sally, Mackle, Diane, Ongley, Jessica, Young, Paul, Durning, John, Frengley, Robert, La Pine, Mary, McCracken, Geoff, Sharma, Swarna Baskar, Kollef, Marin, Turnidge, John and Paul, Sanjoy (2015) A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis. American Journal of Respiratory and Critical Care Medicine, 192 11: 1298-1305. doi:10.1164/rccm.201505-0857OC

Parker, Suzanne L., Lipman, Jeffrey, Dimopoulos, George, Roberts, Jason A. and Wallis, Steven C. (2015) A validated method for the quantification of fosfomycin on dried plasma spots by HPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 115 509-514. doi:10.1016/j.jpba.2015.07.013

Wong, Wai-Tat, Choi, Gordon, Gomersall, Charles D. and Lipman, Jeffrey (2015) To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: The eternal doubt. Current Opinion in Pharmacology, 24 68-78. doi:10.1016/j.coph.2015.07.003

Parker, Suzanne L., Frantzeskaki, Frantzeska, Wallis, Steven C., Diakaki, Chryssa, Giamarellou, Helen, Koulenti, Despoina, Karaiskos, Ilias, Lipman, Jeffrey, Dimopoulos, George and Roberts, Jason A. (2015) Population pharmacokinetics of fosfomycin in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 10: 6471-6476. doi:10.1128/AAC.01321-15

Parker, Suzanne L., Roberts, Jason A., Lipman, Jeffrey and Wallis, Steven C. (2015) Quantitative bioanalytical validation of fosfomycin in human whole blood with volumetric absorptive microsampling. Bioanalysis, 7 19: 2585-2595. doi:10.4155/bio.15.173

Tsai, Danny, Lipman, Jeffrey and Roberts, Jason A. (2015) Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Current Opinion in Critical Care, 21 5: 412-420. doi:10.1097/MCC.0000000000000229

Roberts, Jason A., Taccone, Fabio Silvio. and Lipman, Jeffrey. (2015) Understanding PK/PD. Intensive Care Medicine, 42 11: 1797-1800. doi:10.1007/s00134-015-4032-6

Parker, Suzanne L., Adnan, Syamhanin, Meija, Jenny L. Ordonez, Paterson, David L., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2015) An UHPLC-MS/MS method for the simultaneous determination of ampicillin and sulbactam in human plasma and urine. Bioanalysis, 7 18: 2311-2319. doi:10.4155/bio.15.143

Hanrahan, T. P., Kotapati, C., Roberts, M. J., Rowland, J., Lipman, J., Roberts, J. A. and Udy, A. (2015) Factors associated with vancomycin nephrotoxicity in the critically ill. Anaesthesia and Intensive Care, 43 5: 594-599.

Hanrahan, Timothy, Whitehouse, Tony, Lipman, Jeffrey and Roberts, Jason A. (2015) Vancomycin-associated nephrotoxicity: a meta-analysis of administration by continuous versus intermittent infusion. International Journal of Antimicrobial Agents, 46 3: 249-253. doi:10.1016/j.ijantimicag.2015.04.013

Tabah, Alexis, De Waele, Jan, Lipman, Jeffrey, Zahar, Jean Ralph, Cotta, Menino Osbert, Barton, Greg, Timsit, Jean-Francois and Roberts, Jason A. (2015) The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs. Journal of Antimicrobial Chemotherapy, 70 9: 2671-2677. doi:10.1093/jac/dkv165

Lipman, Jeffrey and Roberts, Jason (2015) Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 8: 1773-1774. doi:10.1097/CCM.0000000000001060

Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015) Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 8: 419-424. doi:10.5301/ijao.5000422

Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015) A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 8: 4689-4694. doi:10.1128/AAC.00409-15

Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015) Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 4: 367-375. doi:10.1016/j.ijantimicag.2015.06.016

Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A., Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015) Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 46 1: 39-44. doi:10.1016/j.ijantimicag.2015.02.014

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015) Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 1: 121-124. doi:10.1016/j.ijantimicag.2015.02.017

Brink, A. J., Richards, G. A., Lautenbach, E. E. G., Rapeport, N., Schillack, V., van Niekerk, L., Lipman, J. and Roberts, J. A. (2015) Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis. International Journal of Antimicrobial Agents, 45 6: 647-651. doi:10.1016/j.ijantimicag.2015.01.015

Finfer, Simon, Chittock, Dean, Li, Yang, Foster, Denise, Dhingra, Vinay, Bellomo, Rinaldo, Cook, Deborah, Dodek, Peter, Hebert, Paul, Henderson, William, Heyland, Daren, Higgins, Alisa, McArthur, Colin, Mitchell, Imogen, Myburgh, John, Robinson, Bruce, Ronco, Juan, Blair, Deborah, McArthur, Colin, Mitchell, Imogen, Norton, Robyn, Potter, Julie, Chittock, Dean, Dhingra, Vinay, Foster, Denise, Cook, Deborah, Dodek, Peter, Hebert, Paul, Henderson, William, Heyland, Daren, McDonald, Ellen, Ronco, Juan, Peto, Richard, Sandercock, Peter, Sprung, Charles, Young, J. Duncan, Li, Yang, Li, Qiang, Bompoint, Severine, Billot, Laurent, Li, Yang, Crampton, Leonie, Darcy, Fotios, Jayne, Kathy, Kumarasinghe, Viraji, Little, Lorraine, McEvoy, Suzanne, MacMahon, Stephen, Pandey, Sameer, Ryan, Suzanne, Shukla, Ravi, Vijayan, Bala, Robinson, Bruce, Atherton, Susan, Bell, Jeanette, Hadfield, Louise, Hourigan, Craig, McArthur, Colin, Newby, Lynette, Simmonds, Catherine, Buhr, Heidi, Eccleston, Michelle, McGuinness, Shay, Parke, Rachael, Bates, Samantha, Goldsmith, Donna, Mercer, Inga, O’Sullivan, Kim, Gazzard, Robert, Hill, Dianne, Tauschke, Christine, Ghelani, Dhawal, Nand, Kiran, Reece, Graham, Sara, Treena, Elliott, Suzanne, Ernest, David, Hamilton, Angela, Ashley, Rebecca, Bailey, Andrew, Crowfoot, Elise, Gissane, Jelena, Mitchell, Imogen, Ranse, Jamie, Whiting, Joy, Douglas, Kristina, Milliss, David, Tan, Jeff, Wong, Helen, Blythe, David, Palermo, Annemarie, Hardie, Miranda, Harrigan, Peter, McFadyen, Brett, Micallef, Sharon, Parr, Michael, Boase, Anna, Tai, Judi, Williams, Anthony, Cole, Louise, Seppelt, Ian, Weisbrodt, Leonie, Whereat, Sarah, Flanagan, Annette, Liang, Janet, Bass, Frances, Campbell, Michelle, Hammond, Naomi, Nicholson, Lisa, Shehabi, Yahya, Foote, Jonathan, Peake, Sandra, Williams, Patricia, Deans, Renae, Fourie, Cheryl, Lassig-Smith, Melissa, Lipman, Jeffrey, Stuart, Janine, Bell, Anthony, Field, Tanya, McAllister, Richard, Marsden, Kathryn, Turner, Andrew, Ankers, Susan, Bird, Simon, Finfer, Simon, Lee, Richard, O’Connor, Anne, Potter, Julie, Ramakrishnan, Naresh, Raper, Ray, Myburgh, John, Dhiacou, Vanessa, Girling, Kathryn, Jovanovska, Alina, Groves, Nicole, Holmes, Jenny, Santamaria, John, Smith, Roger, Baker, Stuart, Roberts, Brigit, Andrews, Lynne, Dinsdale, Richard, Fenton, Rosemary, Mackle, Diane, Mortimer, Sarah, French, Craig, Little, Lorraine, Raunow, Heike, Gales, Michelle, Hill, Francisco, Rachakonda, Sundaram, Rogan, Darren, Allsop, Christine, Higgins, Alisa, Varma, Dinesh, Champagne, Kevin, Doig, Christopher, Knox, Linda, Taylor, Pauline, Wilson, Crystal, Drover, John, Hammond, Sharlene, Mann, Elizabeth, Myers, Monica, Robinson, Amber, Harvey, Johanne, Skrobik, Yoanna, Baumgartner, Anita, Meade, Laurie, Vlahakis, Nicholas, Ethier, Cheryl, Kramer-Kile, Marnie, Mehta, Sangeeta, Gaudert, Claude, Kanji, Salmaan, McArdle, Tracy, Watpool, Irene, Clark, France, Cook, Deborah, McDonald, Ellen, Tkaczyk, Andrea, Marshall, John, Morrissey, Jeanna, Smith, Orla, Porretta, Kerri, Wen, Victoria, Ashley, Betty Jean, Dodek, Peter, Mans, Sheilagh, Bojilov, Boris, Code, Karen, Fowler, Robert, Marinoff, Nicole, Chu, Leslie, Granton, John, McGrath-Chong, Margaret, Steinberg, Marilyn, Ferguson, Niall, Go, Stephanie, Matte, Andrea, Rosenberg, Jonathan, Stevenson, James, Jacka, Michael, Sonnema, Leeca, Autio, Roger, Brevner, Angela, Chittock, Dean, Davies, Dara, Ganz, Pia, Gardner, Maureen, Logie, Susan, Smith, Laurie, Atkins, Leslie, Auld, Fiona, Stewart, Marni and Wood, Gordon (2015) Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. Intensive Care Medicine, 41 6: 1037-1047. doi:10.1007/s00134-015-3757-6

De Waele, J. J., Lipman, J., Akova, M., Bassetti, M. , Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P. , Rello, J. , Rhodes, A. , Udy, A. A. , Starr, T. , Wallis, S. C. and Roberts, J. A. (2015) Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 41 5: 969-969. doi:10.1007/s00134-015-3772-7

Hanrahan, Timothy P., Harlow, Georgina, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2015) Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply. Critical Care Medicine, 43 5: E154-E155. doi:10.1097/CCM.0000000000000952

Jamal, Janattul-Ain, Mueller, Bruce A., Choi, Gordon Y. S., Lipman, Jeffrey and Roberts, Jason A. (2015) How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?. Diagnostic Microbiology and Infectious Disease, 82 1: 92-103. doi:10.1016/j.diagmicrobio.2015.01.013

Joynt, Gavin M., Lipman, Jeffrey, Hartog, Christiane, Guidet, Bertrand, Paruk, Fathima, Feldman, Charles, Kissoon, Niranjan and Sprung, Charles L. (2015) The Durban World Congress Ethics Round Table IV: Health care professional end-of-life decision making. Journal of Critical Care, 30 2: 224-230. doi:10.1016/j.jcrc.2014.10.011

Lau, Anna F, Kabir, Masrura, Chen, Sharon C-A, Playford, E. Geoffrey, Marriott, Deborah J, Jones, Michael, Lipman, Jeffrey, McBryde, Emma, Gottlieb, Thomas, Cheung, Winston, Seppelt, Ian, Iredell, Jonathan and Sorrella, Tania C (2015) Candida colonization as a risk marker for invasive candidiasis in mixed medical-surgical intensive care units: Development and evaluation of a simple, standard protocol. Journal of Clinical Microbiology, 53 4: 1324-1330. doi:10.1128/JCM.03239-14

Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015) A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 84: . doi:10.1186/s13054-015-0818-8

Paratz, Jennifer D., Lipman, Jeffrey and Boots, Robert J. (2015) Serum markers of sepsis in burn patients: it takes more to convince! Reply. Critical Care Medicine, 43 3: E101-E101. doi:10.1097/CCM.0000000000000868

Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015) Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 3: 1411-1417. doi:10.1128/AAC.04001-14

Sakr, Yasser, Moreira, Cora L., Rhodes, Andrew, Ferguson, Niall D., Kleinpell, Ruth, Pickkers, Peter, Kuiper, Michael A., Lipman, Jeffrey, Vincent, Jean-Louis and Extended Prevalence of Infection in Intensive Care Study Investigators (2015) The impact of hospital and ICU organizational factors on outcome in critically ill patients: results from the Extended Prevalence of Infection in Intensive Care Study. Critical Care Medicine, 43 3: 519-526. doi:10.1097/CCM.0000000000000754

Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015) A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105 39-45. doi:10.1016/j.jpba.2014.11.042

Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015) Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 33: 1-7. doi:10.1186/s13054-015-0758-3

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015) Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 2: 192-195. doi:10.1016/j.ijantimicag.2014.08.013

Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015) Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 2: 528-533. doi:10.1093/jac/dku413

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015) Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 1: 136-153. doi:10.1055/s-0034-1398490

Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015) Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 28: 1-9. doi:10.1186/s13054-015-0750-y

Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015) Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 1: 24.1-24.8. doi:10.1186/s13063-014-0541-9

O'Callaghan D., Holley A. and Lipman J. (2015) From the intensive care bed: we need to hear and listen. Intensive Care Medicine, 41 5: 921-922. doi:10.1007/s00134-014-3614-z

Vermeir, Julie, Holley, Anthony and Lipman, Jeffrey (2015) “Not out of the woods”—a wife’s perspective: bedside communication. Intensive Care Medicine, 42 3: 446-447. doi:10.1007/s00134-015-4035-3

Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015) Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 10: 739-742. doi:10.3109/23744235.2015.1021831

De Waele, J.J., Lipman, J., Carlier, M. and Roberts, J.A. (2015) Subtleties in practical application of prolonged infusion of β-lactam antibiotics. International Journal of Antimicrobial Agents, 45 5: 461-463. doi:10.1016/j.ijantimicag.2015.01.007

Ramanan, Mahesh, Lipman, Jeffrey, Shorr, Andrew and Shankar, Aparna (2015) A meta-analysis of ventriculostomy-associated cerebrospinal fluid infections. Bmc Infectious Diseases, 15 1: 3. doi:10.1186/s12879-014-0712-z

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015) Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 45 1: 41-45. doi:10.1016/j.ijantimicag.2014.09.009

Udy A.A., De Waele J.J. and Lipman J. (2015) Augmented renal clearance and therapeutic monitoring of β-lactams. International Journal of Antimicrobial Agents, 45 4: 331-333. doi:10.1016/j.ijantimicag.2014.12.020

Shekar, Kiran, Fraser, John F., Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C., Mullany, Daniel V., Lipman, Jeffrey and Roberts, Jason A. (2014) The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study. Critical Care, 18 6: 1-9. doi:10.1186/s13054-014-0565-2

Guidet, Bertrand, Hodgson, Eric, Feldman, Charles, Paruk, Fathima, Lipman, Jeffrey, Koh, Younsuck, Vincent, Jean Louis, Azoulay, Elie and Sprung, Charles L. (2014) The Durban World Congress Ethics Round Table Conference Report: II. Withholding or withdrawing of treatment in elderly patients admitted to the intensive care unit. Journal of Critical Care, 29 6: 896-901. doi:10.1016/j.jcrc.2014.08.004

Sprung, Charles L., Paruk, Fathima, Kissoon, Niranjan, Hartog, Christiane S., Lipman, Jeffrey, Du, Bin, Argent, Andrew, Hodgson, R. Eric, Guidet, Bertrand, Groeneveld, A. B. Johan and Feldman, Charles (2014) The Durban World Congress Ethics Round Table conference report: I. Differences between withholding and withdrawing life-sustaining treatments. Journal of Critical Care, 29 6: 890-895. doi:10.1016/j.jcrc.2014.06.022

Paruk, Fathima, Kissoon, Niranjan, Hartog, Christiane S., Feldman, Charles, Hodgson, Eric R., Lipman, Jeffrey, Guidet, Bertrand, Du, Bin, Argent, Andrew and Sprung, Charles L. (2014) The Durban World Congress Ethics Round Table Conference Report: III. Withdrawing Mechanical ventilation-the approach should be individualized. Journal of Critical Care, 29 6: 902-907. doi:10.1016/j.jcrc.2014.05.022

De Waele, J., Carlier, M., Hoste, E., Depuydt, P., Decruyenaere, J., Wallis, S. C., Lipman, J. and Roberts, J. A. (2014) Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis. Minerva Anestesiologica, 80 12: 1302-1309.

Hanrahan, Timothy P., Harlow, Georgina, Hutchinson, James, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2014) Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis. Critical Care Medicine, 42 12: 2527-2536. doi:10.1097/CCM.0000000000000514

Udy, Andrew A., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2014) Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds. Critical Care, 18 657: 1-9. doi:10.1186/s13054-014-0657-z

Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014) How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 288: 1-11. doi:10.1186/1471-2334-14-288

Tsai, Danny, Jamal, Janattul-Ain, Davis, Joshua S., Lipman, Jeffrey and Roberts, Jason A. (2014) Interethnic differences in pharmacokinetics of antibacterials. Clinical Pharmacokinetics, 54 3: 243-260. doi:10.1007/s40262-014-0209-3

Talekar, C. R., Udy, A. A., Boots, R. J., Lipman, J. and Cook, D. (2014) Tracheal cuff pressure monitoring in the ICU: a literature review and survey of current practice in Queensland. Anaesthesia and intensive care, 42 6: 761-770.

Blot, Stijn I., Pea, Federico and Lipman, Jeffrey (2014) The effect of pathophysiology on pharmacokinetics in the critically ill patient - concepts appraised by the example of antimicrobial agents. Advanced Drug Delivery Reviews, 77 3-11. doi:10.1016/j.addr.2014.07.006

Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014) Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 10: 2797-2803. doi:10.1093/jac/dku195

Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014) Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 10: 1380-1384. doi:10.1177/1060028014540610

Hanberger, Hakan, Antonelli, Massimo, Holmbom, Martin, Lipman, Jeffrey, Pickkers, Peter, Leone, Marc, Rello, Jordi, Sakr, Yasser, Walther, Sten M., Vanhems, Philippe, Vincent, Jean-Louis, for the EPIC II Group of Investigators and Koulenti, D. (2014) Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels. BMC Infectious Diseases, 14 513: . doi:10.1186/1471-2334-14-513

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014) Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 6: 907-908. doi:10.1093/cid/ciu403

Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014) Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 5: 409-415. doi:10.1016/j.ijantimicag.2014.07.001

Udy, Andrew A., Baptista, Joao P., Lim, Noelle L., Joynt, Gavin M., Jarrett, Paul, Boots, Robert J. and Lipman, Jeffrey (2014) Augmented Renal Clearance in Critically Ill: Advantage or Threat Reply. Critical Care Medicine, 42 8: E602-E603. doi:10.1097/CCM.0000000000000465

Udy, Andrew A., Baptista, João P., Lim, Noelle L., Joynt, Gavin M., Jarrett, Paul, Boots, Robert J. and Lipman, Jeffrey (2014) The authors reply. Critical Care Medicine, 42 8: e602-e603. doi:10.1097/CCM.0000000000000465

De Waele, Jan J., Rello, Jordi, Anzueto, Antonio, Moreno, Rui, Lipman, Jeffrey, Sakr, Yasser, Pickkers, Peter, Leone, Marc, Ferguson, Andrew, Oud, Lavi and Vincent, Jean-Louis (2014) Infections and use of antibiotics in patients admitted for severe acute pancreatitis: Data from the epic II study. Surgical Infections, 15 4: 394-398. doi:10.1089/sur.2012.228

De Waele, Jan, Lipman, Jeffrey, Sakr, Yasser, Marshall, John C., Vanhems, Philippe, Barrera Groba, Casiano, Leone, Marc and Vincent, Jean-Louis (2014) Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome. BMC Infectious Diseases, 14 420: 1-17. doi:10.1186/1471-2334-14-420

Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014) The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 7: 1640-1650. doi:10.1097/CCM.0000000000000317

Paratz, Jennifer D., Stockton, Kellie, Paratz, Elizabeth D., Blot, Stijn, Muller, Michael, Lipman, Jeffrey and Boots, Robert J. (2014) Burn resuscitation - hourly urine output vs alternative endpoints: a systematic review. Shock, 42 4: 295-306. doi:10.1097/SHK.0000000000000204

Nunez-Nunez, Maria, Bellapart, Judith, O'Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P.J., Lipman, Jeffrey and Roberts, Jason A. (2014) Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International Journal of Antimicrobial Agents, 43 6: 571-572. doi:10.1016/j.ijantimicag.2014.03.001

Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014) Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 6: 572-573. doi:10.1016/j.ijantimicag.2014.03.001

Dulhunty, Joel M., Starr, Therese, Bellomo, Rinaldo and Lipman, Jeffrey (2014) Randomised controlled trials: the long hard climb to the summit - is there another way in the 21st century?. Critical Care and Resuscitation, 16 2: 87-89.

Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014) Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 3: 1-11. doi:10.1186/cc13874

Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014) Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 5: 1495-1502. doi:10.1093/jac/dku564

Blot,Stijn, Lipman, Jeffrey, Roberts, Darren M. and Roberts, Jason A (2014) The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?. Diagnostic Microbiology and Infectious Disease, 79 1: 77-84. doi:10.1016/j.diagmicrobio.2014.01.015

Vincent, Jean-Louis, Marshall, John C., Namendys-Silva, Silvo A., Francois, Bruno, Martin-Loeches, Ignacio, Lipman, Jeffrey, Reinhart, Konrad, Antonelli, Massimo, Pickkers, Peter, Njimi, Hassane, Jimenez, Edgar and Sakr, Yasser (2014) Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit. The Lancet Respiratory Medicine, 2 5: 380-386. doi:10.1016/S2213-2600(14)70061-X

Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014) An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 5: 1416-1423. doi:10.1093/jac/dkt523

Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014) DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 8: 1072-1083. doi:10.1093/cid/ciu027

Bellomo, Rinaldo, Cass, Alan, Cole, Louise, Finfer, Simon, Gallagher, Martin, Lee, Janne, Lo, Serigne, McArthur, Colin, McGuinness, Shay, Myburgh, John, Norton, Robyn, Scheinkestel, Carlos, The RENAL Study Investigators, Lipman, Jeffrey and Boots, Robert (2014) Calorie intake and patient outcomes in severe acute kidney injury: Findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial. Critical Care, 18 2: 1-11. doi:10.1186/cc13767

Thomas, Peter, Paratz, Jennifer and Lipman, Jeffrey (2014) Seated and semi-recumbent positioning of the ventilated intensive care patient - effect on gas exchange, respiratory mechanics and hemodynamics. Heart and Lung: Journal of Acute and Critical Care, 43 2: 105-111. doi:10.1016/j.hrtlng.2013.11.011

Varghese, Julie M., Jarrett, Paul, Boots, Robert J., Kirkpatrick, Carl M. J., Lipman, Jeffrey and Roberts, Jason A. (2014) Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 43 4: 343-348. doi:10.1016/j.ijantimicag.2014.01.009

Udy, Andrew A., Joynt, Gavin M. and Lipman, Jeffrey (2014) The authors reply. Critical Care Medicine, 42 10: e675-e676. doi:10.1097/CCM.0000000000000532

Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014) A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units. Nephrology, 19 8: 507-512. doi:10.1111/nep.12276

Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014) Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 5: 581-595. doi:10.1586/14787210.2014.902308

Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014) Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 6: 3533-3537. doi:10.1128/AAC.02340-14

Paratz, Jennifer D., Lipman, Jeffrey, Boots, Robert J., Muller, Michael J. and Paterson, David L. (2014) A new marker of sepsis post burn injury?. Critical Care Medicine, 42 9: 2029-2036. doi:10.1097/CCM.0000000000000400

Roberts, Jason A., Udy, Andrew A., Bulitta, Juergen B., Stuart, Janin, Jarrett, Paul, Starr, Therese, Lassig-Smith, Melissa, Roberts, Natasha A., Dunlop, Rachel, Hayashi, Yoshiro, Wallis, Steven C. and Lipman, Jeffrey (2014) Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 69 9: 2508-2516. doi:10.1093/jac/dku177

Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014) Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 5: 423-430. doi:10.1016/j.ijantimicag.2014.01.023

Gallagher M., Cass A., Bellomo R., Finfer S., Gattas D., Lee J., Lo S., McGuinness S., Myburgh J., Parke R., Rajbhandari D., Mitchell I., Taylor E., Whyte R., Raza A., Nand K., Sara T., Millis D., Wong H., Harrigan P., Hardie M., Whitaker D., Bhonagiri D., Micallef S., Ellem K., Lintott M., Cole L., Cuzner C., Weisbrodt L., Whereat S., Shehabi Y., Bass F., Edhouse P., Jenkins M., Finfer S., Bird S., O'Connor A., Totaro R., Honeysett L., Rajbhandari D., Myburgh J., Inskip D., Sidoli R., Nair P., Reynolds C., Banerjee A., Kong J., Skelly C., McGuinness S., Brown J., Gilder E., Parke R., McArthur C., Newby L., Simmonds C., Henderson S., Mehrtens J., Sugden D., Kalkoff M., McGregor K., Shaw C., Morgan J., Gregory K., Sutton J., Garrett P., Buckley A., McDonald S., Joyce C., Harward M., Sexton G., Perkins K., Lipman J., Dunlop R., Lassig-Smith M., Starr T., Flabouris A., O'Connor S., Rivett J., Turner A., McAllister R., Trubody V., Bellomo R., Eastwood G., Peck L., Fletcher J., Ihle B., Ho S., Micallef J., Murray L., Botha J., Allsop S., Vuat J., Cattigan C., Elderkin T., Walker C., Galt P., Gillies A., Harley N., Barge D., Caf T., Jordon A., Santamaria J., Holmes J., Smith R., Scheinkestel C., Donaldson H., Vallance S., French C., Bates S., Butler J., Breheny F., Palermo A., Dobb G., Chamberlain J., Lord P., Jun M., Yianni A. and D'Haeseleer S. (2014) Long-Term Survival and Dialysis Dependency Following Acute Kidney Injury in Intensive Care: Extended Follow-up of a Randomized Controlled Trial. PLoS Medicine, 11 2: 1-13. doi:10.1371/journal.pmed.1001601

De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C. and Roberts, J. A. (2014) Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 40 9: 1340-1351. doi:10.1007/s00134-014-3403-8

Escobar, Leslie, Andresen, Max, Downey, Patricio, Gai, Maria Nella, Regueira, Tomas, Borquez, Tamara, Lipman, Jeffrey and Roberts, Jason A. (2014) Population pharmacokinetics and dose simulation of vancomycin in critically ill patients during high-volume haemofiltration. International Journal of Antimicrobial Agents, 44 2: 163-167. doi:10.1016/j.ijantimicag.2014.03.009

Roberts, Jason A., Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander ., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely, Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula and Kuti, Joseph L. (2014) Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. The Lancet Infectious Diseases, 14 6: 498-509. doi:10.1016/S1473-3099(14)70036-2

Udy, Andrew A., Baptista, Joao P., Lim, Noelle L., Joynt, Gavin M., Jarrett, Paul, Wockner, Leesa, Boots, Robert J. and Lipman, Jeffrey (2014) Augmented renal clearance in the ICU: Results of a Multicenter observational study of renal function in critically ill patients with normal plasma Creatinine concentrations. Critical Care Medicine, 42 3: 520-527. doi:10.1097/CCM.0000000000000029

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013) Clinical implications of antibiotic pharmacokinetic principles in the critically ill. Intensive Care Medicine, 39 12: 2070-2082. doi:10.1007/s00134-013-3088-4

Paratz, Jennifer and Lipman, Jeffrey (2013) B-type natriuretic peptide: not just a heart throb. A & A Case Reports, 1 4: 59-61. doi:10.1097/ACC.0b013e31829737ab

Udy, Andrew A., Morton, Fraser J. A., Nguyen-Pham, Sallyanne, Jarrett, Paul, Lassig-Smith, Melissa, Stuart, Janine, Dunlop, Rachel, Starr, Therese, Boots, Robert J. and Lipman, Jeffrey (2013) A comparison of CKD-EPI estimated glomerular filtration rate and measured creatinine clearance in recently admitted critically ill patients with normal plasma creatinine concentrations. BMC Nephrology, 14 1: 250. doi:10.1186/1471-2369-14-250

Goh, H. M. Sharon, Beatson, Scott A., Totsika, Makrina, Moriel, Danilo G., Phan, Minh-Duy, Szubert, Jan, Runnegar, Naomi, Sidjabat, Hanna E., Paterson, David L., Nimmo, Graeme R., Lipman, Jeffrey and Schembri, Mark A. (2013) Molecular analysis of the Acinetobacter baumannii biofilm-associated protein. Applied and Environmental Microbiology, 79 21: 6535-6543. doi:10.1128/AEM.01402-13

Adnan, Syamhanin, Paterson, David L., Lipman, Jeffrey and Roberts, Jason A. (2013) Ampicillin/sulbactam: Its potential use in treating infections in critically ill patients. International Journal of Antimicrobial Agents, 42 5: 384-389. doi:10.1016/j.ijantimicag.2013.07.012

Moriel, Danilo G., Beatson, Scott A., Wurpel, Daniël J., Lipman, Jeffrey, Nimmo, Graeme R., Paterson, David L. and Schembri, Mark A. (2013) Identification of novel vaccine candidates against multidrug-resistant Acinetobacter baumannii. PLoS ONE, 8 10: e77631.1-e77631.9. doi:10.1371/journal.pone.0077631

Parker, Suzanne, Lipman, Jeffrey, Koulenti, Despoina, Dimopoulos, George and Roberts, Jason A. (2013) What is the relevance of fosfomycin pharmacokinetics in the treatment of serious infections in critically ill patients? A systematic review. International Journal of Antimicrobial Agents, 42 4: 289-293. doi:10.1016/j.ijantimicag.2013.05.018

Rello, Jordi and Lipman, Jeffrey (2013) Antibiotic prescription for respiratory tract infections in ventilated patients: where are we heading?. Intensive Care Medicine, 39 9: 1644-1646. doi:10.1007/s00134-013-2983-z

Putt, M. T., Udy, A. A., Jarrett, P., Martin, J., Hennig, S., Salmon, N., Lipman, J. and Roberts, J. A. (2013) Phenytoin loading doses in adult critical care patients: does current practice achieve adequate drug levels?. Anaesthesia and Intensive Care, 41 5: 602-609.

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Udy, Andrew A., Paul, Sanjoy K. and Lipman, Jeffrey (2013) A protocol for a multicentre randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis: the BLING II study. Critical Care and Resuscitation, 15 3: 179-185.

Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L. and Lipman, Jeffrey (2013) Reply to Soman et al. Clinical Infectious Diseases, 57 2: 323-324. doi:10.1093/cid/cit201

Pletz, Mathias W. and Lipman, Jeffrey (2013) Clinical measures for increased creatinine clearances and suboptimal antibiotic dosing. Intensive Care Medicine, 39 7: 1322-1324. doi:10.1007/s00134-013-2918-8

Adnan, Syamhanin, Li, Janice Xuanhui, Wallis, Steven C., Rudd, Michael, Jarrett, Paul, Paterson, David L., Lipman, Jeffrey, Udy, Andrew A. and Roberts, Jason A. (2013) Pharmacokinetics of meropenem and piperacillin in critically ill patients with indwelling surgical drains. International Journal of Antimicrobial Agents, 42 1: 90-93. doi:10.1016/j.ijantimicag.2013.02.023

Udy, Andrew A., Covajes, Cecilia, Taccone, Fabio Silvio, Jacobs, Frederique, Vincent, Jean-Louis, Lipman, Jeffrey and Roberts, Jason A. (2013) Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients?. International Journal of Antimicrobial Agents, 41 6: 564-568. doi:10.1016/j.ijantimicag.2013.01.018

Carlier, Mieke, Carrette, Sofie, Roberts, Jason A., Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C. and De Waele, Jan J. (2013) Meropenem and piperacillin/tazobactam prescribing in critically ill patients: Does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?. Critical Care, 17 3: R84.1-R84.9. doi:10.1186/cc12705

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2013) How should we dose antibiotics for pneumonia in the ICU?. Current Opinions in Infectious Diseases, 26 2: 189-195. doi:10.1097/QCO.0b013e32835d19e0

Hayashi, Yoshiro, Morisawa, Kenichiro, Klompas, Michael, Jones, Mark, Bandeshe, Hiran, Boots, Robert, Lipman, Jeffrey and Paterson, David L. (2013) Towards improved surveillance: the impact of ventilator-associated complications (VAC) on length of stay and antibiotic use in patients in intensive care units. Clinical Infectious Diseases, 56 5: 471-477. doi:10.1093/cid/cis926

Hayashi, Yoshiro, Lipman, Jeffrey, Udy, Andrew A., Ng, Mandy, McWhinney, Brett, Ungerer, Jacobus, Lust, Karin and Roberts, Jason A. (2013) β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia. International Journal of Antimicrobial Agents, 41 2: 162-166. doi:10.1016/j.ijantimicag.2012.10.002

Roberts, Jason and Lipman, Jeffrey (2013) Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance and decreased bacterial susceptibility. Critical Care Medicine, 41 2: 489-495. doi:10.1097/CCM.0b013e31826ab4c4

Ranganathan, Dwarakanathan, John, George T., Healy, Helen, Roberts, Matthew J., Fassett, Robert G., Lipman, Jeffrey, Kubler, Paul, Ungerer, Jacobus, McWhinney, Brett C., Lim, Aaron, Purvey, Megan, Reyaldeen, Reza and Roberts, Jason A. (2013) A protocol for the pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN): An open-label, randomised controlled trial. BMJ Open, 3 8: . doi:10.1136/bmjopen-2013-003511

Roberts, Jason, Pea, Federico and Lipman, Jeffrey (2013) The clinical relevance of plasma protein binding changes. Clinical Pharmacokinetics, 52 1: 1-8. doi:10.1007/s40262-012-0018-5

Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Haﬁz, Lipman, Jeffrey and Roberts, Jason A. (2013) Defining antibiotic dosing in lung infections. Clinical Pulmonary Medicine, 20 3: 121-128. doi:10.1097/CPM.0b013e31828fc646

Wong, Gloria, Briscoe, Scott, Adnan, Syamhanin, McWhinney, Brett, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A. (2013) Protein binding of β-lactam antibiotics in critically Ill patients: can we successfully predict unbound concentrations?. Antimicrobial Agents and Chemotherapy, 57 12: 6165-6170. doi:10.1128/AAC.00951-13

Carlier, Mieke, Noe, Michael, De Waele, Jan J., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2013) Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients. Journal of Antimicrobial Chemotherapy, 68 11: 2600-2608. doi:10.1093/jac/dkt240

Beumier, Marjorie, Roberts, Jason A., Kabtouri, Hakim, Hites, Maya, Cotton, Frederic, Wolff, Fleur, Lipman, Jeffrey, Jacobs, Frederique, Vincent, Jean-Louis and Taccone, Fabio Silvio (2013) A new regimen for continuous infusion of vancomycin during continuous renal replacement therapy. Journal of Antimicrobial Chemotherapy, 68 12: 2859-2865. doi:10.1093/jac/dkt261

Dulhunty, Joel M., Roberts, Jason A., Webb, Joshua S., Webb, Steve A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David and Lipman, Jeffrey (2013) Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicentre double-blind, randomised controlled trial.. Clinical Infectious Diseases, 56 2: 236-244. doi:10.1093/cid/cis856

Udy, Andrew A., Roberts, Jason A., Shorr, Andrew F., Boots, Robert J. and Lipman, Jeffrey (2013) Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients. Critical Care, 17 1: R35.1-R35.9. doi:10.1186/cc12544

Smith, Nicholas L., Freebairn, Ross C., Park, Michael A. J., Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2012) Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime. Critical Care and Resuscitation, 14 4: 312-315.

Myburgh, John A., Finfer, Simon, Bellomo, Rinaldo, Billot, Lauren, Cass, Alan, Gattas, David, Glass, Parisa, Lipman, Jeffrey, Liu, Bette, McArthur, Coline, McGuinness, Shay, Rajbhandari, Dorrilyn, Taylor, Colman B., Webb, Steven A. R., for the CHEST Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group and Reade, Michael (2012) Hydroxyethyl starch or saline for fluid resuscitation in intensive care. New England Journal of Medicine, 367 20: 1901-1911. doi:10.1056/NEJMoa1209759

Briscoe, Scott E., McWhinney, Brett C., Lipman, Jeffrey, Roberts, Jason A. and Ungerer, Jacobus P. J. (2012) A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 907 178-184. doi:10.1016/j.jchromb.2012.09.016

Jamal, Janattul-Ain, Economou, Caleb J. P., Lipman, Jeffrey and Roberts, Jason A. (2012) Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation. Current Opinion in Critical Care, 18 5: 460-471. doi:10.1097/MCC.0b013e32835685ad

Boots, R. J., Singh, S. J. and Lipman, J. (2012) The tyranny of distance: telemedicine for the critically ill in rural Australia. Anaesthesia and Intensive Care, 40 5: 871-874.

Ostrowski, J., Paterson, D. L., Lipman, J. and Udy, A. A. (2012) Blood culture collection in patients with acute kidney injury receiving renal replacement therapy: an observational study. Anaesthesia and Intensive Care, 40 5: 813-819.

Young, Paul, Hodgson, Carol, Dulhunty, Joel, Saxena, Manoj, Bailey, Michael, Bellomo, Rinaldo, Davies, Andrew, Finfer, Simon, Kruger, Peter, Lipman, Jeffrey, Myburgh, John, Peake, Sandra, Seppelt, Ian, Streat, Stephen, Tate, Rhiannon, Webb, Steven and The ANZICS Clinical Trials Group (2012) End points for phase II trials in intensive care: recommendations from the Australian and New Zealand Clinical Trials Group consensus panel meeting. Critical Care and Resuscitation, 14 3: 211-215.

Abdul-Aziz, Mohd H., Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey and Roberts, Jason A. (2012) Continuous beta-lactam infusion in critically ill patients: the clinical evidence. Annals of Intensive Care, 2 1: 37. doi:10.1186/2110-5820-2-37

Patel, Bhavik M., Paratz, Jennifer D., Mallet, Anthony, Lipman, Jeffrey, Rudd, Michael, Muller, Michael J., Paterson, David L. and Roberts, Jason A. (2012) Characteristics of bloodstream infections in burn patients: an 11-year retrospective study. Burns, 38 5: 685-690. doi:10.1016/j.burns.2011.12.018

Varghese, Julie M., Roberts, Jason A., Wallis, Steven C., Boots, Robert J., Healy, Helen, Fassett, Robert G., Lipman, Jeffrey and Ranganathan, Dwarakanathan (2012) Pharmacokinetics of intraperitoneal gentamicin in peritoneal dialysis patients with peritonitis (GIPD study). Clinical Journal of the American Society of Nephrology, 7 8: 1249-1256. doi:10.2215/CJN.12211211

Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012) Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 1: 35.1-35.11. doi:10.1186/2110-5820-2-35

Roberts, Jason, De Waele, Jan J., Dimopoulos, George, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven and Lipman, Jeffrey (2012) DALI: Defining Antibiotic Levels in Intensive care unit patients: a multi-centre point of prevalence study to determine whether contemporary antibiotic dosing for critically ill patients is therapeutic. BMC Infectious Diseases, 12 152.1-152.7. doi:10.1186/1471-2334-12-152

Udy, A. A., Altukroni, M., Jarrett, P., Roberts, J. A. and Lipman, J. (2012) A comparison of pulse contour wave analysis and ultrasonic cardiac output monitoring in the critically ill. Anaesthesia and Intensive Care, 40 4: 631-637.

Udy, Andrew A., Varghese, Julie M., Altukroni, Mahdi, Briscoe, Scott, McWhinney, Brett C., Ungerer, Jacobus P., Lipman, Jeffrey and Roberts, Jason A. (2012) Subtherapeutic Initial beta-Lactam Concentrations in Select Critically Ill Patients Association Between Augmented Renal Clearance and Low Trough Drug Concentrations. Chest, 142 1: 30-39. doi:10.1378/chest.11-1671

Roberts, Jason A. and Lipman, Jeffrey (2012) Closing the loop-a colistin clinical study to confirm dosing recommendations from PK/PD modeling. Clinical Infectious Diseases, 54 12: 1727-1729. doi:10.1093/cid/cis311

Dhanani, Jayesg, Roberts, Jason A. and Lipman, Jeffrey (2012) Antibiotic therapy of pneumonia in critical care. Current Respiratory Medicine Reviews, 8 3: 228-238. doi:10.2174/157339812800493232

Ginn, Andrew N., Wiklendt, Agnieszka M., Gidding, Heather F., George, Narelle, O'Driscoll, James S., Partridge, Sally R., O'Toole, Brian I., Perri, Rita A., Faoagali, Joan, Gallagher, John E., Lipman, Jeffrey and Iredell, Jonathan R. (2012) The ecology of antibiotic use in the ICU: Homogeneous prescribing of cefepime but not tazocin selects for antibiotic resistant infection. Plos One, 7 6: e38719.1-e38719.10. doi:10.1371/journal.pone.0038719

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012) beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 6: 489-496. doi:10.1111/j.1440-1681.2012.05715.x

Udy, Andrew A., Roberts, Jason A., De Waele, Jan J., Paterson, David L. and Lipman, Jeffrey (2012) What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance. International Journal of Antimicrobial Agents, 39 6: 455-457. doi:10.1016/j.ijantimicag.2012.02.010

Grewal, J. P., Singh, J. S. and Lipman, J. (2012) Methanol: don't forget the ethanol. Anaesthesia and Intensive Care, 40 3: 560-561.

Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012) Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 5: 1523-1528. doi:10.1097/CCM.0b013e318241e553

Holley, Anthony, Lukin, William, Paratz, Jennifer, Hawkins, Tracey, Boots, Robert and Lipman, Jeffrey (2012) Review article: Part two: Goal-directed resuscitation - Which goals? Perfusion targets. Emergency Medicine Australasia, 24 2: 127-135. doi:10.1111/j.1742-6723.2011.01515.x

Patel, Bhavik M., Paratz, Jennifer, See, Natalie C., Muller, Michael J., Rudd, Michael, Paterson, David, Briscoe, Scott E., Ungerer, Jacobus, McWhinney, Brett C., Lipman, Jeffrey and Roberts, Jason A. (2012) Therapeutic drug monitoring of beta-lactam antibiotics in burns patients-A one-year prospective study. Therapeutic Drug Monitoring, 34 2: 160-164. doi:10.1097/FTD.0b013e31824981a6

Myburgh, John, Li, Qiang, Heritier, Stephane, Dan, Arina, Glass, Parisa, McGuinness, S., Bellomo, R. , Fletcher, J., Poojara, L. , Ellem, K. , Mitchell, I. , Henderson, S. , Milliss, D. , Ihle, B., Haji, K., de Keulenaer, B., Cattigan, C. , Harrigan, P. , Parr, M., Presneill, J., Seppelt, I. , Liang, J., Duke, G., Shehabi, Y., Boots, R., Cooper, D., Finfer, S., Gattas, D., Myburgh, J., Santamaria, J., Browne, T., van Haren, F., Dinsdale, R., Venkatesh, B., McGain, F., Stachowski, E., Myburgh, J., Harland, J., Cass, A., Correa, M., Duke, G. , Glass, P. , Lee, J., Lipman, J., Liu, B. , McArthur, C. , Rajbhandari, D. , Taylor, C. , Webb, S. and Willenberg, L. (2012) Statistical analysis plan for the Crystalloid Versus Hydroxyethyl Starch Trial (CHEST). Critical Care and Resuscitation, 14 1: 44-52.

Roberts, Jason A., Joynt, Gavin M., Choi, Gordon Y.S., Gomersall, Charles D. and Lipman, Jeffrey (2012) How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics. International Journal of Antimicrobial Agents, 39 3: 187-192. doi:10.1016/j.ijantimicag.2011.11.002

Holley, Anthony, Lukin, William, Paratz, Jennifer, Hawkins, Tracey, Boots, Roberts and Lipman, Jeffrey (2012) Review article: Part one: Goal-directed resuscitation - Which goals? Haemodynamic targets. Emergency Medicine Australasia, 24 1: 14-22. doi:10.1111/j.1742-6723.2011.01516.x

Adnan, Syamhanin, Paterson, David, Lipman, Jeffrey, Kumar, Suresh, Li, Janice, Rudd, Michael J and Roberts, Jason (2012) Pharmacokinetics of beta-lactam antibiotics in patients with intra-abdominal disease: A structured review. Surgical Infections, 13 1: 9-17. doi:10.1089/sur.2011.046

Li, Janice, Udy, Andrew A., Kirkpatrick, Carl M.J., Lipman, Jeffrey and Roberts,Jason A. (2012) Improving vancomycin prescription in critical illness through a drug use evaluation process: a weight-based dosing intervention study. International Journal of Antimicrobial Agents, 39 1: 69-72. doi:10.1016/j.ijantimicag.2011.08.017

Abdul-Aziz, Mohd Hafiz, Staatz, C. E., Kirkpatrick, C. M. J., Lipman, J. and Roberts, J. A. (2012) Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics. Minerva Anestesiologica, 78 1: 94-104.

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012) Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 1: 1-10. doi:10.1016/j.ijantimicag.2011.07.013

Lonsdale, Dagan O., Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2012) Antibacterial therapeutic drug monitoring in cerebrospinal fluid: difficulty in achieving adequate drug concentrations. Journal of Neurosurgery, 118 2: 297-301. doi:10.3171/2012.10.JNS12883

Patel, Kashyap, Roberts, Jason A., Lipman, Jeffrey, Tett, Susan E., Deldot, Megan E. and Kirkpatrick, Carl M. (2011) Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration - using Monte Carlo Simulations to predict doses for specified pharmacodynamic targets. Antimicrobial Agents and Chemotherapy, 55 12: 5868-5873. doi:10.1128/AAC.00424-11

Boots, Robert James, Singh, Sunil, Terblanche, Morne, Widdicombe, Neil and Lipman, Jeffery (2011) Remote care by telemedicine in the ICU: Many models of care can be effective. Current Opinion in Critical Care, 17 6: 634-640. doi:10.1097/MCC.0b013e32834a789a

Hosein, Shaun, Udy, Andrew A. and Lipman, Jeffrey (2011) Physiological changes in the critically ill patient with sepsis. Current Pharmaceutical Biotechnology, 12 12: 1991-1995. doi:10.2174/138920111798808248

Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011) Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 11: 1431-1440. doi:10.1517/17425255.2011.615309

Lipman, J., Udy, A. and Roberts, Jason (2011) Do we understand the impact of altered physiology, consequent interventions and resultant clinical scenarios in the intensive care unit? The antibiotic story. Anaesthesia and Intensive Care, 39 6: 999-1000.

Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011) Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 11: 5238-5242. doi:10.1128/AAC.05033-11

Dulhunty, Joel, Boots, Robert J., Paratz, Jennifer D. and Lipman, Jeffrey (2011) Determining authorship in multicentre trials: A systematic review. Acta anaesthesiologica scandinavica, 55 9: 1037-1043. doi:10.1111/j.1399-6576.2011.02477.x

Hanberger, Hakan, Walther, Sten, Leone, Marc, Barie, Philip S., Rello, Jordi, Lipman, Jeffrey, Marshall, John C., Anzueto, Antonio, Sakr, Yasser, Pickkers, Peter, Felleiter, Peter, Engoren, Milo, Vincent, Jean-Louis and Epic II Group of Investigators (2011) Increased mortality associated with meticillin-resistant Staphylococcus aureus (MRSA) infection in the Intensive Care Unit: Results from the EPIC II study. International Journal of Antimicrobial Agents, 38 4: 331-335. doi:10.1016/j.ijantimicag.2011.05.013

Boots, Robert J., Lipman, Jeffrey, Lassig-Smith, Melissa, Stephens, DP, Thomas, J., Shehabi, Y., Bass, F., Anthony, A., Long, D., Seppelt, I.M., Weisbrodt, L., Erickson, S., Beca, J., Sherring, C., McGuiness, S., Parke, R., Stachowski, E.R., Boyd, R. and Howe, B. (2011) Experience with high frequency oscillation ventilation during the 2009 H1N1 influenza pandemic in Australia and New Zealand. Anaesthesia and Intensive Care, 39 5: 837-846.

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey (2011) Implications of augmented renal clearance in critically ill patients. Nature Reviews Nephrology, 7 9: 539-543. doi:10.1038/nrneph.2011.92

Martin, Jennifer H., Fay, Michael F., Udy, Andrew, Roberts, Jason, Kirkpatrick, Carl, Ungerer, Jacobus and Lipman, Jeffrey (2011) Pitfalls of using estimations of glomerular filtration rate in an intensive care population. Internal Medicine Journal, 41 7: 537-543. doi:10.1111/j.1445-5994.2009.02160.x

Baba, H., Nimmo, G. R., Allworth, A. M., Boots, R. J., Hayashi, Y., Lipman, J. and Paterson, D. L. (2011) The role of surveillance cultures in the prediction of susceptibility patterns of Gram-negative bacilli in the intensive care unit. European Journal of Clinical Microbiology and Infectious Diseases, 30 6: 739-744. doi:10.1007/s10096-010-1146-1

Roberts, Jason A., Taccone, Fabio Silvio, Udy, Andrew A., Vincent, Jean-Louis, Jacobs, Frederique and Lipman, Jeffrey (2011) Vancomycin Dosing in Critically Ill Patients: Robust Methods for Improved Continuous-Infusion Regimens. Antimicrobial Agents and Chemotherapy, 55 6: 2704-2709. doi:10.1128/AAC.01708-10

Baptista, Joao P., Udy, Andrew A., Sousa, Eduardo, Pimentel, Jorge, Wang, Lisa, Roberts, Jason A. and Lipman, Jeffrey (2011) A comparison of estimates of glomerular filtration in critically ill patients with augmented renal clearance. Critical Care, 15 3: 1-8. doi:10.1186/cc10262

Sutherland, Allison, Thomas, Mervyn, Brandon, Roslyn A., Brandon, Richard B., Lipman, Jeffrey, Tang, Benjamin, McLean, Anthony, Pascoe, Ranald, Price, Gareth, Nguyen, Thu, Stone, Glenn and Venter, Deon (2011) Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis. Critical Care, 15 3: 1-11. doi:10.1186/cc10274

Udy, Andrew, Boots, Robert J., Putt, Michael and Lipman, Jeffrey (2011) ARC - Augmented renal clearance. Current Pharmaceutical Biotechnology, 12 12: 2020-2029. doi:10.2174/138920111798808446

Myburgh, John, Bellomo, Rinaldo, Cass, Alan, Finfer, Simon, French, Julie, Gattas, David, Glass, Parisa, Lee, Joanne, Lipman, Jeffrey, Liu, Bette, McArthur, Colin, McGuinness, Shay, Rajbhandari, Dorrilyn, Taylor, Colman and Webb, Steve (2011) The Crystalloid versus Hydroxyethyl Starch Trial: Protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality. Intensive Care Medicine, 37 5: 816-823. doi:10.1007/s00134-010-2117-9

Higgins, A. M., Pettila, V., Harris, A. H., Bailey, M., Lipman, J., Seppelt, I. M. and Webb, S. A. (2011) The critical care costs of the Influenza A/H1N1 2009 epidemic in Australia and New Zealand. Anaesthesia and Intensive Care, 39 3: 384-391.

Ulldemolins, Marta, Roberts, Jason A., Lipman, Jeffrey and Rello, Jordi (2011) Antibiotic dosing in multiple organ dysfunction syndrome. Chest, 139 5: 1210-1220. doi:10.1378/chest.10-2371

Roberts, Jason A., Mehta, Ravindra L. and Lipman, Jeffrey (2011) Sustained low efficiency dialysis allows rational renal replacement therapy, but does it allow rational drug dosing?. Critical Care Medicine, 39 3: 602-603. doi:10.1097/CCM.0b013e31820e6a0d

Dulhunty, J. M., Paterson, D., Webb, S. A. R. and Lipman, J. (2011) Antimicrobial utilisation in 37 Australian and New Zealand intensive care units. Anaesthesia and Intensive Care, 39 2: 231-237.

Williams, Julian, Greenslade, Jaimi, Chu, Kevin, Brown, Anthony F., Paterson, David and Lipman, Jeffrey (2011) Prior statin use is not associated with improved outcome in emergency patients admitted with infection: A prospective observational study. Academic Emergency Medicine, 18 2: 127-134. doi:10.1111/j.1553-2712.2010.00976.x

Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011) Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 3.1-3.7. doi:10.1186/1471-2253-11-3

Roberts, Jason, Kirkpatrick, Carl M.J. and Lipman, Jeffrey (2011) Monte Carlo simulations: Maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients. Journal of Antimicrobial Chemotherapy, 66 2: 227-231. doi:10.1093/jac/dkq449

Ulldemolins, Marta, Roberts, Jason A., Rello, Jordi, Paterson, David L. and Lipman, Jeffrey (2011) The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clinical Pharmacokinetics, 50 2: 99-110. doi:10.2165/11539220-000000000-00000

Williams, Julian M., Greenslade, Jaimi H., McKenzie, Juliet V., Chu, Kevin H., Brown, Anthony F. T., Paterson, David and Lipman, Jeffrey (2011) A prospective registry of emergency department patients admitted with infection. BMC Infectious Diseases, 11 27-1-27-7. doi:10.1186/1471-2334-11-27

McGloughlin, Steven, Roberts, Jason A., O'Donoghue, Steven, Martin, Jennifer, Briscoe, Scott and Lipman, Jeffrey (2011) Ganciclovir pharmacokinetics and suggested dosing in continuous venovenous haemodiafiltration. International Journal of Antimicrobial Agents, 37 1: 90-92. doi:10.1016/j.ijantimicag.2010.10.003

Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy, Banks, Merrilyn, Dulhunty, Joel, Roberts, Jason A. and Lipman, Jeffrey (2011) Effect of intravenous GLutamine supplementation in Trauma patients receiving enteral nutrition study protocol (GLINT Study): A prospective, blinded, randomised, placebo-controlled clinical trial. BMJ Open, 1 2: 1-8. doi:10.1136/bmjopen-2011-000334

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2011) Antimicrobial Pharmacokinetic and Pharmacodynamic Issues in the Critically Ill with Severe Sepsis and Septic Shock. Critical Care Clinics, 27 1: 19-34. doi:10.1016/j.ccc.2010.09.006

Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011) The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 5.1-5.5. doi:10.1186/1471-2253-11-5

Udy, A, Boots, R, Senthuran, S, Stuart, J, Deans, R, Lassig-Smith, M and Lipman, J (2010) Augmented creatinine clearance in traumatic brain injury. Anesthesia And Analgesia, 111 6: 1505-1510. doi:10.1213/ANE.0b013e3181f7107d

Dhanani, Jayesh, Roberts, Jason A., Chew, Michelle, Lipman, Jeffrey, Boots, Robert J., Paterson, David L. and Fraser, John F. (2010) Antimicrobial chemotherapy and lung microdialysis: a review. International Journal of Antimicrobial Agents, 36 6: 491-500. doi:10.1016/j.ijantimicag.2010.08.013

Boots, Robert J., Udy, Andrew, Holley, Anthony and Lipman, Jeffrey (2010) Preventive strategies for ventilator associated pneumonia. Current Respiratory Medicine Reviews, 6 4: 238-252. doi:10.2174/157339810793563758

Boots, Robert J., Dulhunty, Joel M., Paratz, Jennifer and Lipman, Jeffrey (2010) Respiratory burns: A clinical review. Current Respiratory Medicine Reviews, 6 4: 285-291. doi:10.2174/157339810793563730

Choi, G, Gomersall, CD, Tian, Q, Joynt, GM, Li, AMMY and Lipman, J (2010) Principles of antibacterial dosing in continuous renal replacement therapy. Blood Purification, 30 3: 195-212. doi:10.1159/000321488

Douglas, A. E., Holley, A., Udy, A., Lipman, J., Gomersall, C. D., Joynt, G, Freebairn, R. C. and Boots, R. J. (2010) Can learning to sustain life be BASIC? Teaching for the initial management of the critically ill in Australia and New Zealand. Anaesthesia and Intensive Care, 38 6: 1043-1051.

Roberts, Jason, Boots, Robert J. and Lipman, Jeffrey (2010) Optimal antibiotic therapy in the management of the lung of the critically ill. Current Reviews in Respiratory Medicine, 6 4: 253-263. doi:10.2174/157339810793563749

Playford, EG, Lipman, J and Sorrell, TC (2010) Prophylaxis, empirical and preemptive treatment of invasive candidiasis. Current Opinion in Critical Care, 16 5: 470-474. doi:10.1097/MCC.0b013e32833e10e8

Roberts, Jason A., Ulldemolins, Marta, Roberts, Michael S., McWhinney, Brett, Ungerer, Jacobus, Paterson, David L. and Lipman, Jeffrey (2010) Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept. International Journal of Antimicrobial Agents, 36 4: 332-339. doi:10.1016/j.ijantimicag.2010.06.008

Clifford, Michaela E., Banks, Merrilyn D., Ross, Lynda J., Obersky, Natalie A., Forbes, Sharon A., Hegde, Rajeev and Lipman, Jeffrey (2010) A detailed feeding algorithm improves delivery of nutrition support in an intensive care unit. Critical Care and Resuscitation, 12 3: 149-155.

Roberts, Jason A., Field, Jonathan, Visser, Adam, Whitbread, Rosemary, Tallot, Mandy, Lipman, Jeffrey and Kirkpatrick, Carl M. J. (2010) Using population pharmacokinetics to determine Gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury. Antimicrobial Agents and Chemotherapy, 54 9: 3635-3640. doi:10.1128/AAC.00222-10

Dulhunty, Joel, Webb, Steven, Paterson, David, Bellomo, Rinaldo, Myburgh, John, Roberts, Jason and Lipman, Jeffrey (2010) A survey of antibiotic prescribing practices in Australian and New Zealand intensive care units. Critical Care and Resuscitation, 12 3: 162-170.

Hayashi, Yoshiro, Roberts, Jason A., Paterson, David L. and Lipman, Jeffrey (2010) Pharmacokinetic evaluation of piperacillin-tazobactam. Expert Opinion on Drug Metabolism and Toxicology, 6 8: 1017-1031. doi:10.1517/17425255.2010.506187

Varghese, Julie M., Roberts, Jason A. and Lipman, Jeffrey (2010) Pharmacokinetics and pharmacodynamics in critically ill patients. Current Opinion in Anesthesiology, 23 4: 472-478. doi:10.1097/ACO.0b013e328339ef0a

Ulldemolins, Marta, Roberts, Jason A., Wallis, Steven C., Rello, Jordi and Lipman, Jeffrey (2010) Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: Special emphasis on unbound pharmacokinetics. Journal of Antimicrobial Chemotherapy, 65 8: 1771-1778. doi:10.1093/jac/dkq184

Patil, Vikram, Dulhunty, Joel M., Udy, Andrew, Thomas, Peter, Kucharski, Geraldine and Lipman, Jeffrey (2010) Do burn patients cost more?: The intensive care unit costs of burn patients compared with controls matched for length of stay and acuity. Journal of Burn Care and Research, 31 4: 598-602. doi:10.1097/BCR.0b013e3181e4d6a4

Ulldemolins, Marta, Roberts, Jason A. and Lipman, Jeffrey (2010) Optimizing antibiotic use in the intensive care unit. Clinical Pulmonary Medicine, 17 4: 162-169. doi:10.1097/CPM.0b013e3181e47953

Bilgrami, I., Roberts, J. A., Wallis, S. C., Thomas, J., Davis, J., Fowler, S., Goldrick, P. B. and Lipman, J. (2010) Meropenem dosing in critically ill patients with sepsis receiving high-volume continuous venovenous hemofiltration. Antimicrobial Agents and Chemotherapy, 54 7: 2974-2978. doi:10.1128/AAC.01582-09

McWhinney, Brett C., Wallis, Steven C., Hillister, Tara, Roberts, Jason A., Lipman, Jeffrey and Ungerer, Jacobus P.J. (2010) Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 22: 2039-2043. doi:10.1016/j.jchromb.2010.05.027

Corona, A, Bertolini, G, Lipman, J, Wilson, AP and Singer, M (2010) Antibiotic use and impact on outcome from bacteraemic critical illness: The BActeraemia study in intensive care (BASIC). Journal of Antimicrobial Chemotherapy, 65 6: 1276-1285. doi:10.1093/jac/dkq088

Udy, Andrew A., Putt, Michael T., Shanmugathasan, Sulochana, Roberts, Jason A. and Lipman, Jeffrey (2010) Augmented renal clearance in the Intensive Care Unit: An illustrative case series. International Journal of Antimicrobial Agents, 35 6: 606-608. doi:10.1016/j.ijantimicag.2010.02.013

Roberts, Jason A., Ulldemolins, Marta and Lipman, Jeffrey (2010) Meropenem: Focus on its use in serious bacterial infections. Clinical Medicine Reviews in Therapeutics, 2 1-14. doi:10.4137/CMRT.S4598

Playford, E. Geoffrey, Lipman, Jeff and Sorrell, Tania C. (2010) Management of invasive candidiasis in the intensive care unit. Drugs, 70 7: 823-839. doi:10.2165/10898550-000000000-00000

Gowardman, J. R., Lipman, J. and Rickard, C. M. (2010) Assessment of peripheral arterial catheters as a source of sepsis in the critically ill: A narrative review. Journal of Hospital Infection, 75 1: 12-18. doi:10.1016/j.jhin.2010.01.005

Roberts, Jason A., Hope, William W. and Lipman, Jeffrey (2010) Therapeutic drug monitoring of beta-lactams for critically ill patients: Unwarranted or essential?. International Journal of Antimicrobial Agents, 35 5: 419-420. doi:10.1016/j.ijantimicag.2010.01.022

Doidge, Michelle, Allworth, Anthony M., Woods, Marion, Marshall, Penelope, Terry, Marshall, O'Brien, Kathryn, Goh, Hwee Mian, George, Narelle, Nimmo, Graeme R., Schembri, Mark A., Lipman, Jeffery and Paterson, David L. (2010) Control of an outbreak of carbapenem-resistant Acinetobacter baumannii in Australia after introduction of environmental cleaning with a commercial oxidizing disinfectant. Infection Control and Hospital Epidemiology, 31 4: 418-420. doi:10.1086/651312

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010) First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 2: 156-163. doi:10.1016/j.ijantimicag.2009.10.008

Udy, Andrew A., Roberts, Jason A., Boots, Robert J., Paterson, David L. and Lipman, Jeffrey (2010) Augmented renal clearance: Implications for antibacterial dosing in the critically Ill. Clinical Pharmacokinetics, 49 1: 1-16. doi:10.2165/11318140-000000000-00000

Playford, E. G., Lipman, J., Kabir, M., McBryde, E. S., Nimmo, Graeme R., Lau, A. and Sorrell, T. C. (2009) Assessment of clinical risk predictive rules for invasive candidiasis in a prospective multicentre cohort of ICU patients. Intensive Care Medicine, 35 12: 2141-2145. doi:10.1007/s00134-009-1619-9

McNeill, G, Holley, A and Lipman, J (2009) Emphysematous pyelonephritis: an unusual complication of blunt abdominal trauma. Critical Care and Resuscitation, 11 4: 269-271.

Ranganathan, Dwarakanathan, Varghese, Julie M., Fassett, Robert G., Lipman, Jeffrey, D'Intini, Vincent, Healy, Helen and Roberts, Jason A. (2009) Optimising intraperitoneal gentamicin dosing in peritoneal dialysis patients with peritonitis (GIPD) study. BMC Nephrology, 10 1: 1-6. doi:10.1186/1471-2369-10-42

Lipman, Jeffrey and Boots, Rob (2009) A new paradigm for treating infections: "go hard and go home". Critical Care and Resuscitation, 11 4: 276-281.

Vincent, Jean-Louis, Rello, Jordi, Marshall, John, Silva, Eliezer, Anzueto, Antonio, Martin, Claude D., Moreno, Rui, Lipman, Jeffrey, Gomersall, Charles, Sakr, Yasser and Reinhart, Konrad (2009) International Study of the Prevalence and Outcomes of Infection in Intensive Care Units. Journal of the American Medical Association, 302 21: 2323-2329. doi:10.1001/jama.2009.1754

Chatterjee, I., Dulhunty, J.M., Iredell, J., Gallagher, J.E., Sud, A., Woods, M. and Lipman, J. (2009) Predictors and outcome associated with an Enterococcus positive isolate during intensive care unit admission. Anaesthesia and Intensive Care, 37 6: 976-982.

Li, A. M. M. Y., Gomersall, C. D., Choi, G., Tian, Q., Joynt, G. M. and Lipman, J. (2009) A systematic review of antibiotic dosing regimens for septic patients receiving continuous renal replacement therapy: do current studies supply sufficient data?. Journal of Antimicrobial Chemotherapy, 64 5: 929-937. doi:10.1093/jac/dkp302

Thirlwell, J., Holley, A., Udy, A., Lipman, J. and Paratz, J. (2009) Editorial: The microcirculation, regional blood flow and tissue oxygenation: Will new technologies drive new resuscitation goals? (Anaesthesia and Intensive Care (2009) 37 (700-702)). Anaesthesia and Intensive Care, 37 6: .

Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009) Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 1: 210-215. doi:10.1128/AAC.00718-08

Holley, A, Udy, A and Lipman, J (2009) The microcirculation, regional blood flow and tissue oxygenation: will new technologies drive new resuscitation goals?. Anaesthesia and Intensive Care, 37 5: 700-702.

Roberts, Jason A., Udy, Andrew A., O'Donoghue, Stephen, Briscoe, Scott, Paterson, David L. and Lipman, Jeffrey (2009) Clearance of intravenous 5-fluorocytosine during continuous venovenous haemodiafiltration in a patient with hepatosplenic candidiasis. International Journal of Antimicrobial Agents, 34 4: 383-384. doi:10.1016/j.ijantimicag.2009.05.005

Roberts, Jason A., Coulthard, Mark G., Addison, Russell S., Foot, Carole and Lipman, Jeffrey (2009) Midazolam metabolism: Implications for individualised dosing?. Journal of Pharmacy Practice and Research, 39 3: 198-201.

Roberts, JA and Lipman, J (2009) Tissue Distribution of Beta-Lactam Antibiotics: Continuous versus Bolus Dosing. Journal of Pharmacy Practice and Research, 39 3: 219-222.

Roberts, Jason A. and Lipman, Jeffrey (2009) Dose matters: Dose of antibiotics in the critically ill patient depends on the dose of renal replacement therapy. Critical Care Medicine, 37 8: 2491-2492. doi:10.1097/CCM.0b013e3181aee840

Choi, Gordon, Gomersall, Charles D., Tian, Qi, Joynt, Gavin M., Freebairn, Ross and Lipman, Jeffrey (2009) Principles of antibacterial dosing in continuous renal replacement therapy. Critical Care Medicine, 37 7: 2268-2282. doi:10.1097/CCM.0b013e3181aab3d0

Holley, Anthony, Dulhunty, Joel, Blot, Stijn, Lipman, Jeffrey, Lobo, Suzana, Dancer, Craig, Rello, Jordi and Dimopoulos, George (2009) Temporal trends, risk factors and outcomes in albicans and non-albicans candidaemia: an international epidemiological study in four multidisciplinary intensive care units. International Journal of Antimicrobial Agents, 33 6: 554.e1-554.e7. doi:10.1016/j.ijantimicag.2008.10.035

Roberts, Jason A., Webb, Steven, Paterson, David, Ho, Kwok M. and Lipman, Jeffrey (2009) A systematic review on clinical benefits of continuous administration of [beta]-lactam antibiotics. Critical Care Medicine, 37 6: 2071-2078. doi:10.1097/CCM.0b013e3181a0054d

Boots, RJ, Dulhunty, JM, Paratz, JD and Lipman, J (2009) Respiratory Complications in Burns: An Evolving Spectrum of Injury. Clinical Pulmonary Medicine, 16 3: 132-138. doi:10.1097/CPM.0b013e3181a39032

Baek-Nam, Kim, Peleg, Anton Y., Lodise, Thomas P., Lipman, Jeffrey, Li, Jian, Nation, Roger and Paterson, David L. (2009) Management of meningitis due to antibiotic-resistant Acinetobacter species. Lancet Infectious Diseases, 9 4: 245-255. doi:10.1016/S1473-3099(09)70055-6

Udy, A., O'Donoghue, S., D'Intini, V., Healy, H. and Lipman, J. (2009) Point of care measurement of plasma creatinine in critically ill patients with acute kidney injury. Anaesthesia, 64 4: 403-407. doi:10.1111/j.1365-2044.2008.05818.x

Ho, KM and Lipman, J (2009) An update on C-reactive protein for intensivists.. Anaesthesia and Intensive Care, 37 2: 234-241.

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009) Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 3: 926-933. doi:10.1097/CCM.0b013e3181968e44

Udy, A., Senthuran, S. and Lipman, J. (2009) Airway obstruction due to a pre-vertebral haematoma following difficult central line insertion - implications for ultrasound guidance and review of the literature. Anaesthesia and Intensive Care, 37 2: 309-313.

Roberts, Jason A. and Lipman, Jeffrey (2009) Pharmacokinetic issues for antibiotics in the critically ill patient. Critical Care Medicine, 37 3: 840-851. doi:10.1097/CCM.0b013e3181961bff

Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009) Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 12: 5303-5305. doi:10.1128/AAC.01600-08

Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009) Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 6: xx-xx. doi:10.1186/cc8184

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009) Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 1: 142-150. doi:10.1093/jac/dkp139

Udy, A., Roberts, J. A., Boots, R. J. and Lipman, J. (2009) You only find what you look for: The importance of high creatinine clearance in the critically ill. Anaesthesia and Intensive Care, 37 1: 11-13.

Joel M. Dulhunty, Robert J. Boots, Michael J. Rudd, Michael J. Muller and Jeffrey Lipman (2008) Increased fluid resuscitation can lead to adverse outcomes in major-burn injured patients, but low mortality is achievable. Burns, 34 8: 1090-1097. doi:10.1016/j.burns.2008.01.011

John A Myburgh, Alisa Higgins, Alina Jovanovska, Lipman, Jeffrey, Naresh Ramakrishnan and John Santamaria (2008) A comparison of epinephrine and norepinephrine in critically ill patients. Intensive Care Medicine, 34 12: 2226-2234. doi:10.1007/s00134-008-1219-0

Dulhunty, Joel M., Lipman, Jeffrey and Finfer, Simon (2008) Does severe non-infectious SIRS differ from severe sepsis? Results from a multi-centre Australian and New Zealand intensive care unit study. Intensive Care Medicine, 34 9: 1654-1661. doi:10.1007/s00134-008-1160-2

Roberts, Jason A, Lipman, Jeffrey, Blot, Stijn and Rello, Jordi (2008) Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients?. Current Opinion in Critical Care, 14 4: 390-396. doi:10.1097/MCC.0b013e3283021b3a

Roberts, Jason A., Kruger, Peter, Paterson, David L. and Lipman, Jeffrey (2008) Antibiotic resistance - what's dosing got to do with it?. Critical Care Medicine, 36 8: 2433-2440. doi:10.1097/CCM.0b013e318180fe62

D. M. Roberts, J. A. Roberts, R. J. Boots, R. Mason and J. Lipman (2008) Lessons learnt in the pharmacokinetic analysis of the effect of haemoperfusion for acute overdose with sustained-release diltiazem. Anaesthesia, 63 7: 714-718. doi:10.1111/j.1365-2044.2008.05477.x

Jason A. Roberts, Jennifer D. Paratz and Jeffrey Lipman (2008) Continuous infusion of [beta]-lactams in the intensive care unit—Best way to hit the target?. Critical Care Medicine, 36 5: 1663-1664. doi:10.1097/CCM.0b013e3181704625

Roberts, Jason A., Paratz, Jennifer D., Paratz, Elizabeth D., Boots, Rob J. and Jeffrey Lipman (2008) Continuous infusion of time-dependent antibiotics: lung pharmacokinetics and pharmacodynamics. Clinical Pulmonary Medicine, 15 3: 167-172. doi:10.1097/CPM.0b013e3181729d3d

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008) A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 3: 240-244. doi:10.1016/j.ijantimicag.2007.09.013

Thomas, Peter J., Paratz, Jennifer D., Lipman, Jeffrey and Stanton, Warren R. (2007) Lateral positioning of ventilated intensive care patients: A study of oxygenation, respiratory mechanics, hemodynamics, and adverse events. Heart & Lung, 36 4: 277-286. doi:10.1016/j.hrtlng.2006.10.008

Dalley, Andrew J., Lipman, Jeffrey, Venkatesh, Bala, Rudds, Michael, Roberts, Michael S. and Cross, Sheree E. (2007) Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement. Journal of Antimicrobial Chemotherapy, 60 1: 166-169. doi:10.1093/jac/dkm128

Dhanani, J., Senthuran, S., Olivotto, R., Boots, R. J. and Lipman, J. (2007) Bedside prediction of central venous catheter insertion depth. British Journal of Anaesthesia, 98 5: 695-695. doi:10.1093/bja/aem080

Chatterjee, I., Iredell, J. R., Woods, M. and Lipman, J. (2007) The implications of enterococci for the intensive care unit. Critical Care and Resuscitation, 9 1: 69-75.

Marik, Paul E. and Lipman, Jeffrey (2007) The definition of septic shock: Implications for treatment. Critical Care and Resuscitation, 9 1: 101-103.

Paterson, D. L. and Lipman, J. (2007) Editorial: Infections in the intensive care unit - important questions remain. Critical Care and Resuscitation, 9 1: 3-4.

Roberts, J. A., Boots, R., Rickard, C. M., Thomas, P., Quinn, J., Roberts, D. M., Richards, B. and Lipman, J. (2007) Is continuous infusion ceftriaxone better than once-a-day dosing in intensive care? A randomized controlled pilot study. Journal of Antimicrobial Chemotherapy, 59 2: 285-291. doi:10.1093/jac/dkl478

Roberts, Jason A., Webb, Steven A. R. and Lipman, Jeffrey (2007) Cefepime versus ceftazidime: Considerations for empirical use in critically ill patients. International Journal of Antimicrobial Agents, 29 2: 117-128. doi:10.1016/j.ijantimicag.2006.08.031

Roos, J. F., Lipman, J. and Kirkpatrick, C. M. J. (2007) Population pharmacokinetics and pharmacodynamics of cefpirome in critically ill patients against Gram-negative bacteria. Intensive Care Medicine, 33 5: 781-788. doi:10.1007/s00134-007-0573-7

Paterson, David and Lipman, Jeffery (2007) Returning to the pre-antibiotic era in the critically ill: The XDR problem. Critical Care Medicine, 35 7: 1789-1791. doi:10.1097/01.CCM.0000269352.39174.A4

Freshwater-Turner, D., Udy, A., Lipman, J., Deans, R., Stuart, J., Boots, R., Hegde, R. and McWhinney, B.C. (2007) Autonomic dysfunction in tetanus - what lessons can be learnt with specific reference to alpha-2 agonists?. Anaesthesia, 62 10: 1066-1070. doi:10.1111/j.1365-2044.2007.05217.x

Shorr, A. F. and Lipman, J. (2007) Resistance in the intensive care unit: Whose problem is it and how can intensivists help?. Critical Care Medicine, 35 1: 299-301. doi:10.1097/01.CCM.0000251292.74846.00

Dhanani, J., Senthuran, S., Olivotto, R., Boots, R. J. and Lipman, J. (2007) The Entrapped Central Venous Catheter. British Journal of Anaesthesia, 98 1: 89-92. doi:10.1093/bja/ael286

Roberts, Jason A. and Lipman, Jeffrey (2007) Optimizing use of ß-lactum antibiotics in the critically ill. Seminars in Respiratory and Critical Care Medicine, 28 6: 579-585. doi:10.1055/s-2007-996404

Roberts, Jason A., Paratz, Jennifer, Paratz, Elizabeth, Krueger, Wolfgang A. and Lipman, Jeffrey (2007) Continuous infusion of beta-lactam antibiotics in severe infections: a review of its role. International Journal of Antimicrobial Agents, 30 1: 11-18. doi:10.1016/j.ijantimicag.2007.02.002

Holley, A., Cartner, M. and Lipman, J. (2007) Acute respiratory distress in a bleomycin primed patient: a new use for nitric oxide. Anaesthesia and Intensive Care, 35 1: 86-90.

Eisen, Damon P., Dean, Melinda M., Thomas, Peter, Marshall, Penny, Gerns, Natalie, Heatley, Sue, Quinn, Josephine, Minchinton, Robyn M. and Lipman, Jeff (2006) Low mannose-binding lectin function is associated with sepsis in adult patients. FEMS Immunology and Medical Microbiology, 48 2: 274-282. doi:10.1111/j.1574-695X.2006.00144.x

Thomas, Peter J., Paratz, Jennifer D., Stanton, Warren R., Deans, Renae and Lipman, Jeffrey (2006) Positioning practices for ventilated intensive care patients: Current practice, indications and contraindications. Australian Critical Care, 19 4: 122-132. doi:10.1016/S1036-7314(06)80025-1

Shorr, Andrew F., Jackson, William L. and Lipman, Jeffrey (2006) Making the wrong choice: Consequences for patients with infections due to methicillin-resistant Staphylococcus aureus. Critical Care Medicine, 34 8: 2239-2241. doi:10.1097/01.CCM.0000229635.52805.50

Tian, Qi, Gomersall, Charles D., Wong, April, Leung, Patricia, Choi, Gordon, Joynt, Gavin M., Tan, Perpetua and Lipman, Jeff (2006) Effect of drug concentration on adsorption of levofloxacin by polyacrylonitrile haemofilters. International Journal of Antimicrobial Agents, 28 2: 147-150. doi:10.1016/j.ijantimicag.2006.03.025

Paratz, Jennifer and Lipman, Jeffrey (2006) Manual hyperinflation causes norepinephrine release. Heart & Lung, 35 4: 262-268. doi:10.1016/j.hrtlng.2005.12.002

Finfer, S., Felton, T., Blundell, A. and Lipman, J. (2006) Estimate of the number of patients eligible for treatment with drotrecogin alfa (activated) based on differing international indications: Post-hoc analysis of an inception cohort study in Australia and New Zealand. Anaesthesia And Intensive Care, 34 2: 184-190.

Roos, Juliana F., Bulitta, Jurgen, Lipman, Jeffrey and Kirkpatrick, Carl M. J. (2006) Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units. Journal of Antimicrobial Chemotherapy, 58 5: 987-993. doi:10.1093/jac/dkl349

Roberts, J. A. and Lipman, J. (2006) Antibacterial dosing in intensive care: Pharmacokinetics, degree of disease and pharmacodynamics of sepsis. Clinical Pharmacokinetics, 45 8: 755-773. doi:10.2165/00003088-200645080-00001

Li, J., Rayner, C. R., Nation, R. L., Deans, R., Boots, R., Widdecombe, N., Douglas, A. and Lipman, J. (2005) Pharmacokinetics of colistin methanesulfonate and colistin in a critically ill patient receiving continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 49 11: 4814-4815. doi:10.1128/AAC.49.11.4814-4815.2005

Ho, K. M., Lipman, J., Dobb, G. J. and Webb, S. A. R. (2005) The use of prophylactic fluconazole in immunocompetent high-risk surgical patients: A meta-analysis. Critical Care, 9 6: R710-R717. doi:10.1186/cc3883

Thomas, Peter J., Williams, Marie and Lipman, Jeffrey (2005) Influence of academic qualifications, place of employment and prior research experience on physiotherapy research practice. The Internet Journal of Allied Health Sciences and Practices, 3 3: .

Lipman, Jeffrey (2005) Is the end-game penetration (of the airway)?. Critical Care Medicine, 33 7: 1654-1655. doi:10.1097/01.CCM.0000170183.83774.F6

Rechner, I. J. and Lipman, J. (2005) The costs of caring for patients in a tertiary referral Australian intensive care unit. Anaesthesia and Intensive Care, 33 4: 477-482.

Iredell, J. and Lipman, J. (2005) Antibiotic resistance in the intensive care unit: A primer in bacteriology. Anaesthesia and Intensive Care, 33 2: 188-195.

Boots, R. J., Lipman, J., Bellomo, R., Stephens, D. and Heller, R. E. (2005) Disease risk and mortality prediction in intensive care patients with pneumonia. Australian and New Zealand practice in intensive care (ANZPIC II). Anaesthesia And Intensive Care, 33 1: 101-111.

Boots, R. J., Lipman, J., Bellomo, R., Stephens, D. and Heller, R. E. (2005) Australian and New Zealand practice in intensive care (ANZPIC II: The spectrum of practice in the diagnosis and management of pneumonia in patients requiring mechanical ventilation. Anaesthesia and Intensive Care, 33 1: 87-100.

Gous, Andries, Lipman, Jeffrey, Scribante, Juan, Tshukutsoane, Shephelia, Hon, Hubert, Pinder, Mary, Mathivha, Rudo, Verhoef, Lia and Stass, Heino (2005) Fluid shifts have no influence on ciprofloxacin pharmacokinetics in intensive care patients with intra-abdominal sepsis. International Journal of Antimicrobial Agents, 26 1: 50-55. doi:10.1016/j.ijantimicag.2005.04.005

Boots, R. J., Lipman, J., Bellomo, R., Stephens, D. and Heller, R. F. (2005) Australian and New Zealand practice in intensive care (ANZPIC II): Predictors of physician confidence to diagnose pneumonia and determine illness severity in ventilated patients. Anaesthesia and Intensive Care, 33 1: 112-119.

Choi, Gordon, Gomersall, Charles D.,

Professor Jeffrey Lipman

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